Gene Information

Name : serS (CLK_3156)
Accession : YP_001785350.1
Strain : Clostridium botulinum Loch Maree
Genome accession: NC_010520
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 22336 - 23616 bp
Length : 1281 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATTTAAAAAGAATAAGAAATAATTCAAATGAAATAAAAGAAGCATTAAACAATAGAGGAGAAAAGTTTGATGT
AACTGTAATTGATGAAGTCTTAAAATTAGATGAAGAAAGAAGAAATATTTTAGTTAAAGTTGAGGTTTTAAAAAGTAAGA
GAAATCAAGTTTCTTCTGAAGTTCCTAAACTAAAAAAAGAAGGAAAAGATGTATCTAATATAGTAGCTGAAATGAAAAAT
TTATCAGAAGAAATAAAAGGGTTTGATACTACTTTAGCTAAAATAGATGAAAAAATACAATATATAATGCTTAGAATACC
TAATATACCAAACCCACAAGTTCCAGATGGAGAAACAGATGAGGATAATATAGAAATAAGAAATTGGTCAGAACCAACAA
AATTTGATTTTGAGCCTAAAGCACATTGGGATATAGGTTCAAATTTAAATATTCTTGATTTTGAAAGAGCTGGAAAAGTA
ACAGGATCAAGATTTACTTTTTATAAAGGATTAGGAGCTAGATTAGAAAGATCATTAATATCCTATTTTCTAGATACTCA
TACAGAGAAGCATGGATACACTGAAATATTACCACCTTATATGGTGAATAGAACAAGTATGATAGGAACAGGACAATTAC
CTAAATTTGAAGAAGATGCTTTTAAAATTTCAGAGGATGATTACTTCTTAATACCAACTGCAGAGGTTCCTGTAACTAAT
TTATACAGAGATGAAATCTTAAAAGGTGATGAATTACCATTAAAACATGTAGCTTATAGTGCTTGTTTTAGATCAGAAGC
CGGTTCAGCAGGTAGAGATACAAGAGGTCTTGTTAGACAGCATCAATTCAATAAAGTAGAGCTTGTTAAATTTACAAAAC
CAGAACAGTCTTATGAAGAATTAGAAAAATTAACTAATGATGCTGAAACAGTATTAAAAGAGTTAGGTATTCCATATAGG
GTTGTAAGAATATGTAAAGGTGATTTAGGATTTACAGCTGCATTAAAATATGATTTAGAAGTTTGGATGCCAAGTTACAA
TAGATATGTTGAAATATCAAGCTGTAGTAACTTTGAAGACTTCCAAGCAAGACGTGCTAATATAAGATATAAAGAAGATG
CAAAAGCAAAACCACAATATGTTCATACATTAAATGGATCAGGAGTTGCTATTGGAAGAACTGTTGCAGCTATACTTGAA
AACTATCAAAATGAAGATGGATCAGTTACAATACCAGAAGTGTTAAGACCTTATATGGGAGGAAAAGAAGCAATAAAATA
G

Protein sequence :
MLDLKRIRNNSNEIKEALNNRGEKFDVTVIDEVLKLDEERRNILVKVEVLKSKRNQVSSEVPKLKKEGKDVSNIVAEMKN
LSEEIKGFDTTLAKIDEKIQYIMLRIPNIPNPQVPDGETDEDNIEIRNWSEPTKFDFEPKAHWDIGSNLNILDFERAGKV
TGSRFTFYKGLGARLERSLISYFLDTHTEKHGYTEILPPYMVNRTSMIGTGQLPKFEEDAFKISEDDYFLIPTAEVPVTN
LYRDEILKGDELPLKHVAYSACFRSEAGSAGRDTRGLVRQHQFNKVELVKFTKPEQSYEELEKLTNDAETVLKELGIPYR
VVRICKGDLGFTAALKYDLEVWMPSYNRYVEISSCSNFEDFQARRANIRYKEDAKAKPQYVHTLNGSGVAIGRTVAAILE
NYQNEDGSVTIPEVLRPYMGGKEAIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 6e-129 61