Gene Information

Name : Xfasm12_2283 (Xfasm12_2283)
Accession : YP_001776760.1
Strain : Xylella fastidiosa M12
Genome accession: NC_010513
Putative virulence/resistance : Unknown
Product : Type I site-specific deoxyribonuclease
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : 3.1.21.3
Position : 2427594 - 2430728 bp
Length : 3135 bp
Strand : -
Note : KEGG: xfa:XF2739 type I restriction-modification system endonuclease

DNA sequence :
ATGGCATTTTTATCAGAAGCCACCTTGGAACAAGCCGTGCTGGATCAGCTACGCCTATTGGGCTACAGCATCGAGCGTGA
AGAAAACATCGGCCCTGATGGCTATCGTCCGGAACGCGCCAGTTATGACCAGGTTGTACTCAAACAACGCTTCGTTGATG
CCGTTACACGTCTCAACCCAGGGCTGCCGCCAGAGGCCAGACAGGATGCAATCCGTAAGGTCACACAGTCTGAGTTGCCA
TCATTACTCGAAGAAAACCGCCGCATCCACAGACTGATCACCGAAGGTGTCGATGTCGAATACTATGCCCAGGACGGTAC
CCTGACAGCGGGCAACGTTGCACTCATCGACTTCGACCACCCCCAACAGAACGATTGGTTGGCCGTGAACCAGTTCGTGG
TTATTGCTGATCACTACAACCGGCGTCCTGACGTGGTCCTCTTCTTGAACGGCTTGCCATTGGCCGTGATCGAATTGAAG
GCACCAGGAAGTATCAATGCAACCTTGATTGCAGCCTTCAATCAGTTGCAGACCTATAAAGAGCAGATCCCGGCACTGTT
CAACACCAATGCCCTGCTAGTGACTTCTGACGGGATGACGGCCCGCTTCGGCTCGCTGTCGGCCGACTTAGAACGCTTCA
TGCCTTGGCGCACCACCGACGGCACCGACATTGCTCCAAAGGGGGTGCCGGAACTTGCAACACTGATTGAGGGGATATTC
GAGCCGCATCGCCTGCTCGACCTACTGCGCCATTTCACCGTTTTCCGGAAGACGGATGCTGGCTTGGCGAAGATCATCGC
CGGTTACCACCAATTCCACGCTGTACGGCAGGCCATCAATAGCACCGTGGCTGCTTCCTCGCCCCAGGGGAATCAACAGA
TTGGTGTCATCTGGCACACCCAAGGTTCCGGAAAAAGCCTACTGATGGCTTTCTATGCTGGACAACTGGTCAAACACCCC
GCAATGGCCAACCCAACGCTTGTTGTACTCACAGATCGTAACGATCTTGACGATCAGTTATTCACCACATTCTCACAGTG
CGGTGATTTAATCCGGCAAACCCCGGTACAGGCCCAGAGCCGCGACCAGGTGCGGAAACTCTTGAACCGTGCATCCGGCG
GAGTGATTTTTACCACCTTGCAGAAATTCGGTGACATCACAGAACCACTGACCACACGACGTAACGTCGTCGTCATCGCT
GATGAAGCACACCGCAGCCAATATGGCTTCAAAGCCAAAGTGGACAACAAAACCGGCAAAATCTCCTATGGCTTCGCTAA
GTACATGCGTGATGCCCTGCCCAACGCATCTTGCATCGGTTTTACCGGCACACCGATTGAGGCCGACGACGTCAATACCC
CAGCCGTATTCGGCAACTACATCGACATCTACGACATCAGCCGTGCGGTCGAAGATGGTGCGACCGTGCCGATCTACTAC
GAATCGCGGCTGGCACGTATTGCACTGGATGAAGCCGAGAAACCGCAGATTGATGCTGAAGTCAACGCACTGACCGAAGC
CGATTCCGAGGCCGAGCAAGAGCGCTTCAAGAAAAAATGGTCAACGGTCGAAACCTTAGTCGGCAGTGATAAACGGCTTG
CTTTAATCGCCAAGGACATCATCACCCATTGTGAAGATCGCCTAGCCGCTCTGGATGGGAAGGCGATGGTGGTCTGTATG
AGCCGTCGTATCTGTGTCGCCCTATACGATCACATCGTGACACTGCGGCCCGATTGGCACAGCACCGATAACAAGGCCGG
ATCGCTCAAAATCGTCATGACCGGCACGGCCAGTGATCCGCAGCAGTGGCGACAGCATATCGGCAACAAAGCCCGGCGTG
ATCTGCTGGCCGAACGTGCCCGTGACCCCAAAGACCCACTCAAACTAGTGATTGTCCGGGATATGTGGCTCACTGGTTTT
GACGCCCCCTGCATGCACACCATGTACCTTGACAAGCCGATGCAAGGGCATGGATTGATGCAGGCCATTGCACGGGTGAA
CCGCGTGTTCCGCGACAAACCCGCCGGATTGATCGTGGACTACATCGGCATCGCACAAAATCTCAGAACGGCCCTGCAAC
AGTATTCGAAGAACGATCAGCAACACACCGGTGTTGATGAAGCACAGGCCATTGCAGTCATGATGGAGAAATACCAGATC
GTCCGGGATATGTACCACGGCTACGATTACCTCACCGCAATGAGTGGTACCCCACAAGAGCGCCTTGCCATGATGGGGGG
AGCCATTGAGTGGATACTCAATCTTCAGCAGCAACTGGCAGCCACAGCACAGACCAAAGAAGGCAAAAAAGAGGCCCACC
GCCGCTATCAAGATGCTGTGTTAGCGTTGTCTAAGGCGTTCGCCCTGGCATCGGCCTCCGATGAGGCCCGCCACATCCGT
GAAGAAGTCGGCTTCTTCCAGGCGATCCGTGCCGCCCTCGTCAAGAGCGCCGATCATTCCGGGGGTAGCGAACCGCAACG
CGACCTGGCCATCCAGCAGATCGTGAGCCGAGCCGTCGTCTCGACGGAGATCGTCGATATCCTGGCTGCTTCTGGAATCA
ACAGCCCAGATATTTCCATCCTGTCCGACGCATTTCTGGCTGAAATTCAGCAGATGCAACGAAAACACCTCGCCTTGGAA
GCCTTGCGCAAGCTGTTGAACGACCGCATTCGTTCCCGCAGCACCGCTAACCTCGTGCAGACCAAGGCCTTCTCCGAGCG
CCTGGAAGGTGCTGTGGCGCGCTACCACGCCAACGCGATCACCACTGCCCAGGTGCTCCAGGAACTGATCCAATTGGCCA
AAGACATCCGTGCTGCTCGCCAGCGCGGCGAAGCCACCGGATTGTCTGATGAAGAGGTTGCCTTCTACGACGCACTGGCC
GAAAACGAAAGCGCTGTACAGATGATGGGAGATCACACACTCCGGCTGATCGCTCACGAATTACTCATGCGCCTGCGCGA
AAACGTCTCAGTGGATTGGGCCCATCGTGACTCCGCCCGTGCCCGGATGCGTGTCCTAGTGAAGCGCATCCTGCGCAAGT
ACGGCTACCCGCCTGATCTACAGAACACGGCTGTGCAGACCGTCCTCCAGCAGGCCGAAGCCTTCTCGTCCCAGTGGAGT
GATTCTGGACCCTAA

Protein sequence :
MAFLSEATLEQAVLDQLRLLGYSIEREENIGPDGYRPERASYDQVVLKQRFVDAVTRLNPGLPPEARQDAIRKVTQSELP
SLLEENRRIHRLITEGVDVEYYAQDGTLTAGNVALIDFDHPQQNDWLAVNQFVVIADHYNRRPDVVLFLNGLPLAVIELK
APGSINATLIAAFNQLQTYKEQIPALFNTNALLVTSDGMTARFGSLSADLERFMPWRTTDGTDIAPKGVPELATLIEGIF
EPHRLLDLLRHFTVFRKTDAGLAKIIAGYHQFHAVRQAINSTVAASSPQGNQQIGVIWHTQGSGKSLLMAFYAGQLVKHP
AMANPTLVVLTDRNDLDDQLFTTFSQCGDLIRQTPVQAQSRDQVRKLLNRASGGVIFTTLQKFGDITEPLTTRRNVVVIA
DEAHRSQYGFKAKVDNKTGKISYGFAKYMRDALPNASCIGFTGTPIEADDVNTPAVFGNYIDIYDISRAVEDGATVPIYY
ESRLARIALDEAEKPQIDAEVNALTEADSEAEQERFKKKWSTVETLVGSDKRLALIAKDIITHCEDRLAALDGKAMVVCM
SRRICVALYDHIVTLRPDWHSTDNKAGSLKIVMTGTASDPQQWRQHIGNKARRDLLAERARDPKDPLKLVIVRDMWLTGF
DAPCMHTMYLDKPMQGHGLMQAIARVNRVFRDKPAGLIVDYIGIAQNLRTALQQYSKNDQQHTGVDEAQAIAVMMEKYQI
VRDMYHGYDYLTAMSGTPQERLAMMGGAIEWILNLQQQLAATAQTKEGKKEAHRRYQDAVLALSKAFALASASDEARHIR
EEVGFFQAIRAALVKSADHSGGSEPQRDLAIQQIVSRAVVSTEIVDILAASGINSPDISILSDAFLAEIQQMQRKHLALE
ALRKLLNDRIRSRSTANLVQTKAFSERLEGAVARYHANAITTAQVLQELIQLAKDIRAARQRGEATGLSDEEVAFYDALA
ENESAVQMMGDHTLRLIAHELLMRLRENVSVDWAHRDSARARMRVLVKRILRKYGYPPDLQNTAVQTVLQQAEAFSSQWS
DSGP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 48
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 47
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 47
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 47