Gene Information

Name : Lcho_2430 (Lcho_2430)
Accession : YP_001791460.1
Strain : Leptothrix cholodnii SP-6
Genome accession: NC_010524
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 2638559 - 2640445 bp
Length : 1887 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAATGCCCCCGACAAGCTGCAAGACCTGCTCTCGCTGACCCGCGAACCCTTCCCCGCCTCGCGCAAGGTCTACGCCGA
GGGCTCCGAGGGCGTGCGCGTGCCGATGCGCGAGATCGCGCTGACCAACGGCGAGCGCGTCACGGTCTACGACACCTCCG
GCCCCTACACCGATCCGCTCGCGACGATCGACGCCAAGCTCGGCCTGCCGAGCGTGCGCACCGGCTGGATCGAGGCCCGC
GGCGACACCGAGACCTACGCCGGCCGCAACCGCGTGGCGCTGGACGACGGCGGCAAGCACGAGGAAACGGCGCGCATCGA
AGCCCTGCGCGCCCAGGCCGCCGCGCTGCAGCGCACGCCGCGCCGCGCCAAGGCTGGCGGCAACGTGACGCAGATGCACT
ACGCCCGCCGCGGCATCGTCACGCCCGAGATGGAGTACGTGGCGATCCGCGAAAACGGCAAGCGCGAATGGATGCGCGAG
TACCTGGGCGACGCCGAGCGCGAGGCCCGCCTGGCCGGCAATGCCAAGGGCGCGCGCATCCCCGAGATCTACACGCCCGA
GTTCGTGCGCGACGAGGTGGCGCGCGGGCGCGCGATCATCCCGGCCAACATCAACCACCCCGAGGTGGAACCGATGGCGA
TCGGGCGCAACTTCGGCGTCAAGATCAACGCCAACATCGGCAACTCGGCGGTGACGTCGAGCATCGAGGAAGAAGTCGAG
AAACTCGTGTGGGCGATCCGCTGGGGCGCCGACAACGTGATGGACCTGTCGACCGGCCGCAACATCCACACCACGCGCGA
CTGGATCGTGCGCAACAGCCCCGTGCCCATCGGCACCGTGCCGATCTACCAGGCGCTCGAGAAGGTCGGCGGCATCGCCG
AAGACCTGACCTGGGCGATCTACCGCGACACGCTGATCGAGCAGGCCGAACAGGGCGTCGACTACTTCACCATCCACGCG
GGGGTGCGCCTGCCGTTCATCCACCTGACGGCGAATCGGCGCACCGGCATCGTCTCGCGCGGCGGCTCGATCCTGGCCAA
GTGGTGCATCACGCATCACAAGGAAAACTTCCTGTACACGCACTTCGAAGAGATCTGCGAAATCATGAAGGCCTACGACG
TCAGCTTCTCGCTCGGCGACGGCCTGCGTCCGGGCTCGGCGTCCGACGCCAACGACGCGGCGCAGTTCGCCGAGCTGAAG
ACGCTGGGCGAGCTGACGCAGGTGGCCTGGAAACACGACGTACAGACCATGATCGAAGGCCCCGGCCACGTGCCGATGCA
CCTGATCCAGGCCAACATGGACGAGCAGATCAAGCACTGCCACGAGGCGCCGTTCTACACGCTCGGGCCCTTGACGATCG
ACATCGCACCCGGCTACGACCACATTGCGTCAGCGATCGGCGCAGCCATGATCGGCTGGATGGGCACGGCGATGCTGTGC
TACGTGACGCCCAAGGAGCACCTCGGCCTGCCCGACCGCGACGACGTCAAGCAGGGCATCATTGCCTACAAGATCGCCGC
GCACGCGGCCGACATCGCCAAGGGCCACCCGGGTGCACGGGCCCGTGACGACGCGATGAGCAAGGCGCGCTTCGAGTTCC
GCTGGCACGACCAGTTCAACCTCGGCCTCGACCCCGACACGGCGCGCGACTATCACGACGAGACGCTGCCGAAGGACTCC
AGCAAGGAAGCGCATTTCTGCAGCATGTGCGGGCCGAAGTTCTGCTCGATGAAGATCACGCAGGACGTGCGCGACTACGC
CGCGGCCAAGGGCTTGAGCGAGGAGCAGGCGCTGGCCGACGTCGAACAAGGCATGGCGGCCAAGTCGGCCGAGTTCAAGG
CGCAGGGCGGCGAGCTCTACATCCCGATCACGCCGGTGCAGGCCTGA

Protein sequence :
MNAPDKLQDLLSLTREPFPASRKVYAEGSEGVRVPMREIALTNGERVTVYDTSGPYTDPLATIDAKLGLPSVRTGWIEAR
GDTETYAGRNRVALDDGGKHEETARIEALRAQAAALQRTPRRAKAGGNVTQMHYARRGIVTPEMEYVAIRENGKREWMRE
YLGDAEREARLAGNAKGARIPEIYTPEFVRDEVARGRAIIPANINHPEVEPMAIGRNFGVKINANIGNSAVTSSIEEEVE
KLVWAIRWGADNVMDLSTGRNIHTTRDWIVRNSPVPIGTVPIYQALEKVGGIAEDLTWAIYRDTLIEQAEQGVDYFTIHA
GVRLPFIHLTANRRTGIVSRGGSILAKWCITHHKENFLYTHFEEICEIMKAYDVSFSLGDGLRPGSASDANDAAQFAELK
TLGELTQVAWKHDVQTMIEGPGHVPMHLIQANMDEQIKHCHEAPFYTLGPLTIDIAPGYDHIASAIGAAMIGWMGTAMLC
YVTPKEHLGLPDRDDVKQGIIAYKIAAHAADIAKGHPGARARDDAMSKARFEFRWHDQFNLGLDPDTARDYHDETLPKDS
SKEAHFCSMCGPKFCSMKITQDVRDYAAAKGLSEEQALADVEQGMAAKSAEFKAQGGELYIPITPVQA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 68
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 68
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 4e-179 65