Gene Information

Name : lysS (Lcho_0288)
Accession : YP_001789328.1
Strain : Leptothrix cholodnii SP-6
Genome accession: NC_010524
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 304617 - 306161 bp
Length : 1545 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGAGCCACCCGACTCCCCATCACGCCGCAGCCCCCGTCGCGGCCGACGAAAACCAGCTCATGGCCGAACGCCGCGAAAA
ACTCGCCGTGATGCGCCAGCAGCACCGCGAGGCCGGCACCGCGGTCTTCCCGAACGACTTCAAGCCCACCGACCACGCCA
CCGACCTGCACCGCCTGCATGAAGGCAAGGACAACGAGGCGCTCGAAGCCGCGCCGATCACCGCCTGCGTGGCCGGCCGC
ATGATGCTCAAGCGCGTGATGGGCAAGGCCTGTTTCGCCACGCTGCAGGACGGCTCGGCCGACGGCAACCCGCGCATCCA
GCTCTACATCACGCAGGACAACGTCGGTGCCGAACTGCTGGCCGCCTTCAAGCACTGGGACCTGGGCGACATCCTGGGTG
CCACCGGCACGCTGTTTCGCACCAAGAGCGGCGAGCTGTCGATCAAGGTGACCGGCCTGCGCCTGCTCACCAAGAGCCTG
CGGCCGATGCCCGACAAGCACCACGGCATGACCGACCAGGAGCAGAAGTACCGCCAGCGCTACGTCGACCTGATGACCGA
CGACAGCGCGCGCGAGCGTTTCCGCGCCCGCAGCAAGGCGGTGGCGAGCATCCGCGGCTTCATGCTGGAGCACCAGTTCC
TGGAGGTCGAGACGCCGATGCTGCACCCGATCCCGGGTGGCGCGAACGCAAAGCCGTTTGTCACGCACCACAACGCGCTC
GACCAGGAGATGTTCCTGCGCATCGCGCCCGAGCTGTACCTCAAGCGCTTGGTGGTGGGCGGTTTCGAGCGCGTGTTCGA
GATCAACCGCAACTTCCGCAACGAAGGCATCTCGGTTCGGCACAACCCCGAATTCACGATGATGGAGTTCTACGCGGCGT
ACTGGAATCACCACGACCTGATGGACTTCACCGAGCAGCTGCTGCGCCACGCCGCCACGCAGGCCACCGGCTCGGCGCGG
GTCAGCTACGCCGGCAAGCCGGTGCATCTGGACGAGCCGTTCGCGCGGCTGTCGGTGCGTGATTCGCTGGTGGTGCATGC
CGGTCTCACCGAAGCCGAAGCCGACGATGCCGCGGTGATCCACGCCAAGCTGACCTCGCTCGGTGAAGAGCCGCCCAAGC
ACTGGAAGCTGGCGGCGCTGCAGTTCGGCCTGTTCGAGGCGGTGGTCGAAGAGAAGCTCTGGCAGCCGACATTCATCATC
GACTACCCGGTCGAGGTGTCGCCGCTGGCGCGCGCATCCGACGCCAACCCGTCGATCACCGAGCGCTTCGAGCTGTTCAT
CACCGGCCGCGAATTCGGCAACGGCTTCAGCGAGCTGAACGACGCCGAGGACCAGGCCGCGCGCTTCCAGAGCCAGGTCG
CCAACAAGGACGCCGGCGATGAAGAGGCGATGTTCTACGACGCCGACTTCATCCGCGCGCTCGAATACGGCATGCCCCCG
ACGGGCGGCTGCGGCATCGGCATCGACCGGCTGATGATGCTGCTGACCGACAGCGTGAGCATCCGCGACGTGGTGCTGTT
CCCGGCGCTGCGGCGCGAGGGCTGA

Protein sequence :
MSHPTPHHAAAPVAADENQLMAERREKLAVMRQQHREAGTAVFPNDFKPTDHATDLHRLHEGKDNEALEAAPITACVAGR
MMLKRVMGKACFATLQDGSADGNPRIQLYITQDNVGAELLAAFKHWDLGDILGATGTLFRTKSGELSIKVTGLRLLTKSL
RPMPDKHHGMTDQEQKYRQRYVDLMTDDSARERFRARSKAVASIRGFMLEHQFLEVETPMLHPIPGGANAKPFVTHHNAL
DQEMFLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMEFYAAYWNHHDLMDFTEQLLRHAATQATGSAR
VSYAGKPVHLDEPFARLSVRDSLVVHAGLTEAEADDAAVIHAKLTSLGEEPPKHWKLAALQFGLFEAVVEEKLWQPTFII
DYPVEVSPLARASDANPSITERFELFITGREFGNGFSELNDAEDQAARFQSQVANKDAGDEEAMFYDADFIRALEYGMPP
TGGCGIGIDRLMMLLTDSVSIRDVVLFPALRREG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-128 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001789328.1 lysyl-tRNA synthetase VFG1668 Protein 1e-128 53