Gene Information

Name : M446_3453 (M446_3453)
Accession : YP_001770272.1
Strain : Methylobacterium sp. 4-46
Genome accession: NC_010511
Putative virulence/resistance : Resistance
Product : O-succinylhomoserine (thiol)-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 3839193 - 3840359 bp
Length : 1167 bp
Strand : +
Note : KEGG: swi:Swit_3154 O-succinylhomoserine (thiol)-lyase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein

DNA sequence :
GTGGCGGCACAGCGCAGGGCGGCAGAGACGATCGCGGCGGCGAACGGGATCGGAGCCGACGCGGCTTTCGGCGCCGTCGC
CCCGCCCCTCTACCTCTCGACCACCTACACCTTCGCGGAGTTCGAGACGCCGCGCGGCTACGATTACGCGCGCCTCGGCA
ATCCGACCCGCGACCAGCTCGCCGACACCATCGCCAAGCTCGAGGGCGGCGCCCGCGCCGTCGTGACGGCGAGCGGCATG
GCGGCCCTCGACCTCGCGCTGTCGCCGCTGTCGCCCGGGGACCTCCTGGTCGCCCCGCACGATTGCTACGGCGGCACCCA
CCGGCTGCTCTCCCTGCGCGCCGCCAAGGGGCATTACCGCGTCGCCTTCGTGGACCAGACCGACGCGGCGGCCCTGTCCG
CCGCCCTGGCGGAGCGGCCCCGCATCCTGCTCACCGAGACCCCCAGCAACCCGCTGATGCGGATCGTGGATCTCGGCCGC
ACGGCCGCCCTCGCGCGGGAGGCGGGCGCCCTCTTCGTGGTCGACAACACCTTCCTGTCCCCCGCCCTGCAGCAGCCGAT
CGCGCACGGGGCCGACCTCGTGGTCCATTCCACCACGAAGTTCATCAACGGCCACTCGGACGTGATCGGCGGCGCCGTCG
TGGCGGCGCAGGCCGCCCTCGGCGAGGAGCTCGCCAACTGGGCCAACACGATCGGCGTGACCGGCTCGCCCTTCGACGCC
TACCTGACCCTGCGCGGCCTGCGCACGCTGTTCGCGCGGCTGGAGCGCCAGCAGCAGAGCGCGGCCGTCGTCGCGTCCTT
CCTGGCGGCGCATCCGGCGGTGGCCCGGGTCCATTATCCGGGCCTGCCCGACCACCCGGGCCACGCGGTCGCGCGCGCGC
AGCAGCGCGGGTTCGGCGCCATGCTGAGCTTCGAGCTCGCCGGCGGGCGCGAGGCCGTCCGCACCCTCGTCGGGGCCCTG
CGGGTGTTCACGCTGGCGGAATCGCTCGGCGGGATCGAGAGCCTGATCGCCCATCCGGTGAGCATGACGCACGCCGCCAT
GGCTCCCGAGGCGCGCCGGGCGGCGGGCGTCGGCGACGGGCTGCTGCGGCTCTCGGTCGGGCTCGAGGCCGAAAGCGACC
TCCTCGCCGACCTCGCCGTGGCCCTCGATGCCGCCGCCCGCGGCTGA

Protein sequence :
MAAQRRAAETIAAANGIGADAAFGAVAPPLYLSTTYTFAEFETPRGYDYARLGNPTRDQLADTIAKLEGGARAVVTASGM
AALDLALSPLSPGDLLVAPHDCYGGTHRLLSLRAAKGHYRVAFVDQTDAAALSAALAERPRILLTETPSNPLMRIVDLGR
TAALAREAGALFVVDNTFLSPALQQPIAHGADLVVHSTTKFINGHSDVIGGAVVAAQAALGEELANWANTIGVTGSPFDA
YLTLRGLRTLFARLERQQQSAAVVASFLAAHPAVARVHYPGLPDHPGHAVARAQQRGFGAMLSFELAGGREAVRTLVGAL
RVFTLAESLGGIESLIAHPVSMTHAAMAPEARRAAGVGDGLLRLSVGLEAESDLLADLAVALDAAARG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-42 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
M446_3453 YP_001770272.1 O-succinylhomoserine (thiol)-lyase BAC0207 Protein 3e-38 41