Gene Information

Name : HSM_1109 (HSM_1109)
Accession : YP_001784439.1
Strain : Haemophilus somnus 2336
Genome accession: NC_010519
Putative virulence/resistance : Virulence
Product : N-acetylmannosamine kinase
Function : -
COG functional category : K : Transcription
COG ID : COG1940
EC number : -
Position : 1271198 - 1272076 bp
Length : 879 bp
Strand : -
Note : catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein

DNA sequence : 
ATGCGTTGCTTAGCAATTGATATTGGCGGTACAAAAATTGCAACCGCTGTTGTTGAAGAAAAGAAGCTCTCTAACCGTCA
GCAAATCAGCACGCCACAAGCAGATCCTACAGTCGCATTGCATCATGCCATCGAGCAAATTATGCAAAGTTATTCGGGAC
AGTTTGATGCGGTTGCGGTTGCATCGACAGGCATCATCAACAACGGTATTTTAACCGCACTTAATCCTAAAAATCTCGGT
GGACTGGTTGATTTCCCCTTACAAAAAAGCATTGCTCTCCATACAGATAAACCGATTGGCTTGCTAAATGATGTACAGGC
TGCTGTTTGTGCAGAGTACCAAGATCAAGACCAAAGTGCGGTACGAAATTTTATTTTTATCACGGTATCAACTGGCGTTG
GCGGAGGAATTATTCTTGATGGAAAATTATCCACTGGGCTAAATGGTATAGCTGGTCATATCGGGCATACTTTGGCAGAT
CCGAACGGTCCAATTTGTGGTTGCGGTCGTCGTGGTTGTGTTGAAGCGATTGCGGCGGGGCGAGCAATTGAACGTGAGGC
GAATAAGTGGGAAAAGCCTTGTAATCCGAAAGAAGTGTTCAACTTGTTCCGTAAAAATGATGAAAAAGCAACCGCACTTG
TTCGATCCTCAGCAAAAGCTATTGCTAACTTAATTGCTGATATGGTGATTAGTTTAGATGTGCAAAAGGTTGTTTTAGGC
GGTAGCGTTGGATTAGCTGAGGGATACTTATCCCTCGTTCAAGAATATTTAACCGACATGCCAAAATTTTATCACTGTAT
TTTGGAGCCGGCTAAATACGGTGCCGATGCAGGTTTAATTGGTGCGGCTTATTGGATGAAAATGCAACAAACCCCATAA

Protein sequence : 
MRCLAIDIGGTKIATAVVEEKKLSNRQQISTPQADPTVALHHAIEQIMQSYSGQFDAVAVASTGIINNGILTALNPKNLG
GLVDFPLQKSIALHTDKPIGLLNDVQAAVCAEYQDQDQSAVRNFIFITVSTGVGGGIILDGKLSTGLNGIAGHIGHTLAD
PNGPICGCGRRGCVEAIAAGRAIEREANKWEKPCNPKEVFNLFRKNDEKATALVRSSAKAIANLIADMVISLDVQKVVLG
GSVGLAEGYLSLVQEYLTDMPKFYHCILEPAKYGADAGLIGAAYWMKMQQTP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nanK YP_002414055.1 N-acetylmannosamine kinase Not tested Not named Protein 4e-28 45
VC1782 NP_231417.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 2e-29 43
VC0395_A1379 YP_001217322.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 2e-29 43
VPI2_0030 ACA01847.1 ROK family protein Not tested VPI-2 Protein 1e-28 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HSM_1109 YP_001784439.1 N-acetylmannosamine kinase VFG1115 Protein 1e-29 43