Gene Information

Name : HSM_0277 (HSM_0277)
Accession : YP_001783628.1
Strain : Haemophilus somnus 2336
Genome accession: NC_010519
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 298438 - 299547 bp
Length : 1110 bp
Strand : +
Note : catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity

DNA sequence :
ATGACACAACAATATGCTCTAGATACATTACTGGCTCAGGCAGGTAATAGAACAGATGAAAGAACCGGTGCGGTATCTAC
GCCGATTTTTCTTTCCACTGCTTATGCTCATCATGGAATTGGTGAAAGTACGGGATTTGATTATACCCGCACTAAAAATC
CAACGAGAACGGTATTAGAAGAAACAATTGCAAAATTAGAAGGTGGAGATCGTGGATTTGCCTGTTCTTCAGGAATGGCG
GCTATTCAATTATTGATGAACTTATTTGCGTCACCTGATGAATGGATTGTTTCCAGCGATGTTTATGGCGGAACTTATCG
CCTATTGGATTTTGCACATAAGAATATTCATGGTGTCAAACCTGTTTATGTCAATACAGCTTCAAGTGAAGAAATTGAAA
AGGCAATCACTGAGAATACAAAGGCGATTTTTGTTGAAACACCATCGAATCCGTTAATGGAAGAATGTGATGTGGCAGAA
ATTGCGAAAATAGCTAAAAAATACAATTTGCTATTGATTGTAGACAATACTTTTTTAACTCCTGTTTTATTTAGACCAAT
GGAACATGGTGCAGATATTGTTATTCATAGTGGAACAAAATATATTGCTGGTCATAATGACACATTAGTAGGGTTAATTG
TTGCCAAAGGGCAAGAGATCTGTGACCGCTTATATTATATTCAAAATGGTGCAGGTCCCGTATTATCACCTTTTGATTCT
TGGTTGACCATTCGAGGCATGAAGACACTTGCATTGCGAATGGAACGTCATCAGAAAAATGCACAGGAATTGGCAAACTT
TTTAAGAGAACAGCCACAAGTAAAAGATGTGTTATATCCAAATAAAGGAGGGATGCTATCTTTTCGTCTTCAAAATGAAA
ATTGGGTAAATCCTTTTCTTAAAGCAATGAAGTTAATTACTTTTGCTGAGAGTTTAGGCGGTACGGAAAGTTTCATTACG
TATCCGGCGACACAAACGCATATGGATATTCCTGAGGTTGAACGTGTTGCTCGAGGTGTATGCAATCGTTTACTACGGTT
TTCTGTAGGATTGGAGAATGTAGAAGATATTAAAGCGGATTTATTGCAGGCATTTTCTCAACTAAAGTAA

Protein sequence :
MTQQYALDTLLAQAGNRTDERTGAVSTPIFLSTAYAHHGIGESTGFDYTRTKNPTRTVLEETIAKLEGGDRGFACSSGMA
AIQLLMNLFASPDEWIVSSDVYGGTYRLLDFAHKNIHGVKPVYVNTASSEEIEKAITENTKAIFVETPSNPLMEECDVAE
IAKIAKKYNLLLIVDNTFLTPVLFRPMEHGADIVIHSGTKYIAGHNDTLVGLIVAKGQEICDRLYYIQNGAGPVLSPFDS
WLTIRGMKTLALRMERHQKNAQELANFLREQPQVKDVLYPNKGGMLSFRLQNENWVNPFLKAMKLITFAESLGGTESFIT
YPATQTHMDIPEVERVARGVCNRLLRFSVGLENVEDIKADLLQAFSQLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-64 42
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-65 41