Gene Information

Name : Bcenmc03_4200 (Bcenmc03_4200)
Accession : YP_001777841.1
Strain :
Genome accession: NC_010515
Putative virulence/resistance : Virulence
Product : type IV secretion/conjugal transfer ATPase
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG3451
EC number : -
Position : 1135251 - 1137731 bp
Length : 2481 bp
Strand : -
Note : TIGRFAM: type IV secretion/conjugal transfer ATPase, VirB4 family; PFAM: CagE TrbE VirB component of type IV transporter system; KEGG: bxe:Bxe_C0450 putative type IV secretion system protein VirB4/TraE

DNA sequence :
ATGAGCACACCGTCGGCACATGCAACCCTCGTACCGCGCGAAGTGGTGCTCGCAGATTTCATCCCATTTTCGTCGCACGT
CACGGACCGCGTGATTCGCACGCGCGAAGGTGACTATATACAAATCTGGAAGGTCCCCGGGATTGCTTTCGAGACGGCCG
ATCCTGCCGATATTCTCGCGCGTCATGTCACCTTCAATCAGTTGGTGCGCAATCTGCCGGGTGGCCACGTCGCGCTATGG
ACGCATCGGCTTCGGCGGCGTACCGCGGACAGGTTCGAGACGACCTATCTCAACCGATTCTGTCAGGATTTGGCTGAGCG
CTACTACGCGAGCTTTGCCGGTTACACGATGATGACCAACGAGCTTTACGTGAGCGCCGTATATCGCCCTCACCGGACGC
GATTGGGGCGGCTGTTTAGTCGTGCGGCACGCCGTACACCTGACGCTATTCAGCGCGATCAACAAGACGCATTGCGTGCG
TTGGCCGATATCGCTGCGCAGATCGAGACTGGTCTCAAACCGTGGTCGCCGTGTGCGCTCAGCGTGTATGAACGCGGCGA
TCCATTGACCAAGCGGCCCTGTCGCTATTCCGCCGCGCTTGAAATGCTTGGCTACCTGGTTAACGGAACGTGGGAGCCGG
TACCGGTTGGATACGGTCGAATTTGCGACACGTTACCAACCTCGCGCCTGTTCTTCCACCGTGAGAAGCTCGAGATCCGC
ACACCTACGCGTACCCGCTACGCGGCATTGCTCGACCTGAAGGACTATCCGGAGCAAACCGAGCCAGGCATGCTCAATGG
ATTGCTCTACGGCGACTTCGAGTACATCGAAACGCAAAGCTTTACCGTGCTCGACCGTCCCAGTGCCAAGGAGGCGCTCG
AGCGGCAGCGCAACCAACTGATTGCGGGAGATGACGTTGCTGTCTCGCAGATCGAGGCAATGGATCAGGCCGCGAACGAT
CTCGTCAATGGCGATTTCGTTTTGGGCGAGTACCACTACACGTTGGCCGTGCTGGGAGATACCTTGGATGAGGTAGTGCG
GCATGTCGCTCAAGCACGAACGAAGCTTGCAGACGCCGGCTTCCAGAGTGCGCTCATTGATCTGGTCGCCGATGCTGCGT
GGTTCGCGCAGTGCCCCGGCAACTGGCGATACCGACCGCGAGAGGCGAAGCTTACATCACGCAACTTTTGCGCGATGGCC
AGTTTGCACAACTTCGCGACTGGAAAGCGAGAGGGTAATCCGTGGGGCGAAGCTATCACGATTGTCAAAACGCCCAGCGG
GCAACCGCTCTATCTGAACTTTCACGCAACGCCCGAGAAAGTCGACTCAAACGACGAGAAGGCGCTTGCCAACACGCAGA
TCATCGGCCGAGCCGGTGCAGGCAAGACTGTGCTTGAACTGTTCCTGCTCGCGATGACAATGAAGTACGGTGTGATGGGC
GTGCTCTTCGACAAGGACCGAGGAGCGGAAATCGGGATTCGCGCCATGGGTGGTCAGTACACGGTATTTCACCGTGGTGA
GCCCACCGGCATGAACCCGTTCCAGTTGGAAGTGGACGAGGCGACACACAGTTTTTGGATACGTCTCGTGTGCAAGCTGG
TCGACAACGGAGTACCACTGTCCGCGAAGGATGAGCTCGATATCTCTCGCGCGATCCGGGAGGTCGCACGCATGGATCGA
TCGCTGCGTCGGTTGTCCATGGTCAGGCAACTCTTGCCAAACGTTGGAGATAACAGTCTTCATGCGCGGCTTGCCAAGTG
GTGCGCCGGCGGGCGCCTCGGCTGGGTGCTCGATAACCCCATTGACCGGATTGATCTAGATGCGCACCAATTGTTCGGCT
TTGACGATACAGAACTGCTCGACGATTCGGAGGTATGTGCGCCACTGACGATGGTGTTGCTGCATCTGACCGAACGCCTG
ATCGATGGGCGGCGTTTCATCTATGTGATGACCGAGTTCTGGAAGCGCCTGCGCGATCCGGTGTTCAGCGAGTTTGCCAA
CGACAAGCAAAAGACCATTCGCAAGCAAAATGGCCTGGGTATCTTTGACACCCAGTCGCCTGCGGACGTGTTGAGCAGTC
CGATCTCTCGTGCGCTTGTAGAGCAGACGGCTACATTCTTCTTCCTCCCCAACCCTAGCGCAGACCACGATGATTATGTC
CACGGTTTCAAGCTGACCGAAGCAGAATTCAACATTGTGAGACGCATGGGTGAGCACAGTCGGCTGTTCTTGGTCAAGCA
GGGTCATCGTTCAGCAGTCGGGCGACTCGATCTCTCGGGATTGGGCGACGTGCTCGATGTCCTGTCGGGCACGTCAGACA
ATGTTGCGTTGCTCAATACGATCCGGGCCAAGGTCGGGGACGACCCCGATGTGTGGTTGCCGCGCTTTCATGATGCCCTG
ACTGCTCGCCGGCGCCAAACGAGTGCGTTTCAAACCGCATTGTCGAGCACCGCTACACACGTGCAAGGTGGTGTTCTATG
A

Protein sequence :
MSTPSAHATLVPREVVLADFIPFSSHVTDRVIRTREGDYIQIWKVPGIAFETADPADILARHVTFNQLVRNLPGGHVALW
THRLRRRTADRFETTYLNRFCQDLAERYYASFAGYTMMTNELYVSAVYRPHRTRLGRLFSRAARRTPDAIQRDQQDALRA
LADIAAQIETGLKPWSPCALSVYERGDPLTKRPCRYSAALEMLGYLVNGTWEPVPVGYGRICDTLPTSRLFFHREKLEIR
TPTRTRYAALLDLKDYPEQTEPGMLNGLLYGDFEYIETQSFTVLDRPSAKEALERQRNQLIAGDDVAVSQIEAMDQAAND
LVNGDFVLGEYHYTLAVLGDTLDEVVRHVAQARTKLADAGFQSALIDLVADAAWFAQCPGNWRYRPREAKLTSRNFCAMA
SLHNFATGKREGNPWGEAITIVKTPSGQPLYLNFHATPEKVDSNDEKALANTQIIGRAGAGKTVLELFLLAMTMKYGVMG
VLFDKDRGAEIGIRAMGGQYTVFHRGEPTGMNPFQLEVDEATHSFWIRLVCKLVDNGVPLSAKDELDISRAIREVARMDR
SLRRLSMVRQLLPNVGDNSLHARLAKWCAGGRLGWVLDNPIDRIDLDAHQLFGFDDTELLDDSEVCAPLTMVLLHLTERL
IDGRRFIYVMTEFWKRLRDPVFSEFANDKQKTIRKQNGLGIFDTQSPADVLSSPISRALVEQTATFFFLPNPSADHDDYV
HGFKLTEAEFNIVRRMGEHSRLFLVKQGHRSAVGRLDLSGLGDVLDVLSGTSDNVALLNTIRAKVGDDPDVWLPRFHDAL
TARRRQTSAFQTALSSTATHVQGGVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
trwK YP_001610476.1 TrwK protein Virulence Not named Protein 2e-161 44
trwK CAD42844.1 TrwK protein Not tested trw-PAI Protein 1e-161 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Bcenmc03_4200 YP_001777841.1 type IV secretion/conjugal transfer ATPase VFG2211 Protein 8e-175 48
Bcenmc03_4200 YP_001777841.1 type IV secretion/conjugal transfer ATPase VFG2259 Protein 1e-161 43
Bcenmc03_4200 YP_001777841.1 type IV secretion/conjugal transfer ATPase VFG0018 Protein 3e-147 42