Gene Information

Name : HSM_0998 (HSM_0998)
Accession : YP_001784328.1
Strain : Haemophilus somnus 2336
Genome accession: NC_010519
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 1136595 - 1137365 bp
Length : 771 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGAATTTCACGGTTATTATTCCCGCACGTTATGCGTCCAGTCGCTTACCGGGTAAACCTTTGGCTGACATTGCTGGAAA
ACCAATGATCCAACACGTTTGGGAAAAAGCACAACAATCCGGTGCAACAAGAGTGGTCGTTGCAACAGATTATGAGGAAG
TTGCACGAGCAGTTCGTGGTTTTGATGGAGAAGTTTGTATGACTTCCTCTCAGCATAATTCAGGTACAGAACGTTTGGCT
GAAGTGATAGAAAAATTAGCTGTACCTGATGATGAAATTATTGTGAATATTCAAGGTGATGAGCCTCTTATTCCCCCTGT
TATTGTGAGTCAAGTTGCACAAAATCTACAAAAATATCAAGTGAATATGGCAACTCTTGCAGTAAAAATTGAAGATGTGG
AAGAGTTATTTAATCCAAATGTAGTGAAAGTTTTAACAGATAAAGATGGTTATGTTTTATATTTTTCTCGTGCAGTTATT
CCATGGGATCGAGATCAGTTTGTTCAACTGGGTAAAGCAGATTTATCTCAATTGCAATTGCACCAACATTATTTCCGTCA
TATTGGTATTTATGCTTATCGTGCCGGCTTTATTAAACAATATGTACAATGGCAACCCACAACATTGGAACAAATTGAAA
GACTTGAACAATTGCGTGTCCTTTGGAACGGTGAAAGAATTCATGTGGAATTAGCAAAACAAGCTCCTGCCGTTGGGGTA
GATACGGTAGAAGATTTAGAAAAAGTGCGGTCTATTTTATCTCATGTTTGA

Protein sequence : 
MNFTVIIPARYASSRLPGKPLADIAGKPMIQHVWEKAQQSGATRVVVATDYEEVARAVRGFDGEVCMTSSQHNSGTERLA
EVIEKLAVPDDEIIVNIQGDEPLIPPVIVSQVAQNLQKYQVNMATLAVKIEDVEELFNPNVVKVLTDKDGYVLYFSRAVI
PWDRDQFVQLGKADLSQLQLHQHYFRHIGIYAYRAGFIKQYVQWQPTTLEQIERLEQLRVLWNGERIHVELAKQAPAVGV
DTVEDLEKVRSILSHV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-37 44
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 2e-38 44
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 3e-38 44