Gene Information

Name : thiC (CLK_2303)
Accession : YP_001788232.1
Strain : Clostridium botulinum Loch Maree
Genome accession: NC_010520
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 3172076 - 3173389 bp
Length : 1314 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAATTATACAACTCAAATGGATGCGGCTAAAAAAGGAATAGTTACAAAAGAGATGGAAATAGTAGCTAAAAAGGAAAA
TATGAATGTGAAAGACCTTATGGAATTGGTATCTAAAGGTAAGGTTGCTATACCTGCTAATAAAAATCATAAATCTTTAG
ATCCAGAAGGAATAGGACAAGGTTTAAGAACTAAAATAAATGTTAATTTAGGAATATCTAAAGATTGCTATAATATAGAT
ATGGAATTAGAAAAAGTACAAAAAGCAATAGATATGAAGGCAGAAGCTATAATGGATTTGAGCTGCTTTGGGAAAACAGA
AGAATTTAGAAAAAGATTGATAGACATGTCACCAGCCATAATAGGTACTGTTCCTATATATGATGCAGTAGGTTTCTATG
ATAAAGAATTAAAAGATATTACATCAGAAGAATTTTTAAAGGTGGCAGAGAAACATGTAGAGAATGGAGCAGACTTTTTA
ACAATACATGTAGGTATGAATAGAAAAACTGCATCTACATTTAAGAAAAATCCAAGAAGAATGAACATAGTTTCAAGAGG
GGGATCTCTTTTATATGCATGGATGGAACTAAATAATAAAGAAAATCCATTCTATGAAAGATTTGATGAACTTTTAGATA
TATGTGAAAAGTATGATGTTACATTAAGCTTAGGGGATGCTTGCCGTCCAGGATGTATAGAGGATTCTACAGATGCAAGC
CAGATAGAAGAGCTTATAGCTTTAGGGGAACTTACCAAAAGAGCCTGGGATAGGAATGTACAAGTTATAATAGAGGGACC
AGGACATATGACTTTAGATGAAATAGAAACAAATATGAAAATAGAGAAAAAATTATGTCATGGAGCTCCGTTCTATGTTT
TAGGACCAATAGTTACAGATATAGCTCCAGGTTATGATCACATAACTTCAGCTATAGGTGGTGCCATTGCAGCAACTCAT
GGTGCAGATTTCTTATGCTATGTAACTCCAGCAGAACATTTAAGATTACCAAATTTGGATGATATGAAGGAAGGTATAAT
AGCGACAAAGATAGCAGCTCATGCAGCAGATTTAGCTAAAGGGGTAAAAGGAGCAAGAGATTGGGATAATGCTATGGCTA
AAGCTAGAAGAGATTTAGACTGGGAAAGAATGTTTGAATTATCTATAGATGAAGAAAAAGCCAGGAGATATAGAGAAGAA
TCTAAGGCAAAAAGTAAGGATTCTTGTACAATGTGCGGAAAAATGTGTGCAGTAAGAAATATGAACAGAGTTACAGAAGG
AAAAGACTTAAACATGTTAAGAGATGATGATTAA

Protein sequence :
MNYTTQMDAAKKGIVTKEMEIVAKKENMNVKDLMELVSKGKVAIPANKNHKSLDPEGIGQGLRTKINVNLGISKDCYNID
MELEKVQKAIDMKAEAIMDLSCFGKTEEFRKRLIDMSPAIIGTVPIYDAVGFYDKELKDITSEEFLKVAEKHVENGADFL
TIHVGMNRKTASTFKKNPRRMNIVSRGGSLLYAWMELNNKENPFYERFDELLDICEKYDVTLSLGDACRPGCIEDSTDAS
QIEELIALGELTKRAWDRNVQVIIEGPGHMTLDEIETNMKIEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAIAATH
GADFLCYVTPAEHLRLPNLDDMKEGIIATKIAAHAADLAKGVKGARDWDNAMAKARRDLDWERMFELSIDEEKARRYREE
SKAKSKDSCTMCGKMCAVRNMNRVTEGKDLNMLRDDD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 2e-69 44
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 2e-69 44
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 9e-67 42