Gene Information

Name : Xfasm12_1985 (Xfasm12_1985)
Accession : YP_001776485.1
Strain : Xylella fastidiosa M12
Genome accession: NC_010513
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 2071106 - 2072323 bp
Length : 1218 bp
Strand : -
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGAGCATTCATGATGTGCACGAAGGCACGTGTCACGTGACCACTTCCGCGGTGCGTGCTGGGATCGATTCCGACACTGC
TCATGGGGCAGTGACGCCACCGATTGTGCTTTCATCCAACTTCTCGTTTGAACGTTTCGGTCATAAGCGTAAGTACGATT
ACACACGTAGTGCTAATCCAACGCGGGATCTGCTCGGCGAGGCGCTTGCGGAGTTGGAGGGTGGTGCCGGTGGTGTGGTC
ACGGCGACTGGGATCGCTGCGATTACGTTGGTGTTGCACGCATTGCTCCGGCCGGGGGATCGTTTGGTTGTGCCACATGA
TGCTTACGGTGGCAGTTGGCGTTTGTTCAATGCGTTGGCTCAAAAGGGACATTTTGAATTGATCACGGTCGATTTGACGG
ATGCACGATCACTGGTTGAGGCATTGGCACTACCACCGAAGTTGGTATTGATCGAAACTCCTTCCAATCCATTGTTACGT
ATTACTGATTTGGGTGCGGTGATTGAGGCAGCGCACCGTGTCGGTGCTTTGACTGTGGTCGACAATACGTTTATGTCTCC
GGTGTTGCAGCGTCCTTTAGAGTTCGGCGCTGACTTGGTATTGCATTCGACAACGAAGTACATCAATGGCCACAGTGATG
TTGTCGGTGGCGTTGTTGTGGCACGTGATGTTGCGCACTATCAGCAGTTGGTGTGGTGGGCGAATGCGCTGGGTCTGACC
GGCTCGCCATTCGATGCGTTCTTGACGTTGCGGGGGGTGCGCACGCTGGATGCGCGTTTGCGTGTGCATCAGGAGAATGC
GCAGATGATTGCAGCGTTACTGGAGGGGCATGGTGTGGTGAAGCACGTGCATTACCCAGGGTTGGCTTCGCATCCGGGGC
ATGTGCTGGCGGGGCGGCAGCAAAAAGGGTTCGGTGCCATGCTCAGTTTCGAGTTGCAGGGTGGGGAAGAGGCGGTGCGG
GCTTTTGTCAGTGGCTTGCGTTATTTCACGCTGGCTGAGTCGCTGGGTGGGGTTGAGAGTTTGATCGCTCATCCGGCTTC
GATGACGCATGCTGCCATGACGCCCGAGGCGCGTGCTAAAGCGGGTATCTCTGATGGGTTGTTGCGCTTGTCGGTGGGGA
TTGAGGCCGGTGAGGATTTGATCGTTGATCTGGTGGCTGGTTTGCGGCGTGCTCAGGCGGTGTGTGATGGAGCGGCGCGG
GAAGAGTGCAACGTGTGA

Protein sequence :
MSIHDVHEGTCHVTTSAVRAGIDSDTAHGAVTPPIVLSSNFSFERFGHKRKYDYTRSANPTRDLLGEALAELEGGAGGVV
TATGIAAITLVLHALLRPGDRLVVPHDAYGGSWRLFNALAQKGHFELITVDLTDARSLVEALALPPKLVLIETPSNPLLR
ITDLGAVIEAAHRVGALTVVDNTFMSPVLQRPLEFGADLVLHSTTKYINGHSDVVGGVVVARDVAHYQQLVWWANALGLT
GSPFDAFLTLRGVRTLDARLRVHQENAQMIAALLEGHGVVKHVHYPGLASHPGHVLAGRQQKGFGAMLSFELQGGEEAVR
AFVSGLRYFTLAESLGGVESLIAHPASMTHAAMTPEARAKAGISDGLLRLSVGIEAGEDLIVDLVAGLRRAQAVCDGAAR
EECNV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 7e-44 43
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-48 42
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-49 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Xfasm12_1985 YP_001776485.1 cystathionine gamma-synthase BAC0207 Protein 8e-46 42