Gene Information

Name : lysS (HSM_0524)
Accession : YP_001783868.1
Strain : Haemophilus somnus 2336
Genome accession: NC_010519
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 600962 - 602470 bp
Length : 1509 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGACAGAAATAATTCAAGAATTGGATCTCAATGGCGAAATGTTGGTTCGTCGTGAAAAATTAGCTGCGTTAAGAGCAAA
AGGCAACGCCTTTCCAAATACATTCCGTCGCAATGCTTTAGCACAGGACTTACATACACAATATGATGAAATTGAAAGTG
AGAGCTTAAAAACACAGGGAATTGAAGTAAAAGTGGCGGGGCGTATTATGACTCGTCGTGTCATGGGTAAAGCAACCTTT
ATCACATTGCAAGACATGAGCGGAAAAATTCAACTTTATGTTGCTCGTGATAACCTAGCTGAAGGTGTTTATACTGATGA
TGTGGGCAATTGGGATTTAGGGGATATTGTTGGTGTAAAAGGTACTTTATTTAAAACTAAAACCAATGAGTTGACAATAC
GTGCAACGGAAGTTCACTTATTAACTAAAGCATTACGCCCGCTTCCTAATAAATTTCATGGACTGAGCGATCAAGAAACT
CGTTACCGTCAACGCTACTTAGATTTAATTGCTAATGAAGATTCACGCCGCACTTTTATTATTCGATCTAAAGTAATCGC
AGGCATTCGTGAATATTTCATTTCCAAGGGATTTATGGAAGTAGAAACCCCTATGTTACAAATTATTCCGGGTGGTGCAT
CTGCACGTCCATTTATTACTCATCACAATGCGTTAGATGTGGATATGTATTTACGTATTGCACCTGAACTTTATTTAAAA
CGTTTGGTAGTTGGCGGTTTTGAACGTGTATTCGAGTTAAATCGTAACTTCCGCAATGAAGGTGTTTCTATTCGCCATAA
CCCTGAATTTACTATGTTGGAATACTACCAAGCCTATGCGGATTACCACGATTTAATGGACAATACAGAAGAACTTTTAC
GCAAATTAGCACTGGATATTTTAGGTACGACCATTGTTCCTTACGGCGATTTAAAATTCGATTTCGGCAAACCGTTTGAA
CGTATTACCATGCACGAGGCAATCTTAAAATACGGTGCCGAGCAAGGTATTGTGAAAGAAGATTTATACGATTTCGATCG
TGCTGTTGCAGTAGCACAAAAATTGGGTATCGAAGTACAAAAATCATGGGGGCTAGGTAGCTTAGTCAATGCAATTTTTG
AAGAAGTTGCTGAACATCATTTAATTCAACCAACTTTCTTAATGGCTCATCCGGCAGAAATCTCCCCTTTAGCACGCCGC
AATGATGAAAATCCTGACGTAACAGACCGCTTTGAATTATTTATCGGAGGACGTGAGATCGGTAACGGTTTCTCAGAATT
AAATGATGCAGAAGATCAAAATGAGCGTTTTGATGCACAGGTTGCAGCAAAAGAAGCTGGTGACGATGAAGCTATGTTTA
AAGATGAAGATTTTGTTACCGCACTTGAGCATGGATTGCCACCAACGGCTGGTGAGGGTTTAGGAATTGATCGTCTAGCG
ATGTTATTTGCCAACGCTAACTCAATTCGTGATGTAATTTTATTTCCAGCAATGAAAACAAAAAGTTAA

Protein sequence :
MTEIIQELDLNGEMLVRREKLAALRAKGNAFPNTFRRNALAQDLHTQYDEIESESLKTQGIEVKVAGRIMTRRVMGKATF
ITLQDMSGKIQLYVARDNLAEGVYTDDVGNWDLGDIVGVKGTLFKTKTNELTIRATEVHLLTKALRPLPNKFHGLSDQET
RYRQRYLDLIANEDSRRTFIIRSKVIAGIREYFISKGFMEVETPMLQIIPGGASARPFITHHNALDVDMYLRIAPELYLK
RLVVGGFERVFELNRNFRNEGVSIRHNPEFTMLEYYQAYADYHDLMDNTEELLRKLALDILGTTIVPYGDLKFDFGKPFE
RITMHEAILKYGAEQGIVKEDLYDFDRAVAVAQKLGIEVQKSWGLGSLVNAIFEEVAEHHLIQPTFLMAHPAEISPLARR
NDENPDVTDRFELFIGGREIGNGFSELNDAEDQNERFDAQVAAKEAGDDEAMFKDEDFVTALEHGLPPTAGEGLGIDRLA
MLFANANSIRDVILFPAMKTKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 6e-154 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001783868.1 lysyl-tRNA synthetase VFG1668 Protein 3e-154 64