Gene Information

Name : thiC (CLD_1631)
Accession : YP_001782548.1
Strain : Clostridium botulinum Okra
Genome accession: NC_010516
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 3159598 - 3160911 bp
Length : 1314 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAATTATACAACTCAAATGGATGCTGCTAAAAAAGGAATAGTTACAAAAGAGATGGAAATAGTAGCTAAAAAGGAAAA
TATGAATGTGAAAGACCTTATGAAATTGGTATCTAAAGGTAAGGTTGCTATACCTGCTAATAAAAATCATAAATCTTTAG
ATCCAGAAGGAATAGGACAAGGTTTAAGAACTAAAATAAATGTCAATTTAGGAATATCTAAAGATTGCTATAACATAGAT
ATGGAATTAGAAAAAGTACAAAAAGCAATAGATATGAAGGCAGAGGCTATAATGGATTTGAGCTGCTTTGGAAAAACAGA
AGAATTTAGAAAAAGATTGATAGACATGTCACCAGCCATAATAGGTACTGTTCCTATATATGATGCAGTAGGTTTCTATG
ATAAAGAATTAAAAGATATTACATCAGAAGAATTTTTAAAGGTAGCAGAGAAGCATGCAGAGAATGGAGCAGACTTTTTA
ACAATACATGTAGGTATGAATAGAAAAACTGCAGCTACATTTAAGAAAAATCCAAGAAGAATGAACATAGTTTCAAGAGG
AGGATCCCTTTTATATGCATGGATGGAACTAAATAATAAAGAAAATCCATTCTATGAAGGATTTGATAAACTTTTAGATA
TATGTGAAAAGTATGATGTTACATTAAGCTTAGGGGATGCTTGTCGTCCAGGCTGTATAGAGGATTCTACAGATGCAAGC
CAGATAGAAGAGCTTATAGCCTTAGGAGAACTTACCAAAAGAGCCTGGGAGAGGAATGTACAAGTTATAATAGAGGGACC
AGGACACATGACTTTAGATGAAATAGAAACAAATATGAAAATAGAGAAAAAATTATGTCATGGAGCTCCGTTCTATGTTT
TAGGACCAATAGTTACAGATATAGCTCCAGGTTATGATCACATAACTTCAGCTATAGGTGGTGCTATTGCAGCAACTCAT
GGTGCAGATTTCTTATGCTATGTAACCCCAGCAGAGCATTTAAGATTACCAAACTTAGATGATATGAAGGAAGGTATAAT
AGCGACAAAGATAGCAGCTCATGCAGCAGATCTAGCTAAAGGAGTAAAGGGAGCAAGAGATTGGGATAATGCTATGGCTA
AAGCTAGAAGAGATTTAGACTGGGAAAGAATGTTTGAGTTATCTATAGATGAAGAAAAAGCTAGAAGATATAGAGAAGAA
TCTAAGGCAAAAAGTAAAGATTCTTGTACAATGTGCGGAAAAATGTGTGCAGTAAGAAATATGAACAGAGTTACAGAAGG
AAAAGACTTAAACATGTTAAGAGATGATGATTAA

Protein sequence :
MNYTTQMDAAKKGIVTKEMEIVAKKENMNVKDLMKLVSKGKVAIPANKNHKSLDPEGIGQGLRTKINVNLGISKDCYNID
MELEKVQKAIDMKAEAIMDLSCFGKTEEFRKRLIDMSPAIIGTVPIYDAVGFYDKELKDITSEEFLKVAEKHAENGADFL
TIHVGMNRKTAATFKKNPRRMNIVSRGGSLLYAWMELNNKENPFYEGFDKLLDICEKYDVTLSLGDACRPGCIEDSTDAS
QIEELIALGELTKRAWERNVQVIIEGPGHMTLDEIETNMKIEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAIAATH
GADFLCYVTPAEHLRLPNLDDMKEGIIATKIAAHAADLAKGVKGARDWDNAMAKARRDLDWERMFELSIDEEKARRYREE
SKAKSKDSCTMCGKMCAVRNMNRVTEGKDLNMLRDDD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 2e-68 45
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 2e-68 45
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 2e-66 43