Gene Information

Name : hemC (Xfasm12_1258)
Accession : YP_001775827.1
Strain : Xylella fastidiosa M12
Genome accession: NC_010513
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1325456 - 1326373 bp
Length : 918 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGCCTTTACTTCGTATTGCTACTCGCAAAAGTTTACTTGCTATGCGGCAAAGCGAGTATGTCGCTGCGCGTTTACGTAT
GCTGTGCCCTGATTTAGATGTGGTGTTGGTGCCGATGAGCACTCGTGGCGATGAGATCCTGGACCGCTCCCTGGCTGCAA
TTGGTGGTAAAGGGCTGTTTCTCAAGGAGCTGGAACTGGCGATGTTACGTGGTGATGCTGATTGCGCGGTGCATTCGCTG
AAAGATGTGCCTATGGATTTGGAGCCCCCATTTATGCTTGCGGCTGTTTTGAGTCGTGATGACCCGGCCGATGCGCTGAT
TTCTAATGTCTACCTTTCGCTAGAGTCACTCCCAATTGGGGCGCGTGTGGCGACTTCTTCGCTGCGCCGACAAGCCCAGT
TACGCTTTTATCGGCCTGACCTGCGGTTGTTTGACTTGCGGGGTAACGTTAACACGCGCTTGGCGAAGCTTGATAACGGA
GATTACGATGCGATTGTGCTGGCTTGTGCGGGGTTACGTCGGCTGGGATTGGAGCAACGCATGACGGCTCGGCTAGCACC
GCCAGAATGGTTACCTGCGCCAGGTCAGGGGGCGATTGCGGTGGAGTCACTGACCGAGGATGCTCGGATCGGTACGTTGT
TGGCTGGTCTTGACGATCTGCCAACGCGCCAATGCGTGGTGGCTGAGCGTACGATGAATCGTGCTCTTCATGGTAGCTGC
CATGTGCCAGTGGGGGCTTATGCATCCTACGGAGTTGGTGGTATGCGATTACAGGGCTTGGTGGGTTGTGTTGCCGATGG
TCGTCTCGTGCGTGCGGAGCTGTGTTCGGCAAAGGATGAGGGCGATATGCTCGGCAGGGCAGTCGCACAGTGCTTGTTGG
ATGCTGGTGCGGCTGAGTTGCTAGCCGCCACTGCATAG

Protein sequence : 
MPLLRIATRKSLLAMRQSEYVAARLRMLCPDLDVVLVPMSTRGDEILDRSLAAIGGKGLFLKELELAMLRGDADCAVHSL
KDVPMDLEPPFMLAAVLSRDDPADALISNVYLSLESLPIGARVATSSLRRQAQLRFYRPDLRLFDLRGNVNTRLAKLDNG
DYDAIVLACAGLRRLGLEQRMTARLAPPEWLPAPGQGAIAVESLTEDARIGTLLAGLDDLPTRQCVVAERTMNRALHGSC
HVPVGAYASYGVGGMRLQGLVGCVADGRLVRAELCSAKDEGDMLGRAVAQCLLDAGAAELLAATA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-51 52
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-51 52