Gene Information

Name : smpB (Lcho_2057)
Accession : YP_001791089.1
Strain : Leptothrix cholodnii SP-6
Genome accession: NC_010524
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 2237220 - 2237684 bp
Length : 465 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGAGCATCGCCGAAAACAAGAAAGCTTTTTTCAACTACCACATCGAAGAGCGCTTCGAAGCCGGCATCGTGCTGGCAGG
CTGGGAGATCAAGTCGATCCGCTCGGGTCAGATCCAGTTGACCGACGGCTACGTGGTGATCAAGGACGGCGAGCTGTTCC
TGATCGGCCTGCGCATCAACGCGCTGCGCAGCGCCTCCACGCACGTCAACCCCGAGCCCGACCGCACCAAGAAGCTCCTG
ATGCACAAGGCCGAGATCCGCCGCCTGATCGGCAAGGTCGAGCAGAAGGGCCACACGCTGGTGCCGCTGAACCTGCACTA
CAAGGGCGGCCGCGTGAAGGTGGACGTGGCGCTGGCCAAGGGCAAGGCCGAACACGACAAGCGCCACACCATCAAGGACC
GCGACTGGCAGCGCGAACAGGGCCGGCTGATGCGCCACAAGGTGTCGGCGCCGCACAAGGACTGA

Protein sequence :
MSIAENKKAFFNYHIEERFEAGIVLAGWEIKSIRSGQIQLTDGYVVIKDGELFLIGLRINALRSASTHVNPEPDRTKKLL
MHKAEIRRLIGKVEQKGHTLVPLNLHYKGGRVKVDVALAKGKAEHDKRHTIKDRDWQREQGRLMRHKVSAPHKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 4e-31 46
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 1e-23 44
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 2e-23 42