Gene Information

Name : alr (Xfasm12_1999)
Accession : YP_001776499.1
Strain : Xylella fastidiosa M12
Genome accession: NC_010513
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 2082281 - 2083390 bp
Length : 1110 bp
Strand : -
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
TTGCCCGCAAGAGTGTGCTCCGTGCGTCCCGCCCACGCCGTAATTGATCTGGATGCGTTACGTCACAATTATCGATTTGC
TCGCCGTCTTGGCGGTGGCAAGGCGTTAGCTGTGGTGAAAGCCGATGCGTATGGTCACGGTGCGGTGCGTTGTGCGCAGG
CTTTGGAGGCTGAAGTTGATGGTTTTGCGGTGGCGTGTATCGAAGAGGCGTTGGAGTTACGCCAAGCCGGTATCCAGGCA
CCGATCCTGTTGCTGGAAGGATTTTTCGAGGTTGAAGAGCTGGAATTGATTGCTAAGCACAATTTATGGACTGTGATTGC
TTCGTCCTGGCAGGTGCGGGCGTTGGCTGCGTTCCACAGTCCATCTCCAATTGGGGTGTGGCTTAAGTTGGATAGTGGCA
TGCATCGGCTTGGTTTGGAGCCAAAGGAGTTTCGTGATGCTTGGATGTCTCTGCATAGTCTGCCGCAGGTGGGCGAGGTC
GTCTTGATGACGCATTTGGCCCGTGCTGATGAGTTGGATAATCCTCGTACCAATGAGCAGGCATCGGTTTTTGCACATGC
TTCGCAGGGAATGGTGGCGCCAGCAAGTGTGTGTAACTCTTCAGGTTTGCTTGGTTGGGCAGGGTTGTACAGTGATTGGG
GTCGGCCCGGGTTAATGTTGTACGGTGTCAATCCTATTTCGCAGGAGAGCACGTCACTCAGTGGGCCATTGCGTCCTGTG
ATGATGGTGTATTCGAAGCTGATCGCGGTACGCGAGTTGCCTGCCGGCGAGCCGGTTGGCTATGGGGCATCCTTTGTCAC
TGAGCGGCCAACCCGGGTTGGTGTGGTAGCGATGGGCTATGCAGACGGTTACCCGTATTTTGCGGTCAATGGTACGCCGC
TCTTGGTTGATGGGCGTGTTTGTCCGTTGATCGGCCGGGTTTCTATGGACATGTTGACGGTTGATCTGACAGACCATCCG
CAGGCGGATGTTGGCAGTCAAGTGCAATTGTGGGGTGTGCAACCGGGTGTGGCTGAACTTGCGGCACATTGTAATTTGAG
CGCTTATCAGTTGTTGTGCGGTCTTAAGCGTGTCCGTCGATACTATTTGGGTGAGATGGGCGCAGTGTGA

Protein sequence :
MPARVCSVRPAHAVIDLDALRHNYRFARRLGGGKALAVVKADAYGHGAVRCAQALEAEVDGFAVACIEEALELRQAGIQA
PILLLEGFFEVEELELIAKHNLWTVIASSWQVRALAAFHSPSPIGVWLKLDSGMHRLGLEPKEFRDAWMSLHSLPQVGEV
VLMTHLARADELDNPRTNEQASVFAHASQGMVAPASVCNSSGLLGWAGLYSDWGRPGLMLYGVNPISQESTSLSGPLRPV
MMVYSKLIAVRELPAGEPVGYGASFVTERPTRVGVVAMGYADGYPYFAVNGTPLLVDGRVCPLIGRVSMDMLTVDLTDHP
QADVGSQVQLWGVQPGVAELAAHCNLSAYQLLCGLKRVRRYYLGEMGAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 9e-53 42