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Name : leuS (HSM_0467) Accession : YP_001783813.1 Strain : Haemophilus somnus 2336 Genome accession: NC_010519 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 542393 - 544975 bp Length : 2583 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGCAAGAACAATATCGTCCTGATCTTATCGAAGCAGACGTACAGAAATATTGGGCTGAAAAGAAAACATTCAAAGCCGT TAAAGATCCTTTCAAAGAAAAATATTATTGTCTTTCCATGTTTCCTTATCCTTCCGGTCGTTTACACATGGGGCATGTTC GTAACTATACCATTGGCGATGTTATCTCCCGTTATCAACGAATGAACGGTAAAAATGTTTTACAGCCTATGGGCTGGGAT GCTTTTGGGTTGCCAGCAGAAGGTGCGGCAATTAAAAATAAAACCGCACCGGCAAAATGGACTTATGAAAATATCGAATA CATGAAAAATCAGCTTAAAGTGTTGGGCTTCGGATTTGATTGGGATCGTGAAATTACCACTTGTAAACCTGAATATTATA AATGGGAGCAATGGTTTTTTACTGAGTTGTACAAAAAAGGATTGGTTTATAAAAAAACCTCAACAGTAAACTGGTGTCCG AATGATGAAACCGTTTTAGCAAATGAGCAAGTACATGAGGGGGGTTGTTGGCGTTGCGATACCCCTGTGGAGCAAAAAGA AATTCCGCAATGGTTTATTAAAATTACGGACTATGCTGAACAATTATTAAGTGATTTAGATCAGCTTCCTGAATGGCCGG ATATGGTAAAAACTATGCAACGTAACTGGATAGGTCGCTCCGAAGGGGTTGAAATTACCTTTAACGTTGCTCATTCAGAT CAAACCTTAACAGTTTATACAACTCGTCCGGATACTTTCTATGGTGTTTCTTATTTAGCGGTTGCAGCGGCACATCCGTT AGCTGAAAATGCGGCAAAAAATAATCCTGAATTGGCTGCTTTTATTCACGAGGCAAAAAATACCAAAGTGGCTGAAGCGG AACTTGCTACAATGGAGAAAAAAGGCATGGCAACAGGATTGTATGCAGTTCATCCGATGACAGGTAAACAGTTACCGATT TGGGTAGCAAATTTTGTGTTAATGCACTACGGTACAGGTGCGGTTATGGCAGTTCCTGCACATGATCAACGTGATTATGA ATTTGCACAAAAATATCAATTGCCTTTATTCCCCGTGATTAAGCCGGCGGATAATTCTGCATGGGATTTTTCAAAACAGG CTTATACTGAGCATGGTATCACCATTAATTCTGCTGAGTTTGACGGTTTGGATTTTGAGGCAACCTTTAACGGTATTGCG GATAAACTTGAAAAAATCGGTGTAGGAAAACGCCAAGTAAACTATCGTTTACGTGACTGGGGAGTTTCCCGTCAACGTTA TTGGGGAGCACCAATTCCAATGCTGACACTGGAAAATGGTGATGTTGTAGTTGCCCCATTACAGGACTTACCAATTGTTT TGCCGGAAGATGTAGTCATGGACGGAGTAAAAAGTCCGATTAAGGCTGATCCTGAATGGGCAAAAACCACTTATAACGGA CAAGTAGCATTAAAAGAAACGGATACCTTTGATACTTTCATGGAATCTTCTTGGTACTATGCACGCTATACCTCTCCACA ATATCAACAAGCGATGTTAGATGCAGATGAAACGAATTATTGGCTACCGGTGGATCAATATATTGGTGGCATTGAACATG CAACCATGCACCTATTATATTTCCGTTTCTTTCACAAATTGTTGCGAGATGCCGGTTTCGTAACTTCTGATGAGCCAAGC AAAAAATTACTGTGTCAAGGTATGGTACTTGCAGACGCATTTTATTACACCAGCCCAACCAATGAGCGTATTTGGGTATC GCCGACAAAAGTAACGTTAGAGCGTGATGAGAAAGGTCGTATTATCAAAGCTGTTGATGATGAAGGTCACGAGCTTGTTC ACAGCGGTATGACCAAAATGTCTAAGTCCAAAAATAATGGTATTGATCCGCAAGAAATGGTGGAGAAATACGGTGCAGAT ACAGTCCGTTTATTTATGATGTTTGCTTCACCGGCAGAAATGACACTTGAATGGCAAGAGTCAGGAGTAGAGGGGGCAAA TCGTTTCTTACGCCGCCTATGGAATTTAGTTTTTGAATACAATCAAAATCCGGCACAAACCGCATTAGATCCTACCGCTC TTTCAGTCGAACAAAAAGCATTGCGTCGTGAGGTACATAAAACTATTGCAAAAGTGAGCGATGATATTGGTCGTCGCCAA ACATTCAATACCGCAATTGCGGCAATCATGGAATTAATGAATAAACTCACCAAAGCATCATTATCCAATGAGCAAGATCG TGCAGTAATGGCGGAAGCATTGAATGCCGTTGTGCGTATGCTTTATCCGATTACACCACATATTTGTTTCCAACTTTGGC AAGACTTAGGTAACGAAAGTGCGATTGATTTTGCACCTTGGGTGATAGCCGATGCTGAAGCTATGGTTGAAGATGAAAAA TTGGTTGTGATACAAGTGAATGGTAAAGTTCGTGCTAAAGTAACCGTTCCTGCTGATATGTCGGAAGATGAAATTAAACA AGTTGCTTTAGCAGAAGAAAATGTACAAAAATTCTTGAATGGTTTAACTGTAGTTAAGACCATTTATGTACCGGGTAAAT TATTTAGCTTTGTAGCAAAATAA Protein sequence : MQEQYRPDLIEADVQKYWAEKKTFKAVKDPFKEKYYCLSMFPYPSGRLHMGHVRNYTIGDVISRYQRMNGKNVLQPMGWD AFGLPAEGAAIKNKTAPAKWTYENIEYMKNQLKVLGFGFDWDREITTCKPEYYKWEQWFFTELYKKGLVYKKTSTVNWCP NDETVLANEQVHEGGCWRCDTPVEQKEIPQWFIKITDYAEQLLSDLDQLPEWPDMVKTMQRNWIGRSEGVEITFNVAHSD QTLTVYTTRPDTFYGVSYLAVAAAHPLAENAAKNNPELAAFIHEAKNTKVAEAELATMEKKGMATGLYAVHPMTGKQLPI WVANFVLMHYGTGAVMAVPAHDQRDYEFAQKYQLPLFPVIKPADNSAWDFSKQAYTEHGITINSAEFDGLDFEATFNGIA DKLEKIGVGKRQVNYRLRDWGVSRQRYWGAPIPMLTLENGDVVVAPLQDLPIVLPEDVVMDGVKSPIKADPEWAKTTYNG QVALKETDTFDTFMESSWYYARYTSPQYQQAMLDADETNYWLPVDQYIGGIEHATMHLLYFRFFHKLLRDAGFVTSDEPS KKLLCQGMVLADAFYYTSPTNERIWVSPTKVTLERDEKGRIIKAVDDEGHELVHSGMTKMSKSKNNGIDPQEMVEKYGAD TVRLFMMFASPAEMTLEWQESGVEGANRFLRRLWNLVFEYNQNPAQTALDPTALSVEQKALRREVHKTIAKVSDDIGRRQ TFNTAIAAIMELMNKLTKASLSNEQDRAVMAEALNAVVRMLYPITPHICFQLWQDLGNESAIDFAPWVIADAEAMVEDEK LVVIQVNGKVRAKVTVPADMSEDEIKQVALAEENVQKFLNGLTVVKTIYVPGKLFSFVAK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 2e-159 | 41 |
