Gene Information

Name : thyA (Xfasm12_1504)
Accession : YP_001776049.1
Strain : Xylella fastidiosa M12
Genome accession: NC_010513
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 1570115 - 1570909 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
GTGAAGCAGTACCTTGAATTACTGAATGATGTGCTTGTGCATGGCATACAAAAGCCTGACCGCACTGGCACGGGGACACG
CAGTGTGTTCGGTTGGCAGATGCGATTTGACTTGAGCCAAGGTTTTCCACTCGTTACGACTAAAAAGCTGCATTTGCGTT
CGATCATTCACGAGTTGCTATGGTTTCTCAGGGGGGAAACCAATATTGCTTATCTTAAGAAGCATCAGGTACACATCTGG
GACGAGTGGGCCGATGCCACGGGTGAGTTGGGACCTGTTTACGGCAAGCAATGGCGCCGTTGGGCTGGCGCGGATGGTCA
CGAGATCGACCAAATCCGTTGGTTGGTGGAGGAGATCAAGCGTAATCCAGATTCGCGCCGCTTGGTGATTAGTGCTTGGA
ATGTGGCTGATCTTCCACAGATGGCTTTGGTGCCGTGCCATGCACTATTTCAATTCTATGTTGCCAATGGCAAATTGAGC
TGTCAGCTTTATCAACGTAGCGCTGATATTTTTCTTGGCCTCCCTTTCAATATCGCTAGTTATGCACTGCTCACCCATAT
GTTGGCTCAGGTGACTGGGCTCGTGGTCGGTGATTTTGTGCATACGTTGGGTGATGCACATTTGTATGCGAATCATGTCG
AGCAAGCATCCGTGCAACTGGGGCGTGTGCCGCGACCGCAACCGGTATTAAGGCTTAATCAGGCAGTGACTGACTTGTTC
GACTTTACCTACGATGACATTGTGATTGAAGGTTACGATCCATATCCGGCTATCAAGGCACCGGTGGCTGTGTGA

Protein sequence :
MKQYLELLNDVLVHGIQKPDRTGTGTRSVFGWQMRFDLSQGFPLVTTKKLHLRSIIHELLWFLRGETNIAYLKKHQVHIW
DEWADATGELGPVYGKQWRRWAGADGHEIDQIRWLVEEIKRNPDSRRLVISAWNVADLPQMALVPCHALFQFYVANGKLS
CQLYQRSADIFLGLPFNIASYALLTHMLAQVTGLVVGDFVHTLGDAHLYANHVEQASVQLGRVPRPQPVLRLNQAVTDLF
DFTYDDIVIEGYDPYPAIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 2e-77 59