Gene Information

Name : M446_0523 (M446_0523)
Accession : YP_001767520.1
Strain : Methylobacterium sp. 4-46
Genome accession: NC_010511
Putative virulence/resistance : Resistance
Product : arsenical resistance protein ArsH
Function : -
COG functional category : R : General function prediction only
COG ID : COG0431
EC number : -
Position : 620066 - 620809 bp
Length : 744 bp
Strand : +
Note : TIGRFAM: arsenical resistance protein ArsH; PFAM: NADPH-dependent FMN reductase; KEGG: mex:Mext_3863 arsenical resistance protein ArsH

DNA sequence : 
GTGGACAAGCCCCTTCAGCCCTTCGCCGACGGCCTCCCGAACCTCGCCGAGGCCCATTTCGCGGTGCCGAGCCCGGCGGC
GCTGGAGCCCGGCCGGCACCTGACGCACGCGCCGCGCTTCCTGATCCTGTACGGCTCCCTGCGCGAGCGCTCGTTCAGCC
GCCTCCTCGCCTACGAGGCGGCCCGGCTCCTGGAGCGGATGGGCGGGGAGGTGCGGATCTACCACGCGCACGGCCTGCCC
CTGCCGGACGACGCGCCGGCCGATCACCCCAAGGTGCAGGAACTGCGGGCGCTCTCGCTCTGGTCGGAGGGGCAGGTCTG
GGTGAGCCCGGAGCGGCACGGCGCCCTGACCGGCGTGATGAAGAGCCAGATCGACTGGCTGCCCCTGGCCGAGGGGGCGC
TGCGCCCGACCCAGGGGCGCACCCTCGCCGTCATGCAGGTCTCGGGCGGGTCGCAATCCTTCAACGCCGTCAACGCCCTG
CGCGTGCTCGGGCGCTGGATGCGGATGATCACCATCCCCAACCAGTCCTCGGTGCCGATGGCCTACCGGGAATTCGACGA
GGCGGGGCGGATGCGGCCCGGCCCGCTCTACGACCGGGTCGTCGACGTCTGCGAGGAACTGGTCAAGTTCACCCTCCTGA
CCCGCGATCGGGCCGAGTACCTCGTCGACCGCTACAGCGAGCGCAAGGAGCGCGCCCCCGAGCGGCTGCGGGCGGTCGAG
GCGGAGATCGGGACGGGGCGCTGA

Protein sequence : 
MDKPLQPFADGLPNLAEAHFAVPSPAALEPGRHLTHAPRFLILYGSLRERSFSRLLAYEAARLLERMGGEVRIYHAHGLP
LPDDAPADHPKVQELRALSLWSEGQVWVSPERHGALTGVMKSQIDWLPLAEGALRPTQGRTLAVMQVSGGSQSFNAVNAL
RVLGRWMRMITIPNQSSVPMAYREFDEAGRMRPGPLYDRVVDVCEELVKFTLLTRDRAEYLVDRYSERKERAPERLRAVE
AEIGTGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BCAM0236 YP_002232867.1 putative NADPH-dependent FMN reductase Not tested BcenGI11 Protein 2e-67 71
arsH YP_001007636.1 putative arsenic resistance protein Not tested YAPI Protein 7e-61 67
arsH AFC76432.1 ArsH Not tested AbaR5 Protein 3e-59 62
arsH CAJ77015.1 arsenic resistance protein Not tested AbaR1 Protein 2e-59 62
arsH ADZ05766.1 arsenic resistance protein Not tested AbaR11 Protein 2e-59 62

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
M446_0523 YP_001767520.1 arsenical resistance protein ArsH BAC0595 Protein 3e-55 65
M446_0523 YP_001767520.1 arsenical resistance protein ArsH BAC0034 Protein 2e-57 62