Gene Information

Name : hemC (HSM_1937)
Accession : YP_001785251.1
Strain : Haemophilus somnus 2336
Genome accession: NC_010519
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2194814 - 2195779 bp
Length : 966 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAGTATCAACAAGACCCTAAAAATTGCGACACGTCAAAGTCCGTTAGCATTATGGCAGGCAAATTACGTTAAAAATCG
CCTACAACAACGTTATTCTCATTTAAGTGTCGAACTTGTCCCTATCATCACAAAAGGCGATGTTATCTTAGATACACCTT
TAGCTAAAATTGGCGGAAAGGGATTATTTGTAAAAGAATTAGAAAATGCGTTGTTAAATGGTGAAGCGGATATTGCGGTG
CATTCGATGAAAGATGTGCCAATGCAATTTCCGAAAGGATTAGAGCTAAGTGTGATTTGTCCGAGAGAGGATCCTCGTGA
TGCATTTGTTTCAAATAAGTACCGCACTTTAGACGAGTTACCGCAAGGTGCTATTGTAGGAACATCGAGTTTACGTAGGC
AATGTCAACTCAAAAACTGGCGAGCGGATCTCGATATCCGTTCTTTACGTGGTAATGTTGGAACAAGATTAAATAAGTTA
GATCAGGGTGATTATGATGCGATTATCTTAGCTTCGGCAGGATTAATTCGGTTAGGATTGACTGAACGTATTCGCTCTTT
TATTGAAATTGATACGATTTTACCTGCTTGTGGACAAGGTGCGGTAGGAATTGAGTGTCGGGTAGATGATCGAGATGTGC
AATCTTTATTGATGCCGTTGGCTGATCAGACGACAACTTATTGCGTATTGGCAGAGCGTGCAATGAATTTTCATTTGCAA
GGTGGTTGCCAAGTTCCGATTGGTGCTTATGCAATTTTAGAGAATAATCAGTTATATTTGCGTGGTTTAGTGGGAGATGT
TCACGGTTCACAAATTCTATCGGCAGAAGGGCAATTTGAATTATCTCTTGATTTTGAATCATCGCAAAGTGCGGTGCAAA
AAGCGGAAGAATTAGGCGTGAGTATTGCTGAACAATTATTACAGCAAGGTGCAGATAAAATCTTACAGGCTGTTTATCAA
TCATAA

Protein sequence :
MSINKTLKIATRQSPLALWQANYVKNRLQQRYSHLSVELVPIITKGDVILDTPLAKIGGKGLFVKELENALLNGEADIAV
HSMKDVPMQFPKGLELSVICPREDPRDAFVSNKYRTLDELPQGAIVGTSSLRRQCQLKNWRADLDIRSLRGNVGTRLNKL
DQGDYDAIILASAGLIRLGLTERIRSFIEIDTILPACGQGAVGIECRVDDRDVQSLLMPLADQTTTYCVLAERAMNFHLQ
GGCQVPIGAYAILENNQLYLRGLVGDVHGSQILSAEGQFELSLDFESSQSAVQKAEELGVSIAEQLLQQGADKILQAVYQ
S

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-83 60
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-83 60