Gene Information

Name : CLD_0021 (CLD_0021)
Accession : YP_001780373.1
Strain : Clostridium botulinum Okra
Genome accession: NC_010516
Putative virulence/resistance : Resistance
Product : chloramphenicol O-acetyltransferase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG4845
EC number : 2.3.1.28
Position : 863445 - 864068 bp
Length : 624 bp
Strand : +
Note : identified by match to protein family HMM PF00302

DNA sequence :
ATGAATTTTAGAATTATTAACAAAAAAGATTGGGATAGAAAAGAATATTTTGAACATTATTTTTCTGAAGTTTCATGCAC
ATATAGTATGACTGTTAAATTGGATATTACAAAAATTAAAAATTCAAATCAAAAGCTATATCCAACAATATTATATTTTA
TTACAAAAGTAGTCAATAAACATAATGAATTTAGAACATCTTTTAACATGAATGGACAACTAGGTGTTTTTGAAGAAATG
ATTCCATGCTATACAGTATTTCATAAAGACACAGAAACCTTTTCTAATATCTGGACAGAGTACTCTGAGAATTATGATAT
TTTCTGCAAGTCATATGAAAAAGATATGCAGATGTTTAGTTCAGTAAAAGGATTGATAGCAAAACCAGATATACCTGCTA
ATAATTTTCCAGTGTCAATGGTACCATGGACATCATTTGATGGATTTAATCTAAACTTACAAAAAGGATATGAATATTTA
TTACCAATTTTCACTATTGGAAAATATTATAAAGAAAATGGTAGATACCTTTTACCATTAGCAATACAGGTTCATCATGC
TGTATGTGATGGATTTCATGTGTGTCGCTTTGTAAATGAATTACAGGAATTGATAAAAGGATAA

Protein sequence :
MNFRIINKKDWDRKEYFEHYFSEVSCTYSMTVKLDITKIKNSNQKLYPTILYFITKVVNKHNEFRTSFNMNGQLGVFEEM
IPCYTVFHKDTETFSNIWTEYSENYDIFCKSYEKDMQMFSSVKGLIAKPDIPANNFPVSMVPWTSFDGFNLNLQKGYEYL
LPIFTIGKYYKENGRYLLPLAIQVHHAVCDGFHVCRFVNELQELIKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cat AAL08441.1 chloramphenicol acetyltransferase Not tested SRL Protein 2e-39 42
cat CAJ77070.1 Chloramphenicol acetyltransferase Not tested AbaR1 Protein 4e-40 42
cat YP_006098370.1 chloramphenicol acetyltransferase Not tested Tn2411 Protein 5e-40 42
catA2 ACF06176.1 chloramphenicol acetyltransferase II Not tested Tn5036-like Protein 4e-39 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CLD_0021 YP_001780373.1 chloramphenicol O-acetyltransferase CP001581.1.gene2168. Protein 3e-52 51
CLD_0021 YP_001780373.1 chloramphenicol O-acetyltransferase NC_010111.5787932.p0 Protein 6e-46 47
CLD_0021 YP_001780373.1 chloramphenicol O-acetyltransferase CP004022.1.gene799.p Protein 7e-40 44
CLD_0021 YP_001780373.1 chloramphenicol O-acetyltransferase NC_010426.6155849.p0 Protein 4e-37 42
CLD_0021 YP_001780373.1 chloramphenicol O-acetyltransferase NC_010427.6155852.p0 Protein 4e-37 42
CLD_0021 YP_001780373.1 chloramphenicol O-acetyltransferase NC_010410.6002590.p0 Protein 2e-40 42
CLD_0021 YP_001780373.1 chloramphenicol O-acetyltransferase NC_011586.7045194.p0 Protein 2e-40 42
CLD_0021 YP_001780373.1 chloramphenicol O-acetyltransferase NC_010558.1.6276004. Protein 2e-40 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CLD_0021 YP_001780373.1 chloramphenicol O-acetyltransferase VFG1032 Protein 8e-40 42