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Name : HSM_1720 (HSM_1720) Accession : YP_001785040.1 Strain : Haemophilus somnus 2336 Genome accession: NC_010519 Putative virulence/resistance : Unknown Product : DNA topoisomerase III Function : - COG functional category : L : Replication, recombination and repair COG ID : COG0550 EC number : 5.99.1.2 Position : 1963256 - 1965307 bp Length : 2052 bp Strand : - Note : decatenates replicating daughter chromosomes DNA sequence : ATGAAATTATTTATTTGTGAAAAGCCATCTCAAGCTCGAGATCTTGCCGGCGTATTGGGTGCTACTTCAAAAGGTGAAGG CTTGCTGGCGACTGCGGATAAATCTATTATTGTCACTTGGGGGTTCGGGCATCTCGTTGAGCAATATCAGCCGGAAGATT ATGATGAAGCGTGGAAACGCTGGGCATTTGAAACATTACCCATTATTCCTGCTCAGTGGAAAATGACACCGAAAAAAGAG TCTAAGAAGCAATATTCTGTTGTAATAGGGCTTATCAAAAAAGCAACCTCCGTGGTCATTGCGACCGATGCTGATCGAGA AGGTGAGATGATTGCTCGTGAGCTGTTAGATTTAGCTGGATACCGAGGTCAAATCCAACGTTGCTGGCTATCAGCTCTGG ATGATGCCAGTATTCGAAAGGCTCTTCAAACACTCAAATCAGGTAAAGAAACCGAGGCTCTTTACTACGCCGGTATGGGA CGTAGCCGCTCGGACTGGTTGATTGGAATGAACTTCTCCCGTTTATTTACCTTAATGGCTCAAGCAAAAGGCTATTCCGG TAAGCCATTGAGCGTTGGTCGAGTACAAAGTCCAACATTAACTCTTGTGGTTAATCGAGATAGAGAAATTGCTAATTTCG TGCCTAAATCTCATTATGCGTTAGCGGTTCAGCTGACAACAACCTCTGGTGAAACTTTCGTTGCCGGGCTTGCAGTACCT GAACAGTATTTGGATGAGTCCGGACTTTGCCTTGATAGTCGTGTCATACAACAAGCCGAAGCTCAAATTAAACAAACAGG CTTAGCCAAAGTGGTGACGGTTGAAACTAAACGAGAGAAAAAATCTCCACCGTTACTCTACGCATTAAGTGATTTACAAG GCGAATGTAACCGCTTGTTTGGCTTTGGGGCTCAGCAGGTGTTGGATATCGCACAATCCCTTTACGAAGAGCATAAAATC ACGACTTATCCCCGTACAGACTGTGGTTATCTGCCAGAATCACAATTTTCTGATGTTCCTAACGTAATCCGCTCATTAGT TGCCTCTGATTCAGGGCTACAAACTCTCTTGCCTAAATTAAATTTGCGACAAAAAAGTCGGGCGTGGGACGATAAAAAAA TTACCGCTCACCACGGTATTATCCCAACCATTAAAAAAGCTGATTTAAGTAAATTGAGTGAGGAGGAAATGAAGGTCTAT GATCTCATTCGCCGCCGATATCTTGCTCAATTCTTACCGCACTTGGAAATGGATAAAACCGTTGCCACTCTGCAATCTAG TGGGCACACTCTGGTTGCTCGGGGAAATGTCATCGTTGCTCAAGGCTGGCGTATCTTGTTTGGCAAAAATGTGGATGAGG AAACTGGTAATGATGATGAGAAACAAGGATTACCTGTATTGACTAAAAATCAGCAATGCAATGTCACTCATTCTGAAGTC CGAACATTGCAAACTAAACCTCCCGCACACTATACAGAGGGGACATTACTCGATGCAATGAAAAATGCCGCTCGCTTTGT GACTGACCCAAGACTCAAACAACGCTTACGTGAAACGGAAGGTTTAGGCACAGAAGCAACCCGTGCCGGATTAATTCAAG GCCTAATTGACAAAGGATTTCTCCTTAAGAAGAAAAAATCACTGGTTGCCTCAGCAGAAGCCGTTGCCTTAATTGATAGT TTGCCGGACTTACTGAAAAATCCCGGTTTAACGGCATTATGGGAACAAGCCCTCAATCAGATTGCCGAAGGTAGTATGAC ACTTGATGCATTTATGCAAAAGCAAGAAGCATTTGTAAAACAACTTATCGGCAGTTGTATGCAACAGGGAATGTCACTTG GGAATATTGAAATCCGAAAATGTTCAGAATGTGGTAAGCCAATGAGAAAAATCAATCACGCTAAGGGAACATTCTGGGGA TGTACTGGTTATCCAGATTGCCAACATAAAGAGGCTGATAAAAAGGTAAAATCAGCTTCAAATAAATCTGCTAAGAAAAG TAGTAATTTAAATGTACTCGATCAACTGAATAAATTAAGAAGCCAGTTATAA Protein sequence : MKLFICEKPSQARDLAGVLGATSKGEGLLATADKSIIVTWGFGHLVEQYQPEDYDEAWKRWAFETLPIIPAQWKMTPKKE SKKQYSVVIGLIKKATSVVIATDADREGEMIARELLDLAGYRGQIQRCWLSALDDASIRKALQTLKSGKETEALYYAGMG RSRSDWLIGMNFSRLFTLMAQAKGYSGKPLSVGRVQSPTLTLVVNRDREIANFVPKSHYALAVQLTTTSGETFVAGLAVP EQYLDESGLCLDSRVIQQAEAQIKQTGLAKVVTVETKREKKSPPLLYALSDLQGECNRLFGFGAQQVLDIAQSLYEEHKI TTYPRTDCGYLPESQFSDVPNVIRSLVASDSGLQTLLPKLNLRQKSRAWDDKKITAHHGIIPTIKKADLSKLSEEEMKVY DLIRRRYLAQFLPHLEMDKTVATLQSSGHTLVARGNVIVAQGWRILFGKNVDEETGNDDEKQGLPVLTKNQQCNVTHSEV RTLQTKPPAHYTEGTLLDAMKNAARFVTDPRLKQRLRETEGLGTEATRAGLIQGLIDKGFLLKKKKSLVASAEAVALIDS LPDLLKNPGLTALWEQALNQIAEGSMTLDAFMQKQEAFVKQLIGSCMQQGMSLGNIEIRKCSECGKPMRKINHAKGTFWG CTGYPDCQHKEADKKVKSASNKSAKKSSNLNVLDQLNKLRSQL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| topB1 | YP_005176228.1 | DNA topoisomerase III | Not tested | ICEPmu1 | Protein | 0.0 | 100 |
| pph56 | CAI36097.1 | Topoisomerase IA | Not tested | PPHGI-1 | Protein | 4e-155 | 51 |
| topB | AAF14809.1 | topoisomerase B | Not tested | SPI-7 | Protein | 9e-150 | 50 |
| topB | NP_458624.1 | topoisomerase B | Not tested | SPI-7 | Protein | 1e-149 | 50 |
| topB | NP_807836.1 | DNA topoisomerase III | Not tested | SPI-7 | Protein | 1e-149 | 50 |
| topB | AAN62194.1 | putative DNA topoisomerase III | Not tested | PAGI-2(C) | Protein | 3e-157 | 50 |
| topB | AAN62317.1 | putative DNA topoisomerase III | Not tested | PAGI-3(SG) | Protein | 7e-151 | 49 |
| PMI2630 | YP_002152332.1 | DNA topoisomerase III | Not tested | Not named | Protein | 1e-139 | 47 |
