Gene Information

Name : CLK_1760 (CLK_1760)
Accession : YP_001787695.1
Strain : Clostridium botulinum Loch Maree
Genome accession: NC_010520
Putative virulence/resistance : Virulence
Product : DNA-binding response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 2574218 - 2574898 bp
Length : 681 bp
Strand : -
Note : identified by match to protein family HMM PF00072; match to protein family HMM PF00486

DNA sequence : 
ATGGTTAAGATTTTAATAGTTGAAGATGAAGAGAAATTATCAAGATTTATTGAGCTTGAGTTAAAACACGAAGGGTATGA
AATAGTAAAAGCAGATAATGGTAGAACAGGTCTTGAAATTGCAGAAAAAGGTGAGATTGATTTAATTCTTCTTGATATAA
TGCTTCCAGAAATAAATGGTCTTGAAGTATTAAGAAGGCTTAGAAGAACTTCTGATATTCCAATTATAATGCTTACTGCA
AGAGATGCAGTTATGGATAAAGTATCAGGTCTTGATGCAGGAGCAGATGATTATATAACTAAGCCATTTGCAATAGAAGA
GTTACTTGCAAGAATAAGAACAGCCCTTAAAAAGAGAATAGTTACAGTGAAGAAAGATGAAGATATAATAAGATGTGGCT
TATTGTCATTAGATAAAATTAGACATAAAGTAATGTATGATAGCACAGAGATAGAACTAACAAATAGAGAGTTTAATTTG
TTACAAATATTAATGGAAAACAAGAATATAGTGTTAACTAGAAGTATACTTATGGAAAAGGTATGTGGTTATGATTATCT
TGGAGAAACCAATGTTATAGATGTTTATATAAGATTTTTAAGAACAAAAATAGATGATGCATTTAAGGTTAAAATAATAA
CTACAGTTCGTGGTGTGGGATACGTAATTAAAGATGAGTAG

Protein sequence : 
MVKILIVEDEEKLSRFIELELKHEGYEIVKADNGRTGLEIAEKGEIDLILLDIMLPEINGLEVLRRLRRTSDIPIIMLTA
RDAVMDKVSGLDAGADDYITKPFAIEELLARIRTALKKRIVTVKKDEDIIRCGLLSLDKIRHKVMYDSTEIELTNREFNL
LQILMENKNIVLTRSILMEKVCGYDYLGETNVIDVYIRFLRTKIDDAFKVKIITTVRGVGYVIKDE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 2e-38 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CLK_1760 YP_001787695.1 DNA-binding response regulator HE999704.1.gene1528. Protein 3e-47 56
CLK_1760 YP_001787695.1 DNA-binding response regulator NC_002951.3238224.p0 Protein 1e-46 52
CLK_1760 YP_001787695.1 DNA-binding response regulator NC_007793.3914065.p0 Protein 1e-46 52
CLK_1760 YP_001787695.1 DNA-binding response regulator NC_002758.1121390.p0 Protein 1e-46 52
CLK_1760 YP_001787695.1 DNA-binding response regulator NC_010079.5776364.p0 Protein 1e-46 52
CLK_1760 YP_001787695.1 DNA-binding response regulator NC_002952.2859858.p0 Protein 1e-46 52
CLK_1760 YP_001787695.1 DNA-binding response regulator NC_007622.3794948.p0 Protein 1e-46 52
CLK_1760 YP_001787695.1 DNA-binding response regulator NC_003923.1003417.p0 Protein 1e-46 52
CLK_1760 YP_001787695.1 DNA-binding response regulator NC_013450.8614146.p0 Protein 1e-46 52
CLK_1760 YP_001787695.1 DNA-binding response regulator AE015929.1.gene1106. Protein 3e-43 50
CLK_1760 YP_001787695.1 DNA-binding response regulator NC_012469.1.7685629. Protein 9e-39 44
CLK_1760 YP_001787695.1 DNA-binding response regulator BAC0308 Protein 1e-41 44
CLK_1760 YP_001787695.1 DNA-binding response regulator BAC0197 Protein 2e-41 44
CLK_1760 YP_001787695.1 DNA-binding response regulator BAC0125 Protein 3e-42 43
CLK_1760 YP_001787695.1 DNA-binding response regulator NC_005054.2598277.p0 Protein 3e-36 42
CLK_1760 YP_001787695.1 DNA-binding response regulator NC_014475.1.orf0.gen Protein 3e-36 42
CLK_1760 YP_001787695.1 DNA-binding response regulator BAC0111 Protein 3e-38 42
CLK_1760 YP_001787695.1 DNA-binding response regulator NC_012469.1.7686381. Protein 4e-34 41
CLK_1760 YP_001787695.1 DNA-binding response regulator BAC0347 Protein 5e-36 41
CLK_1760 YP_001787695.1 DNA-binding response regulator HE999704.1.gene2815. Protein 5e-37 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CLK_1760 YP_001787695.1 DNA-binding response regulator VFG0596 Protein 6e-39 41
CLK_1760 YP_001787695.1 DNA-binding response regulator VFG1390 Protein 3e-39 41