Gene Information

Name : CLK_1423 (CLK_1423)
Accession : YP_001787361.1
Strain : Clostridium botulinum Loch Maree
Genome accession: NC_010520
Putative virulence/resistance : Resistance
Product : DNA-binding response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 2215832 - 2216497 bp
Length : 666 bp
Strand : -
Note : identified by match to protein family HMM PF00072; match to protein family HMM PF00486

DNA sequence : 
ATGCCAAAGAGAATTCTTGTAGTAGAGGACGATTTTGATATACATACTATTATAAGTGAGGTTTTAAAGGAAAGTGGATA
TTTAGTAGAGGTTGCCACAGATGGATTAATTGCAGTGGAGATGTTTAGAAGGGGGGAATTTGATTTAATAATTTTAGATG
TGATGCTTCCTAAAATAGATGGATTTGTAGTATGTGAAATTATAAGAAAAGAATCAAGTATGCCTATAATAATGCTTACT
GCTCTGGGGGAAGAGGAAGATGAAATGAAAGGTTTTGAATTAAAAGTAGATGATTATATAATAAAACCTTTTTCTATTAA
TTTATTAATAAAAAGAGTAGAAGCAGTACTTAGAAGAGCCAATGGATTAGAGGAAAATAATTCAACTTTAACCTTTGAAG
AAATAACAATATATCCTTCTAATTATAAAACTTTGGTTAATAATAAGGAAATAGAACTAACTTATAAAGAATTTCAAATA
TTAGAAATATTAATATCAAATGTAGGAAGGGTCTTTTCTAGAGAATCTTTATTAAATCAAATATGGGGATATGATTATTT
TGGAGATACCCGTGTTATAGATACCCATATCAAAAATTTAAGACAAAAACTAAACATAGATTATATAAAAACCATAAGGG
GAGTGGGATATAAAATTGAGAAATAA

Protein sequence : 
MPKRILVVEDDFDIHTIISEVLKESGYLVEVATDGLIAVEMFRRGEFDLIILDVMLPKIDGFVVCEIIRKESSMPIIMLT
ALGEEEDEMKGFELKVDDYIIKPFSINLLIKRVEAVLRRANGLEENNSTLTFEEITIYPSNYKTLVNNKEIELTYKEFQI
LEILISNVGRVFSRESLLNQIWGYDYFGDTRVIDTHIKNLRQKLNIDYIKTIRGVGYKIEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanRB YP_008394254.1 DNA-binding response regulator VanRB Not tested Not named Protein 2e-43 44
vanRB NP_815956.1 DNA-binding response regulator VanRB Not tested Not named Protein 6e-43 43
vanRB YP_001698483.1 regulatory protein Not tested Not named Protein 1e-42 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CLK_1423 YP_001787361.1 DNA-binding response regulator HE999704.1.gene1202. Protein 1e-47 47
CLK_1423 YP_001787361.1 DNA-binding response regulator AF310956.2.orf0.gene Protein 8e-44 44
CLK_1423 YP_001787361.1 DNA-binding response regulator NC_002952.2859905.p0 Protein 1e-38 44
CLK_1423 YP_001787361.1 DNA-binding response regulator NC_002951.3237708.p0 Protein 1e-38 44
CLK_1423 YP_001787361.1 DNA-binding response regulator NC_003923.1003749.p0 Protein 1e-38 44
CLK_1423 YP_001787361.1 DNA-binding response regulator NC_002758.1121668.p0 Protein 1e-38 44
CLK_1423 YP_001787361.1 DNA-binding response regulator NC_009641.5332272.p0 Protein 1e-38 44
CLK_1423 YP_001787361.1 DNA-binding response regulator NC_013450.8614421.p0 Protein 1e-38 44
CLK_1423 YP_001787361.1 DNA-binding response regulator NC_007793.3914279.p0 Protein 1e-38 44
CLK_1423 YP_001787361.1 DNA-binding response regulator NC_007622.3794472.p0 Protein 1e-38 44
CLK_1423 YP_001787361.1 DNA-binding response regulator NC_002745.1124361.p0 Protein 1e-38 44
CLK_1423 YP_001787361.1 DNA-binding response regulator NC_009782.5559369.p0 Protein 1e-38 44
CLK_1423 YP_001787361.1 DNA-binding response regulator AE016830.1.gene2255. Protein 2e-43 43
CLK_1423 YP_001787361.1 DNA-binding response regulator U35369.1.gene1.p01 Protein 2e-43 43
CLK_1423 YP_001787361.1 DNA-binding response regulator NC_012469.1.7685629. Protein 5e-37 42
CLK_1423 YP_001787361.1 DNA-binding response regulator HE999704.1.gene2815. Protein 3e-37 41