Gene Information

Name : M446_6577 (M446_6577)
Accession : YP_001773267.1
Strain : Methylobacterium sp. 4-46
Genome accession: NC_010511
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 7234020 - 7235327 bp
Length : 1308 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCACGACATCCGGGTCATCCGCGACAATCCCGCCGCCTTCGACGCCGGGCTGCGCCGGCGCGGGCTGGAACCGCTCGC
CGCCGAGCTCGTCGCCCTCGACGATGCCCGCAAGGCGGCGATCTCGGCCGCGCAGGTCGCCCAGGAGCGGCGCAACGCCC
TCTCGAAGGAGATCGGCGCGGCCAAGAAGGCGCGGGACGAGGAGCGGGCCCGGGCGCTGATGGCGGAGGTCGCGCGGCTC
AAGGAGCAGGCGCCGGGCCTCGACGCCGCGGCCGACGCCGCCGCGAGGGCCCTCGACGCCCGCCTCGCGGCGATCCCGAA
CACCCCCGGGCCCGAGGTGCCGGAGGGGAGGGACGAGCACGACAACGTCGAGCTTCGCCGCTTCGAGGGGCGCGGCCGGG
CCGAGAGCGGGCGCCAGCACTTCGAACTCGGCGAGGCCGCGGGCCTGATGGATTTCGAGGCCGCCGCCCGGCTGTCGGGC
TCGCGCTTCGTCGTGCTGAAGGGCCGCCTCGCCCGGCTGGAGCGGGCGCTGGGCCAGTTCATGCTCGACCTGCACACCGC
CGAGCACGGCTACACCGAGGTCGCGCCGCCGCTCCTGGTGCGCGACGAGGCGATGTTCGGCACCGCCCAATTGCCGAAAT
TCCGCGACGACCAGTTCGCCGCGCAGCCCGGCGCGGTCGAGCCCGGGGCGCCGGGGCGCTGGCTCATCCCCACCGCCGAG
GTGCCGCTCACCAACCTCGTGCGCGAGAGCATCCTGTCCGAGGACGAGCTGCCCCTGCGCTTCACCGCGCTGACGCCCTG
CTTCCGGGCCGAGGCCGGGGCGGCGGGGCGCGACACCCGCGGCATGCTGCGCCAGCACCAGTTCACCAAGGTCGAACTCG
TCTCGATCACGGCGCCCGAGCAATCCGCCGAGGAGCACGAGCGCATGCTCGCCTGCGCGGAGGCCGTGCTGCGCCGGCTC
GACCTGCCCTACAGGGTGATGACGCTGTGCACCGGCGACATGGGCTTCGCCTCGCAGAAGACCTACGACATCGAGGTCTG
GCTGCCGGGGCAGGGGACCTACCGGGAGATCTCGTCCTGCTCGGTCTGCGGCGATTTCCAGGCCCGGCGCATGGAGGCCC
GCTTCCGCCGCCGGGAGGATCGCGGCCTCGGCTACGTGCACAGCCTCAACGGGTCGGGGGTGGCGGTCGGCCGCGCCCTC
ATCGCCGTGATGGAGAATTACCAGAACCCGGACGGCAGCGTCACGGTGCCGTCCGCGCTCGCGCCCTACATGGGGGGCGT
CACGCGAATCGAGGGACCACACGCCTGA

Protein sequence :
MHDIRVIRDNPAAFDAGLRRRGLEPLAAELVALDDARKAAISAAQVAQERRNALSKEIGAAKKARDEERARALMAEVARL
KEQAPGLDAAADAAARALDARLAAIPNTPGPEVPEGRDEHDNVELRRFEGRGRAESGRQHFELGEAAGLMDFEAAARLSG
SRFVVLKGRLARLERALGQFMLDLHTAEHGYTEVAPPLLVRDEAMFGTAQLPKFRDDQFAAQPGAVEPGAPGRWLIPTAE
VPLTNLVRESILSEDELPLRFTALTPCFRAEAGAAGRDTRGMLRQHQFTKVELVSITAPEQSAEEHERMLACAEAVLRRL
DLPYRVMTLCTGDMGFASQKTYDIEVWLPGQGTYREISSCSVCGDFQARRMEARFRRREDRGLGYVHSLNGSGVAVGRAL
IAVMENYQNPDGSVTVPSALAPYMGGVTRIEGPHA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 5e-80 47