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Name : secA (CLK_3351) Accession : YP_001785501.1 Strain : Clostridium botulinum Loch Maree Genome accession: NC_010520 Putative virulence/resistance : Unknown Product : preprotein translocase subunit SecA Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG0653 EC number : - Position : 200470 - 202977 bp Length : 2508 bp Strand : + Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap DNA sequence : ATGGGAATTTTAAATAAAATATTTGGTACATATAGTGAAAGAGAACTTAGAAGAGTTAACCCTATAGTAAACAAGATAGA AGCTTTAGATGAAAAAATGCAATCCTTAAAAGATGAAGATTTTAAGCTAAAAACTGAAGAATTTAAAAGTAGACTAGAAA AAGGGGAAAAATTAGATGATATCTTACCAGAAGCTTTTGCCTTAGTTAGAGAAGCGTCACATAGAACCATAGGACTTAAA CATTATAGAGAACAATTAATAGGCGGTGTAGTATTACACCAAGGAAGAATTGGAGAAATGAAAACCGGTGAAGGTAAAAC TTTAGTTGCTACATTGCCAGCCTATGTAAATGCATTAACAGGAAAAGGGGTACATATAGTTACAGTTAATGATTACTTGG CAAAAAGAGATAGAGATTTAATGGCTCCGGTATATGAATTTTTAGGGTTAAAAGTAGGAGTTATTTTGCATAATTTAAAT AATGAAGAAAGACAAGAAGCTTATGGTTCAGATATAACTTATGGAACAAATAGTGAATTTGGTTTCGATTATTTAAGAGA TAATATGGTAGTTTATAAAGAAGAAAGAGTTCAAAGAAAGTTAAACTTTTCAATTGTGGATGAAGTGGACTCTATATTAA TAGATGAAGCTAGAACTCCATTAATAATATCAGGTCAAGGAGAGAAGTCTACAGAGTTTTATAAGGTTGCAGATTATTTC ACTAAATCTCTAATAGCTGAAAAAGATTTTACAATAGATGAAAAAGCTAATTCAGCTATGCTTACAGATGAAGGTGTTAA TAAAGCAGAGAATTTCTTTAAAGTAGATAACTATGCTGATGCAGAAAACATGGAAATACAACACCATGTAGTTCAAGCTT TAAAAGCTAACTATGTAATGAAAAAAGATAAAGATTATATGATTAAGGATGGAGAAATTCTAATAGTTGATGAGTTTACA GGAAGAGCTATGGAAGGAAGAAGATATAGCGATGGATTGCACCAAGCTATAGAAGCTAAAGAAGGCGTTAGAGTAGAAAG AGAATCTAAAACTTTAGCTACAATAACTTATCAAAACTATTTTAGAATGTACAATAAATTGTCTGGTATGACAGGAACAG CTCAAACAGAAGAAAATGAATTTAGAGAAATCTATGGATTAGATGTAATTGTAATACCTACACATGAACCTATAGCAAGA ATAGATAATGCTGATGTAGTATATAAATCAGAAAAGGGTAAATTTAAAGCTATAGTTGATGAAATAGTAGAAAGATATAA AAAAGGTCAACCAATGCTAGTAGGTACAGTAAGCATAGAAAAATCAGAAATGTTATCCTCTATGTTAAAGAAAAAAGGAG TACCTCATCAAGTATTAAATGCTAAATATCATGAAAAAGAAGCGGAAATAATATCTCATGCAGGGGAATATGGGATGGTT ACAATAGCCACTAATATGGCAGGCCGTGGTACAGATATAAAACTTACTAAGGAAGCTGAAGAAGCAGGCGGGCTTATGAT TATAGGTACAGAAAGACATGAGTCTAGAAGAATAGACAACCAATTAAGAGGACGTTCTGGTCGTCAAGGAGATCCTGGTG AATCAAGATTTTTTGTATCTTTAGAAGATGATTTAATGAGAATATTTGGTTCAGAAAGAATACAAGGAATAGTTGATAAA TTAGGACTCGCTGAAGATGAAGCTATAGAAAGTAAAATGGTAAGTTCAGCTATAGAAAGTGCTCAAAAGAAGGTAGAAGG AAATAACTTTGATATAAGAAAAACTTTATTACAATATGATGATGTAATAAATAAGCAAAGAGAAATAATCTATAAACAAA GAAGTGAGGTTTTAGAGGGAGAAGACTTAAAGGATCAAATAAGAGATATGATAAGGGATGTGGCTTATACTGCAGTAAAT TCTCATGTTTCAGGAGTAGAAGAAGAGTTTGAAACAGAACTACAAAATCTTGTTAATTATTTAGAAGATATATGCTTACC AAAGGCCTTAGTAAAGGTAAAAGATATAAGTAATTTATCAGATGAAGAAATAAAAGAAAAATTATTAGAAGCAGTAGAGA ATATATATAGCAACAAAGAAAAAGAAATTGGGGAAGAACAAATAAGAGAAATAGAAAGAGTAATATTACTTAGGGTTGTA GATACTAAATGGATGGATCATATAGATGATATGGATCACTTAAAACAAGGTATAGGACTAAGAGCATATAGACAACAAGA TCCAGTTCAAGCATATCAATTTGAAGGTAGTGAAATGTTTGAGGAAATGATCTATAACATTAAAGTAGATACAGTAAGAT ATTTATTCCATGTGGAAGTAGAAAAAGCACCTGAAAGAGAGAAAGTAGCAAAAGAAACATCAACTAATTATGATGAGGAT TCAGTAAAAAAACAACCTATAAAAAAGGAAAATAGAATAGGTAGAAATGATATGTGTCCTTGTGGAAGTGGAAAAAAATA TAAAAATTGTTGTGGTAGAATGGCATAA Protein sequence : MGILNKIFGTYSERELRRVNPIVNKIEALDEKMQSLKDEDFKLKTEEFKSRLEKGEKLDDILPEAFALVREASHRTIGLK HYREQLIGGVVLHQGRIGEMKTGEGKTLVATLPAYVNALTGKGVHIVTVNDYLAKRDRDLMAPVYEFLGLKVGVILHNLN NEERQEAYGSDITYGTNSEFGFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYF TKSLIAEKDFTIDEKANSAMLTDEGVNKAENFFKVDNYADAENMEIQHHVVQALKANYVMKKDKDYMIKDGEILIVDEFT GRAMEGRRYSDGLHQAIEAKEGVRVERESKTLATITYQNYFRMYNKLSGMTGTAQTEENEFREIYGLDVIVIPTHEPIAR IDNADVVYKSEKGKFKAIVDEIVERYKKGQPMLVGTVSIEKSEMLSSMLKKKGVPHQVLNAKYHEKEAEIISHAGEYGMV TIATNMAGRGTDIKLTKEAEEAGGLMIIGTERHESRRIDNQLRGRSGRQGDPGESRFFVSLEDDLMRIFGSERIQGIVDK LGLAEDEAIESKMVSSAIESAQKKVEGNNFDIRKTLLQYDDVINKQREIIYKQRSEVLEGEDLKDQIRDMIRDVAYTAVN SHVSGVEEEFETELQNLVNYLEDICLPKALVKVKDISNLSDEEIKEKLLEAVENIYSNKEKEIGEEQIREIERVILLRVV DTKWMDHIDDMDHLKQGIGLRAYRQQDPVQAYQFEGSEMFEEMIYNIKVDTVRYLFHVEVEKAPEREKVAKETSTNYDED SVKKQPIKKENRIGRNDMCPCGSGKKYKNCCGRMA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| secA2 | YP_006310687.1 | preprotein translocase subunit SecA2 | Not tested | FWisland_3 | Protein | 5e-120 | 41 |
