Gene Information

Name : CLK_2843 (CLK_2843)
Accession : YP_001788740.1
Strain : Clostridium botulinum Loch Maree
Genome accession: NC_010520
Putative virulence/resistance : Virulence
Product : alkaline phosphatase synthesis transcriptional regulatory protein PhoP
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 3741928 - 3742608 bp
Length : 681 bp
Strand : -
Note : identified by match to protein family HMM PF00072; match to protein family HMM PF00486

DNA sequence : 
TTGAAGAATTTTAAGATCCTTTTAGTAGAAGATGAAGAGCAAATGTCAATGTTTATTGAAATGGAGCTTACTCATGAAGG
TTATAAAGTTGATGTAGCTTATGACGGAAGAGAAGCTTTAGAGAAAGTGGAAAATACAGAATATCAGTTAATACTTCTTG
ATATTATGATACCGGGTTTAAATGGGATTGAGGTTTGTAGAAGGATTAGGCAATTTTCTTGTGTACCTATAATAATGCTA
ACTGCAAAAAGTGATGTATCGGACAAAGTTCTAGGACTTGACGTTGGGGCTAATGATTATTTAACTAAACCTTTTGCAAT
AGAGGAATTATTGGCAAGAATACGAGTATATGAACGAGAAAAGTTAGTAAAGAGTAAATTTGATGAAGTTAAAGTAAAAG
ATATTGTGATGGATAATAAGACACATCAAGTTTGGAGGTCTGGAAGAGAAATTGAACTTACAAAAAAAGAATATGATCTT
CTTCAAAAGCTGTTAATTAATAAAAACATTGTGCTTACAAGAGAACGATTAATTGAAGAGGTATGGGGCTATGATTATGT
AGGAGATACTAATGTAGTAGATGTATTTATAAGATATTTACGAAGTAAAATTGATAATGGTTCTAAAGAGAAGCTTATAA
CTACAATAAGAGGTGTAGGCTATGTTATTAAAGATAATTAA

Protein sequence : 
MKNFKILLVEDEEQMSMFIEMELTHEGYKVDVAYDGREALEKVENTEYQLILLDIMIPGLNGIEVCRRIRQFSCVPIIML
TAKSDVSDKVLGLDVGANDYLTKPFAIEELLARIRVYEREKLVKSKFDEVKVKDIVMDNKTHQVWRSGREIELTKKEYDL
LQKLLINKNIVLTRERLIEEVWGYDYVGDTNVVDVFIRYLRSKIDNGSKEKLITTIRGVGYVIKDN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 1e-38 43
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 5e-38 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_002952.2859858.p0 Protein 3e-52 54
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_007622.3794948.p0 Protein 3e-52 54
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_003923.1003417.p0 Protein 3e-52 54
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_013450.8614146.p0 Protein 3e-52 54
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_002951.3238224.p0 Protein 3e-52 54
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_007793.3914065.p0 Protein 3e-52 54
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_002758.1121390.p0 Protein 3e-52 54
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_010079.5776364.p0 Protein 3e-52 54
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP AE015929.1.gene1106. Protein 2e-46 52
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP HE999704.1.gene1528. Protein 2e-45 52
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP BAC0125 Protein 9e-42 43
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_012469.1.7685629. Protein 2e-39 43
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP BAC0308 Protein 3e-36 43
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_002952.2859905.p0 Protein 4e-39 43
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_007622.3794472.p0 Protein 4e-39 43
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_002745.1124361.p0 Protein 5e-39 43
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_009782.5559369.p0 Protein 5e-39 43
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_002951.3237708.p0 Protein 5e-39 43
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_002758.1121668.p0 Protein 5e-39 43
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_009641.5332272.p0 Protein 5e-39 43
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_013450.8614421.p0 Protein 5e-39 43
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_007793.3914279.p0 Protein 5e-39 43
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_003923.1003749.p0 Protein 5e-39 43
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NC_012469.1.7686381. Protein 8e-39 42
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP AE000516.2.gene3505. Protein 6e-35 42
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP BAC0111 Protein 8e-35 41
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP BAC0197 Protein 2e-35 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP VFG0596 Protein 4e-39 43
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP VFG1390 Protein 2e-45 42
CLK_2843 YP_001788740.1 alkaline phosphatase synthesis transcriptional regulatory protein PhoP VFG1389 Protein 5e-39 42