Gene Information

Name : Lcho_2019 (Lcho_2019)
Accession : YP_001791051.1
Strain : Leptothrix cholodnii SP-6
Genome accession: NC_010524
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2190970 - 2193567 bp
Length : 2598 bp
Strand : -
Note : KEGG: mpt:Mpe_A1549 putative ATP-dependent protease (heat shock protein); TIGRFAM: ATP-dependent chaperone ClpB; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain pro

DNA sequence :
ATGCGACTCGACAAGCTCACGACTGCTTTCCAACAAGCCCTGGCCGACGCGCAGAGCTTGGCCATCAACCGCGACAACCC
CTACATCGAACCGGCCCACCTGTTGGCGGCGATGCTGGCGATGCAGGACGGCCCGAAGGCCTTGCTCGACCGCGCCGGCG
CCAACACCGCGGCGCTGAAAACCGCGATGGACACGCTGATCAGGGGCCTGCCGCAGGTCGAGGGCAGCGGTCAGTCGGTG
CAGCCGGGCCGTGATCTGCTCGCGCTGCTGCAGGCGGCTGAAAAGGATGCCGGCAAGCGCGGCGACCAGTTCGTCAGCAG
CGAGCTGTTCCTGCTGGCGGTGGCCGACAGCAAGAGCGACATCGGCGGCGTGGTGCGTGGTCACGGCCTGACGCGCAAGG
CGCTCGAGGCCGCGATCGACGCGGTGCGCGGTGGCGCCACGGTCGACAACGCCGAGGCCGAAGGCCAGCGCGAGGCGCTC
AAGAAATACACGCTCGACCTGACCGAGCGCGCCCGCATGGGCAAGCTCGACCCGGTGATCGGCCGCGACGACGAGATCCG
CCGCGCCATCCAGGTGCTGCAGCGCCGCAGCAAGAACAACCCGGTGCTGATCGGCGAGCCGGGTGTCGGCAAGACCGCGA
TCGTCGAGGGCCTGGCGCAGCGCATCGTCAACGGCGAGGTGCCCGAGAGCCTGAAGAACAAGCGCGTGCTGGTGCTCGAC
ATGGCCGGGCTGCTGGCCGGCGCCAAGTACCGCGGCGAGTTCGAGGAGCGCCTGAAGGCGGTGCTCAAGGAAGTGGCCGC
CGACGAGGGCCGCATCATCCTGTTCATCGACGAGCTGCACACGATGGTCGGCGCCGGCAAGGCCGAGGGCGCGATCGACG
CCGGCAACATGCTCAAGCCCGCGCTGGCGCGTGGCGAGCTGCACTGCATCGGCGCGACCACGCTCAACGAATACCGCAAG
TACGTCGAGAAGGACGCCGCGCTGGAGCGGCGTTTCCAGAAGGTGCTGGTCGACGAACCGAGCGTGGAGGCCACGGTCGC
CATCCTGCGCGGCCTGCAGGAAAAGTACGAGGTGCACCACGGCGTGCAGATCACCGACCCGGCCATCATCGCCGCGGCCG
AGCTGAGCCACCGCTACGTCACCGACCGCTTCCTGCCCGACAAGGCGATCGACCTGATCGACGAGGCGGCGGCCAAGATC
AAGATCGAGATGGACTCCAAGCCGGAGTCGATGGACAAGCTCGATCGCCGGCTGATCCAGCTCAAGATCGAGCGCGAGGC
GGTGCGCAAGGAGAAGGACGAAGGTTCGGTGCGCCGCTTCGGCCTGATCGAGGAAGAGATCGCCAAGCTCGAACGCGAAG
CGGCCGATCTGGAGGAGATCTGGAAGGCTGAAAAGGCCGCCGCGCAGGGTTCCAAGCAGTTCATGGAAGAGATCGAGAGC
GCGCGCCTGCAGATCGAGGAGTTCAAGCGCAAGGGCGATTTCAACCGCGTGGCCGAGTTGCAGTACGGCAAGCTGCCCGA
GCTGGAAAAGAAGCTGCACGACGCCCAGGCCAAGGAGGCCGGCAAGGCCAAGGGCGGTCAGGGCCCGCAACTGCTGCGCA
CGGTGGTGGGCGCCGAGGAGATCGCCGAGGTGGTGTCGCGTGCCACCGGCATCCCGGTGGCCAAGCTGATGCAGGGCGAG
CGCGACAAGCTGCTGCAGATGGAAGGCAAGCTGCACGACCGCGTGGTCGGCCAGAGCGAGGCGATCATCGCGGTGAGCAA
CGCGATCCGGCGTTCACGCGCCGGCTTGAGCGACCCGAACCGGCCGCTCGGCAGCTTCCTGTTCCTGGGGCCCACCGGCG
TCGGCAAGACCGAGCTGTGCAAGGCGCTGGCGGGTTTCCTGTTCGACAGCGACGACCACATGATCCGCATCGACATGAGC
GAGTTCATGGAGAAGCACTCGGTGAGCCGGCTGATCGGCGCGCCCCCGGGTTACGTCGGTTATGACGAAGGCGGCTACCT
GACCGAGGCGGTGCGCCGCAAGCCTTACAGCGTGCTGCTGCTCGACGAGGTCGAGAAGGCGCATCCGGACGTCTTCAACG
TGCTGCTGCAGGTGCTCGACGACGGCCGCCTGACCGACGGGCAGGGCCGCACGGTCGACTTCAAGAACACCGTGATCGTG
ATGACCAGCAACCTGGGCTCGCACCAGATCATGCAGATGGCCGGGCAGGACACCGAGCTGATCCGCGAGGCGGTGTGGGC
CGAGGTCAAGCAGCATTTCCGCCCGGAGTTCCTGAACCGCATCGACGAGGCGGTGGTGTTCCATGCGCTCGACCAGAAGC
ACATCGAGGCGATCGCGCAGATCCAGCTGAAGGCGCTGGCGGCGCGGCTGGGCAAGATGGAGATGACGCTGGAGGTCTCG
CCCGAGGCGCTGGCCGAGCTGGCGAAGGTCGGCTTCGATCCGGTGTTCGGCGCGCGGCCGCTCAAGCGGGCGATCCAGCA
GCGCATCGAGAACCCGGTCGCCAAGCTGATCCTGGAGGGCCGCTTCGGCCCGAAGGACGTGGTGCCGGTCAACGTCGGCG
CCACCGGCGACTTCGAGTTCGGCCGCACGGTGCACTGA

Protein sequence :
MRLDKLTTAFQQALADAQSLAINRDNPYIEPAHLLAAMLAMQDGPKALLDRAGANTAALKTAMDTLIRGLPQVEGSGQSV
QPGRDLLALLQAAEKDAGKRGDQFVSSELFLLAVADSKSDIGGVVRGHGLTRKALEAAIDAVRGGATVDNAEAEGQREAL
KKYTLDLTERARMGKLDPVIGRDDEIRRAIQVLQRRSKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPESLKNKRVLVLD
MAGLLAGAKYRGEFEERLKAVLKEVAADEGRIILFIDELHTMVGAGKAEGAIDAGNMLKPALARGELHCIGATTLNEYRK
YVEKDAALERRFQKVLVDEPSVEATVAILRGLQEKYEVHHGVQITDPAIIAAAELSHRYVTDRFLPDKAIDLIDEAAAKI
KIEMDSKPESMDKLDRRLIQLKIEREAVRKEKDEGSVRRFGLIEEEIAKLEREAADLEEIWKAEKAAAQGSKQFMEEIES
ARLQIEEFKRKGDFNRVAELQYGKLPELEKKLHDAQAKEAGKAKGGQGPQLLRTVVGAEEIAEVVSRATGIPVAKLMQGE
RDKLLQMEGKLHDRVVGQSEAIIAVSNAIRRSRAGLSDPNRPLGSFLFLGPTGVGKTELCKALAGFLFDSDDHMIRIDMS
EFMEKHSVSRLIGAPPGYVGYDEGGYLTEAVRRKPYSVLLLDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFKNTVIV
MTSNLGSHQIMQMAGQDTELIREAVWAEVKQHFRPEFLNRIDEAVVFHALDQKHIEAIAQIQLKALAARLGKMEMTLEVS
PEALAELAKVGFDPVFGARPLKRAIQQRIENPVAKLILEGRFGPKDVVPVNVGATGDFEFGRTVH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 1e-135 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lcho_2019 YP_001791051.1 ATP-dependent chaperone ClpB VFG2076 Protein 7e-113 44
Lcho_2019 YP_001791051.1 ATP-dependent chaperone ClpB VFG2084 Protein 3e-101 41