Gene Information

Name : Xfasm12_1327 (Xfasm12_1327)
Accession : YP_001775889.1
Strain : Xylella fastidiosa M12
Genome accession: NC_010513
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 1386130 - 1386903 bp
Length : 774 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAGTCTCGAAATCGTGCCTTTTGTAGTTGCTATTCCCGCACGTTTTTCCGCATCACGACTGCCTGGAAAACCGCTGCG
CCTCCTTGGTGGTCGCCCACTGATTCACAGGGTAGCCGAGCGGGCACTTAGTGCAGGGGCACGGGAAGTATGGGTTGCAA
CCGACGATGTACGCATCGCTGAGGCCGTTGCTTCTCTGGACGGTGTCCACGTGGCGATAACCGCAAACACTCACCTATCC
GGGAGCGACCGCTTAGCCGAGTGCGCACGCATCGCCGGATGGGATCCTGAGGTGTGCGTGGTCAACCTACAGGGCGATGA
GCCGTTCGCACCAGCGGCGGGGATCCGTGCTGTAGCGGCATTGCTGCATCACAGCAACGCCGACATGGCAACGCTCGCAA
CGACCATCGACAAGAGCGAAGACCTGTTCAACCCGAACATCGTCAAACTAGTGTGCAATGCACATGGAGAAGCGTTGTAC
TTCAGCCGTGCACCGATCCCATGGAATCGGGATACCTTCGCCACAACGCGTGAACCAACGCCATTGGGTCCGTGGCTACG
CCACATCGGTCTCTATGCCTGCAACGCTGGGTTCCTGCAACGCTTCACCACGATGCAACCGGGGACCTTGGAGCAGATTG
AATCGTTGGAACAACTGCGTGTGCTGGAAGCAGGGCATCGGATCGCGGTCAGGATCACTCCGGAACATTTCCCGCCCGGT
ATCGATACCCCAGAAGACTTAGCCAAAGCCGAGAAGGCGTTGGAGGATGTATGA

Protein sequence :
MSLEIVPFVVAIPARFSASRLPGKPLRLLGGRPLIHRVAERALSAGAREVWVATDDVRIAEAVASLDGVHVAITANTHLS
GSDRLAECARIAGWDPEVCVVNLQGDEPFAPAAGIRAVAALLHHSNADMATLATTIDKSEDLFNPNIVKLVCNAHGEALY
FSRAPIPWNRDTFATTREPTPLGPWLRHIGLYACNAGFLQRFTTMQPGTLEQIESLEQLRVLEAGHRIAVRITPEHFPPG
IDTPEDLAKAEKALEDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 2e-26 43
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-26 43
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 1e-26 43