Gene Information

Name : M446_3206 (M446_3206)
Accession : YP_001770046.1
Strain : Methylobacterium sp. 4-46
Genome accession: NC_010511
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 3549433 - 3551316 bp
Length : 1884 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAACGCCCCCGTCATTCCCCCCAAAGGCCTGCCGCAGAGCGTGACCACGGGACCGATCGCCGGCTCCGTCAAGGTCTA
TGCCAGTCCCGAGGGGCGGCCTGACATCCGGGTGCCGCTGCGCGAGATCGCCCTCAGCGATCCGGCCGAGGCGCCGGTGC
GCGTCTACGATCCCTCGGGCCCCTACACGGAGAGCGACGCCAAGGTCGACCTCGCGGCCGGCCTGCCCCAGCTGCGCGAT
CCCTGGATCGCCGGCCGCGGCTACGCCGCGGTGACGCCCCGCGCGGTCAAGCCGGAGGATAACGGCTTCGCGGCCGAGGA
CAGGCTGGTCGCCCCCTGCCCGGCCGCGCGCACGATCCGCAGGGCCGCTCCCGGCCAGATGGTGACCCAGTACGAGTTCG
CCCGGGCCGGGATCGTCACCGAGGAGATGATCTACGTCGCCCACCGGGAGAATCTCGGCCGCCGGGCGATGCTGGACCAG
GCCGAGGCCAAGCTCGCCGACGGCGAGAGCTTCGGCGCGGCGATTCCGCCCTTCATCACCCCGGAATTCGTGCGCGACGA
GATCGCCCGCGGCCGCGCCATCATCCCGGCCAACATCAACCACACCGAACTCGAGCCGATGGCCATCGGCCGCAACTTCC
TGGTCAAGATCAACGCCAATATCGGCAACTCGGCCGTGACCTCCTCGGCGGCCGAGGAGGTCGAGAAGATGGTCTGGGCG
ACCCGCTGGGGCGCCGACACCGTCATGGACCTGTCGACGGGCCGCAACATCCACAACATCCGCGGCTGGATCCTGCGCAA
CGCGCCGGTGCCGATCGGGACCGTGCCGATCTACCAGGCCCTGGAGAAGGTCGGGGGCGACCCGCTGAAACTCGACTGGG
AGGTGTTCAGGGACACGCTCATCGAGCAGGCCGAGCAGGGGGTCGACTACTTCACCATCCATGCGGGCGTGCGGCTCGCC
CACGTGCCGCTGACCGCGCGGCGGGTCACCGGCATCGTCTCGCGCGGCGGCTCGATCATGGCCCGCTGGTGCCTCGCCGG
CCACCGGGAATCGTTCCTCTACGAGCGGTTCGACGAGATCTGCGAGATCATGCGCGCCTACGACGTCTCCTTCTCGCTCG
GGGACGGCCTGCGGCCCGGCTCGATCGCCGACGCCAACGACGCGGCGCAATTCGCCGAGCTCGAGACCCTCGGCGAACTC
ACCAAGGTCGCCTGGGAGAAGGGCTGTCAGGTCATGATCGAGGGCCCCGGCCACGTGCCGATGCACAAGATCAAGGTCAA
CATGGAGAAGCAGCTGCGCGAGTGCGGCGAGGCGCCGTTCTACACGCTCGGGCCGCTGACCACCGACGTGGCGCCCGGCT
ACGACCACATCACCTCCGGCATCGGCGCGGCGATGATCGGCTGGTACGGCACCGCGATGCTCTGCTACGTGACCCCCAAG
GAGCATCTCGGCCTGCCGAACCGCGACGACGTGAAGACCGGCGTCATCACCTACAAGATCGCCGCCCACGCCGCCGACCT
CGCCAAGGGCCACCCGGCCGCGCAGCTGCGCGACGACGCCCTGTCCCGGGCCCGGTTCGACTTCCGCTGGGAGGACCAGT
TCAACCTCTCCCTCGACCCGGACACGGCCCGCGCCTACCACGACGAGACGCTGCCCAAGGACGCCCACAAGGTCGCGCAT
TTCTGCTCGATGTGCGGCCCGAAATTCTGCTCGATGAAGATCACGCAGGACCTGCGGGCGGACGTGCTGGCCATGGAGGC
GGCCGGCACCGTGGTGGGCGCCGCCCCCGCGATGAGCGAGGCGGACCGGGCGGCCGGCATGGCGGCCAAGTCGGCCGAGT
TCCTGGCCGAGGGCGGCAAGCTCTACGTCGACGCCGCGGAGTGA

Protein sequence :
MNAPVIPPKGLPQSVTTGPIAGSVKVYASPEGRPDIRVPLREIALSDPAEAPVRVYDPSGPYTESDAKVDLAAGLPQLRD
PWIAGRGYAAVTPRAVKPEDNGFAAEDRLVAPCPAARTIRRAAPGQMVTQYEFARAGIVTEEMIYVAHRENLGRRAMLDQ
AEAKLADGESFGAAIPPFITPEFVRDEIARGRAIIPANINHTELEPMAIGRNFLVKINANIGNSAVTSSAAEEVEKMVWA
TRWGADTVMDLSTGRNIHNIRGWILRNAPVPIGTVPIYQALEKVGGDPLKLDWEVFRDTLIEQAEQGVDYFTIHAGVRLA
HVPLTARRVTGIVSRGGSIMARWCLAGHRESFLYERFDEICEIMRAYDVSFSLGDGLRPGSIADANDAAQFAELETLGEL
TKVAWEKGCQVMIEGPGHVPMHKIKVNMEKQLRECGEAPFYTLGPLTTDVAPGYDHITSGIGAAMIGWYGTAMLCYVTPK
EHLGLPNRDDVKTGVITYKIAAHAADLAKGHPAAQLRDDALSRARFDFRWEDQFNLSLDPDTARAYHDETLPKDAHKVAH
FCSMCGPKFCSMKITQDLRADVLAMEAAGTVVGAAPAMSEADRAAGMAAKSAEFLAEGGKLYVDAAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 65
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 65
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 63