Gene Information

Name : guaA (M446_0964)
Accession : YP_001767943.1
Strain : Methylobacterium sp. 4-46
Genome accession: NC_010511
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1088286 - 1089842 bp
Length : 1557 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACGGCCGACCACGACAAGATCCTGATCATCGATTTCGGGAGCCAGGTGACCCAGCTCATCGCGCGCCGGGTGCGCGA
GGAGGGGGTCTATTCCGAGATCGTGCCCTACCAGGCGGCGGAGGCGGCCTTCGCGGCCCTGAAGCCGAAGGGCGTGATCC
TCTCGGGCGGCCCCGAATCCGTGACGATCGAGACCTCGCCCCGCGCGCCCCAGGCGGTGTTCGAGGCCGGGGTGCCGGTG
CTCGGCATCTGCTACGGCGAGCAGACCATGGCGGCCCAGCTCGGCGGCGAGGTCGAGGGCGGGCACCACGCCGAGTTCGG
CCGGGCCGAGGTCGAGGTCATCGCCGACTCGGCCCTGTTCCGCGGCATCTGGCACGTGGGCGAGCGCTACCCGGTCTGGA
TGAGCCACGGCGACCGGGTGACCAAGCTGCCGGACGGCTTCTCCACCATCGCGATCTCGCCGAACGCGCCCTTCGCGGCG
GTGGCCGACGAGGGGCGCCGCTTCTACGCGGTGCAGTTCCACCCGGAGGTGGCGCACACGCCGCACGGCGCGCTGCTGCT
GCGCAACTTCGTGCGCGACATCGTGGGCTGCGCGGGCGACTGGTCGATGCGCGCGTTCCGCGAGGAGGCGATCGAGCGCA
TCCGCCGGCAGGTCGGCGGCGAGAAGGTGCTGTGCGGCCTCTCGGGCGGGGTCGACTCGGCGGTGGCGGCGGTGCTGATC
CACGAGGCGATCGGCGAGCAGCTCACCTGCGTGTTCGTGGATCACGGCCTTCTGCGGCTCGGCGAGGCCGAGGAGGTGGT
GCGGCTGTTCCGCGACCACTACAACATCCCGCTCGTGCACGTGCAGGCCCAGGACCTCTTCCTGGGCGCGCTCGCCGGCG
TCACCGACCCGGAGGTGAAGCGCAAGACGATCGGGCGGCTCTTCATCGACGTGTTCGAGGCGGAGGCGAGGAAGAGCGGC
GGCGCGGCGTTCCTGGCGCAGGGCACGCTCTATCCGGACGTGATCGAGAGCGTGTCCTTCACGGGCGGCCCCTCGGTGAC
GATTAAGAGCCACCACAATGTCGGCGGCCTGCCCGAGCGCATGAACATGAAGCTCGTGGAGCCCCTGCGCGAATTGTTCA
AGGACGAGGTGCGGGTGCTCGGCCGCGAGCTCGGCCTGCCCGACGCCTTCGTGGGCCGCCACCCCTTCCCGGGTCCCGGC
CTCGCCATCCGCTGCCCGGGCGAGATCACGGCGGAGAAGCTCGACGCGCTGCGCAAGGCCGACGCGATCTACCTGGAGGA
GATCCGCAAGGCGGGCCTCTACGACACGATCTGGCAGGCCTTCGCGGTGATCCTGCCGGTGAAGACGGTCGGCGTGATGG
GCGACGGGCGCACCTACGACCACGTCTGCGCGCTGCGCGCCGTCACCTCGGTGGACGGCATGACGGCGGATTTCTACCCC
TTCGACATGGGCTTCCTGGGCCGGGTCGCGACCCGGATCATCAACGAGGTCAAGGGCATCAACCGGGTCACCTACGACAT
CACCTCGAAGCCGCCCGGGACGATCGAGTGGGAGTGA

Protein sequence :
MTADHDKILIIDFGSQVTQLIARRVREEGVYSEIVPYQAAEAAFAALKPKGVILSGGPESVTIETSPRAPQAVFEAGVPV
LGICYGEQTMAAQLGGEVEGGHHAEFGRAEVEVIADSALFRGIWHVGERYPVWMSHGDRVTKLPDGFSTIAISPNAPFAA
VADEGRRFYAVQFHPEVAHTPHGALLLRNFVRDIVGCAGDWSMRAFREEAIERIRRQVGGEKVLCGLSGGVDSAVAAVLI
HEAIGEQLTCVFVDHGLLRLGEAEEVVRLFRDHYNIPLVHVQAQDLFLGALAGVTDPEVKRKTIGRLFIDVFEAEARKSG
GAAFLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMNMKLVEPLRELFKDEVRVLGRELGLPDAFVGRHPFPGPG
LAIRCPGEITAEKLDALRKADAIYLEEIRKAGLYDTIWQAFAVILPVKTVGVMGDGRTYDHVCALRAVTSVDGMTADFYP
FDMGFLGRVATRIINEVKGINRVTYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-128 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-128 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-128 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-115 51