Gene Information

Name : Bcenmc03_3862 (Bcenmc03_3862)
Accession : YP_001777503.1
Strain :
Genome accession: NC_010515
Putative virulence/resistance : Resistance
Product : Bcr/CflA subfamily drug resistance transporter
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2814
EC number : -
Position : 784067 - 785266 bp
Length : 1200 bp
Strand : -
Note : TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: bur:Bcep18194_B2449 drug resistance transporter Bcr/CflA subfamily

DNA sequence :
ATGCCTGATCAAACCCGAACCACGCCCGCATGGGCTTACTCGTTGCCGTCGGCCCTGCTGCTGATGGCCCCTTTCGATCT
CCTCGCGTCGCTGGCGATGGACGTGTATCTGCCGGTGGTTCCGGAGATGCCGTCGGCGCTGCACACGTCGCCCGCCATGG
TGCAACTGACGCTGAGCGTCTACATGGTCGTCCTCGGCCTGGGCCAGTTGATGTTCGGCCCGCTGTCGGACCGGCTCGGA
CGTCGACCCGTGCTCCTGGGCGGTGCGCTACTGTTCTCGGTGGCTTCGCTGGCGCTTGCAATGGCGGGCAGCGGCGGCGT
GTTCGTCGCATTGCGCCTGCTGCAGGCGTTGGGCGCGTCGGCAGCGCTGGTGGCGACCTTTGCAACGGTGCGCGACGTGT
ATGCCGACCGTCCGGAAGGCAGCACCCTCTACAGCCAGTTCGGGGCGATCCTCGCGTTCGTCCCGGCGCTCGGGCCGATG
CTCGGCGCAGGCATTGCGCACGGTTTCGGATGGCGCGCGATCTTCATGACCCTCGGCGGCGCCGGATGTCTGGCGTTTTA
CCGCGCGTTGTCGCGTTGGCACGAAACCCGGCAGCAGGCCGGCGGCAAGCCGCGGCAATCCGCCGTATCGATCCTGCGCA
GTCCTTCTTTCCTCGTCTATTCGCTCGGTTTCGGCACGTCCATGGGCGCTTTTTTCGTGTTCTTTTCGATTGCGCCGCGT
GTGCTGGTCGGACAGGCCGGCTATTCCCGCACCGAATTCAGCGTGGCGTTTGCCACCGTCGCGATCGTGATGATCGGTGC
CGCGCGCTTTGCGCGATGGTTCGTGTCGAACTGGGGGATTCCGGGCTGTTTCGTGCGCGGCGCGGGCGTCATGATGGCCG
GCGCAATCGCGCTGGCGGCATGCACGGCCCTGATGGCGCCGTCATTCGTCTCGTTCGTGATGCCGATGTGGATCGTCGCG
ATCGGCATCGTGCTGATGTCGTCGGTGACGGCGAACGGCGCGCTTCGGGATTTCGACGACGCGGCGGGGACGGCGGTCGC
GTTGTATTACTGCGTGCAGAGCCTGATCGTCGGCGGGGCCGGCACGTTCGTGACGCTAGTGCTGCCCGGCGATACGCCGT
GGCCGCTGGCGGCGTTTTGTTTCGTCACGCCGACGGCATGCGTCCTCGCGCTCGCCGCATTGAAGCGTACGCGCGGATGA

Protein sequence :
MPDQTRTTPAWAYSLPSALLLMAPFDLLASLAMDVYLPVVPEMPSALHTSPAMVQLTLSVYMVVLGLGQLMFGPLSDRLG
RRPVLLGGALLFSVASLALAMAGSGGVFVALRLLQALGASAALVATFATVRDVYADRPEGSTLYSQFGAILAFVPALGPM
LGAGIAHGFGWRAIFMTLGGAGCLAFYRALSRWHETRQQAGGKPRQSAVSILRSPSFLVYSLGFGTSMGAFFVFFSIAPR
VLVGQAGYSRTEFSVAFATVAIVMIGAARFARWFVSNWGIPGCFVRGAGVMMAGAIALAACTALMAPSFVSFVMPMWIVA
IGIVLMSSVTANGALRDFDDAAGTAVALYYCVQSLIVGGAGTFVTLVLPGDTPWPLAAFCFVTPTACVLALAALKRTRG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
floR YP_005176183.1 florfenicol / chloramphenicol efflux protein Not tested ICEPmu1 Protein 2e-93 61
flo AAK02049.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 4e-95 60
floRc AGK06972.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 4e-95 60
floRc AGK07102.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 4e-95 60
cmlA9 ABZ01840.1 CmlA9 chloramphenicol efflux protein Not tested SGI2 Protein 2e-95 59
cmlA CAJ77032.1 chloramphenicol and florfenicol resistance protein Not tested AbaR1 Protein 2e-95 59
cml(A)5 ACY75522.1 CmLA(5) Not tested Tn6060 Protein 4e-70 49
cmlA5 CAJ77046.1 Chloramphenicol resistance protein Not tested AbaR1 Protein 6e-70 49

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Bcenmc03_3862 YP_001777503.1 Bcr/CflA subfamily drug resistance transporter DQ984668.gene.p01 Protein 2e-70 49
Bcenmc03_3862 YP_001777503.1 Bcr/CflA subfamily drug resistance transporter DQ522237.1.gene4.p01 Protein 2e-70 49
Bcenmc03_3862 YP_001777503.1 Bcr/CflA subfamily drug resistance transporter NC_010410.6003586.p0 Protein 2e-70 49
Bcenmc03_3862 YP_001777503.1 Bcr/CflA subfamily drug resistance transporter AF294653.1.gene4.p01 Protein 3e-70 49
Bcenmc03_3862 YP_001777503.1 Bcr/CflA subfamily drug resistance transporter AF156486.gene.p01 Protein 1e-68 48