Gene Information

Name : Xfasm12_2269 (Xfasm12_2269)
Accession : YP_001776748.1
Strain : Xylella fastidiosa M12
Genome accession: NC_010513
Putative virulence/resistance : Virulence
Product : type I restriction-modification system DNA methylase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 2408366 - 2410657 bp
Length : 2292 bp
Strand : -
Note : KEGG: xft:PD2072 type I restriction-modification system DNA methylase

DNA sequence :
GTGCGCGGCAAGTACCGCGACGTGATCCTGCCTTTCACCGTGCTGCGACGGCTCGACGCCGTGCTGGAAGCCACCAAGGA
CGCGGTGCTGGAACGCAAAAAGTTCCTCGACGCCCACAACGTGGCCGAGCAGGACGGCGCGCTGCGCATGGCGGCGGGTC
AGGCGTTCTACAACGTCTCGGAATTCACGTTGGCCAAGCTCAAGGCCAGCGCGGCAGGGCAGCGCCTGCGTGATGACTTC
ATTGCGTATCTGGACGGCTTCTCGCGCGACGTGCAGGAGATCCTCACCAAGTTCAACTTCCGCAACCAGATCCAGAAGCT
GGTGGATTCCCATGTTCTCGGCTACCTGATCGAAGACTTCCTCAACCCTGAGGTCAATCTTGCGCCGCTGCCGGTGAAGG
ATGCCGACGGCCGCATCAAGTTGCCCGCGCTGGACAACCACGGCATGGGTACGGTGTTCGAGGAGCTGATCCGTCGTTTC
AACGAAGACAACAACGAAGAGGCGGGCGAGCACTTCACCCCGCGCGACGTGGTGCAGCTCATGGCCAAGCTGTTGTTTCT
GCCGGTGGCCGAGCGCATTGAGTCCAGCACCTATTCGCTCTACGACGGCAGTTGCGGCACCGGCGGCATGCTGACCGTGG
CTGAGGAAGCCCTGCACGCGCTGGCCGAGCAGCACGGCAAGGAGGTCTCCATTCACCTGTTTGGCCAGGAGATCAGCGAC
GAAACCTACGCCATCTGCAAAGCTGACCTACTTTTGAAGGGCGAAGGTGCGGAAGCCCAGAACATCGTCGGCGGCGCGGA
TAAATCCACCCTGTCCGCCGACCAGTTCCATTCGCGCGCATTCGATTTCATGATTTCCAACCCGCCCTACGGCAAGAGTT
GGAAAACCGATCTGGAGCGCATGGGCGGCAAGAAGGGGTTCAGTGACCCCCGCTTTATCGTCAGCCACGGTGGCGATTCC
GAGTTTAAGCTCCTCACCCGTTCCAGCGACGGGCAGCTCATGTTCCAGGTGAACAAACTGCAAAAGATGAAGCACAACAC
GCCACTGGGCAGCCGTATCGCGCTGGTGCATAACGGTTCGGCACTGTTCACCGGCGACGCGGGCCAGGGCGAGAGCAACA
TCCGCCGCTGGGTGCTGGAGAACGATTGGCTCGAAGCCATCATCGCCCTGCCGCTCAACATCTTCTACAACACCGGCATT
GCCACCTACATCTGGGTGCTGGCCAATAAGAAGGCCGAAGCGCGCCGTGGCAAGGTGCAGTTGATCGACGCATCGCAGTG
GTTCCAGCCGCTGCGCCGCAACCTCGGCAAGAAGAACTGCGAACTGGGTGCTGCCGATATTGCGCGCATCCTCGATCTCT
ACCTCGGCCAGGCGCAGGAAGCTGCGCAGTCCAAATGGTTCGACACGCAAGACTTTGGTTATTGGAAGATCACCATTGAG
CGCCCGTTACGCCTGAAAAGCCAGCTCTCTGACGAACGCATTGAGTCACTGCGTTTTGCCACTGGCGACGAGGCATTGCG
CGCTGAGATCTACGCTACCCACGGCGAGGCGCTGTATACCGAGTTCGCCAAGCGCAAACCGGCCATTGAGGCATGGCTGA
AAGGCGAGGACGAGAACGAAGACGACGACAACGAAGATAGCGACAGCGGCGACGACAACGAGGCCCCCGCCGCCCGCAAA
GCTGTGCCCGTTAAGCGCCGCAAAAAGCTGCTTGATGCATCGACGTGGCAGCGCGACAAAGCGCTGATGGAGGTGGCGCA
ACGGGCGCAGCAGACATTGGGCCACGCCGTGTTCGACGACCACAATGCGTTCTGCGCCTGCTTTGATGCAGTGTGCAAGG
CGCAGGACGCACGCTTAAGCGCGCCGGAGAAGAAGGTCATCTACAAGGCGGTGAGCTGGCGCGATGACGCCGCACTGCCG
GTCATCGCCAAGCGCAGTAAGCTCAAGGCGGGTGACTACTTCGAGCCCGGCTTTGATGGTGCGTATCTGGAAACCGTGGG
CAAGGATCGCTTCATGGTCGAGTACGAACCAGACAGCGCGCTGCGCGATACCGAGCAGGTGCCGTTGAAGGAACCGGGCG
GCATTGATGCCTTTTTTTCCCGCGAAGTGCTGCCGCACGCGCCGGACGCCTGGATCGCTACGAACAAGACTCAGGTTGGC
TACGAGATTTCTTTCTCTCGCTATTTCTACAAGCCCGTGCCGTTGCGGACGCTGGCCGAAATCCGTGCCGATATCCTCGT
GCTGGAGCAGCAGACGGAAGGGTTGCTGCATAAGATTGTGGGGGGGGCGTGA

Protein sequence :
MRGKYRDVILPFTVLRRLDAVLEATKDAVLERKKFLDAHNVAEQDGALRMAAGQAFYNVSEFTLAKLKASAAGQRLRDDF
IAYLDGFSRDVQEILTKFNFRNQIQKLVDSHVLGYLIEDFLNPEVNLAPLPVKDADGRIKLPALDNHGMGTVFEELIRRF
NEDNNEEAGEHFTPRDVVQLMAKLLFLPVAERIESSTYSLYDGSCGTGGMLTVAEEALHALAEQHGKEVSIHLFGQEISD
ETYAICKADLLLKGEGAEAQNIVGGADKSTLSADQFHSRAFDFMISNPPYGKSWKTDLERMGGKKGFSDPRFIVSHGGDS
EFKLLTRSSDGQLMFQVNKLQKMKHNTPLGSRIALVHNGSALFTGDAGQGESNIRRWVLENDWLEAIIALPLNIFYNTGI
ATYIWVLANKKAEARRGKVQLIDASQWFQPLRRNLGKKNCELGAADIARILDLYLGQAQEAAQSKWFDTQDFGYWKITIE
RPLRLKSQLSDERIESLRFATGDEALRAEIYATHGEALYTEFAKRKPAIEAWLKGEDENEDDDNEDSDSGDDNEAPAARK
AVPVKRRKKLLDASTWQRDKALMEVAQRAQQTLGHAVFDDHNAFCACFDAVCKAQDARLSAPEKKVIYKAVSWRDDAALP
VIAKRSKLKAGDYFEPGFDGAYLETVGKDRFMVEYEPDSALRDTEQVPLKEPGGIDAFFSREVLPHAPDAWIATNKTQVG
YEISFSRYFYKPVPLRTLAEIRADILVLEQQTEGLLHKIVGGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC1769 NP_231404.1 DNA methylase HsdM Not tested VPI-2 Protein 3e-140 44
VC0395_A1367 YP_001217310.1 DNA methylase HsdM Not tested VPI-2 Protein 3e-140 44
VPI2_0017c ACA01834.1 DNA methylase HsdM Not tested VPI-2 Protein 7e-140 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Xfasm12_2269 YP_001776748.1 type I restriction-modification system DNA methylase VFG1102 Protein 1e-140 44