Gene Information

Name : Lcho_1259 (Lcho_1259)
Accession : YP_001790293.1
Strain : Leptothrix cholodnii SP-6
Genome accession: NC_010524
Putative virulence/resistance : Resistance
Product : dihydrofolate reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0262
EC number : 1.5.1.3
Position : 1345906 - 1346406 bp
Length : 501 bp
Strand : -
Note : PFAM: dihydrofolate reductase region; KEGG: mpt:Mpe_A2052 dihydrofolate reductase

DNA sequence :
ATGACGCGCATCGTGCTGATCGCCGCCGTGGCGCGCAACGGCGTGATCGGCCGTGACAACGACCTGCCCTGGCGCCTGCC
GGAAGACCTGCAGTTCTTCCGCCGCACGACGATGGGACATCCGGTGCTGATGGGCCGGCGCAACTGGGACTCGCTGCCGG
CGAAGTTCCGCCCGCTGCCCGGGCGCCACAACCTCGTGCTGACGCGCAATCCGGACTGGCGCGCCGAGGGCGCCACCGTC
GTGCACAGCCTGGCGCAGGCGCTCGATCAGCTGGGCGATGTGCCCACGCTGTTCGTCATCGGCGGCGGCGAGCTGTACCG
GCTGGCGCTGCCGCTGGCCGACGAGATCATCCTCACCGAGATCGACCGGGCGGTCGACGGCGACGTGTTTTTCCCGCACT
GGGACCGCAGTGCCTTCGAGGTGCTGTCCCGCGAAACGCACGCAGCCGATGGCAGTGATGCCATCGGCTACGAACGCGTG
CACCATCGCAAAAAGCCCTGA

Protein sequence :
MTRIVLIAAVARNGVIGRDNDLPWRLPEDLQFFRRTTMGHPVLMGRRNWDSLPAKFRPLPGRHNLVLTRNPDWRAEGATV
VHSLAQALDQLGDVPTLFVIGGGELYRLALPLADEIILTEIDRAVDGDVFFPHWDRSAFEVLSRETHAADGSDAIGYERV
HHRKKP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dfrA12 ACF06156.1 dihydrofolate reductase Not tested Tn5036-like Protein 2e-28 42