Gene Information

Name : guaA (Xfasm12_1588)
Accession : YP_001776127.1
Strain : Xylella fastidiosa M12
Genome accession: NC_010513
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1658868 - 1660436 bp
Length : 1569 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACGCCGAATATTCATCACGACAAAATTCTTATCCTCGATTTCGGCGCACAGTACACCCAGTTGATTGCCCGTCGTAT
CCGTGAAATTGGTGTCTACTGCGAAGTGTGGCCCTGGGATCACTCCCCTGAAGAGATTCTGAGCTTCGGAGCCAAAGGTA
TCATCCTCTCCGGTGGCCCTGAATCGACCACATCCCCGGGTGCGCCTGCAGCACCGCAGCACGTCTTTGATAGTGACTTA
CCAATCTTCGGTATTTGCTATGGCATGCAAACCATGGCCGTACATCTTGGGGGTGCGACCGAGGCAGCCGACAAACGTGA
GTTTGGTCATGCCTCGGTCCAGGTGATTTACCCGGATACCTTGTTTTCCGGCTTGTCCGATCATCCCTCTGAGTTCCGTC
TGGATGTGTGGATGAGTCATGGTGACCATGTTTCACGCGTCCCGCCCGGCTTCACCATTACAGCCGCCACTGACCGCATC
CCCATTGCGGCGATGAGTCGCGAGGATAAGCGCTGGTATGGCGTGCAATTCCATCCGGAAGTGACCCATACCTTACAGGG
ACAGGCTTTATTGCGCCGTTTTGTGGTTGATATATGTGGCTGCCAGACGTTATGGACTGCCGCTAACATTATTGAAGACC
AAATCGCTCGTGTGCGTGAACGTGTCGGTCGCGATGAAGTCATTCTCGGCCTGTCTGGTGGCGTTGATTCTTCCGTCGTC
GCCGCACTTTTACACAAAGCCATTGGTAGCCAACTGACGTGTGTATTTGTTGATACCGGCTTGCTTCGCTGGGGGGAAGG
CGACCAAGTGATGGCCATGTTTGAGGAACATATGGGCGTCAACGTGGTACGTATCAATGCGGCATCGCGTTACTTCGACG
CACTGCAAGGTGTCTACGACCCAGAAGCCAAACGCAAAATCATCGGCAACCTGTTCATCCAGATATTCGAGGAAGAGGCC
AGCAAACGAAAGCAGGCCAAATGGTTGGCCCAAGGCACGATTTATCCTGATGTGATCGAATCGGCCGGCAGCAAAACCGG
CAAAGCCCACGTAATCAAAAGCCATCACAACGTCGGCGGCTTGCCGGAGCAGATGACCCTGGGTATGGTCGAACCATTAC
GTGAATTGTTCAAAGATGAAGTGCGCCGCCTTGGCGTTGCACTGGGCTTGCCCCATGCCATGGTATATCGCCATCCATTC
CCAGGACCTGGCTTGGGAGTGCGTATCCTTGGTGAAGTCAAGCCGGAGTATGCCGAGTTACTGGCCAAGGCTGACTCGAT
TTTTATTGATGAACTCCATCAAGCCGACCTGTACGACAAGGTCAGCCAAGCCTTTGCAGTCTTTCTTCCGGTGAAATCAG
TTGGCGTTGTTGGTGATGCCCGTGCGTACGAATGGGTGATTGCACTGCGCGCGGTTGAGACCGTTGATTTCATGACGGCA
CACTGGGCACCACTGCCGTATGACTTCCTGAGTACCGTCTCCAACCGCATCATCAATGAACTACGCGGCGTGTCCCGTGT
TGTCTACGATATTTCCGGAAAACCGCCAGCCACGATTGAGTGGGAGTGA

Protein sequence :
MTPNIHHDKILILDFGAQYTQLIARRIREIGVYCEVWPWDHSPEEILSFGAKGIILSGGPESTTSPGAPAAPQHVFDSDL
PIFGICYGMQTMAVHLGGATEAADKREFGHASVQVIYPDTLFSGLSDHPSEFRLDVWMSHGDHVSRVPPGFTITAATDRI
PIAAMSREDKRWYGVQFHPEVTHTLQGQALLRRFVVDICGCQTLWTAANIIEDQIARVRERVGRDEVILGLSGGVDSSVV
AALLHKAIGSQLTCVFVDTGLLRWGEGDQVMAMFEEHMGVNVVRINAASRYFDALQGVYDPEAKRKIIGNLFIQIFEEEA
SKRKQAKWLAQGTIYPDVIESAGSKTGKAHVIKSHHNVGGLPEQMTLGMVEPLRELFKDEVRRLGVALGLPHAMVYRHPF
PGPGLGVRILGEVKPEYAELLAKADSIFIDELHQADLYDKVSQAFAVFLPVKSVGVVGDARAYEWVIALRAVETVDFMTA
HWAPLPYDFLSTVSNRIINELRGVSRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-124 50
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-124 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-124 50
guaA NP_938969.1 GMP synthase Not tested Not named Protein 7e-112 49