Gene Information

Name : M446_2779 (M446_2779)
Accession : YP_001769650.1
Strain : Methylobacterium sp. 4-46
Genome accession: NC_010511
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 3085230 - 3086750 bp
Length : 1521 bp
Strand : +
Note : PFAM: Aldehyde Dehydrogenase_; KEGG: mex:Mext_3423 aldehyde dehydrogenase

DNA sequence : 
ATGAACAAGCCGGAATTCCTGCGCGGCCAGACCGCCTCGCCGTTCGCGGCGCGCTACGACAACTTCATCGGCGGGCAGTG
GGTGGCGCCGGCGGCGGGGCGCTACTTCGAGAACACGTCGCCGCTCACCGGGCGGCTGATCTGCGAGGTCGCCCGCTCCG
ACGCCCAGGACATCGAGCGCGCCCTCGACGCCGCCCACGCCGCCAAGGACGCCTGGGCCCGCACCGCCCCCGCCGAGCGC
GCCCGCATCCTCACCAGGATGGCCGACCGCATGGAGGACAACCTCGACCTGCTGGCGCTGGCCGAGACCTGGGACAACGG
CAAGCCGATCCGCGAGACCACCCACGCCGACATCCCGCTGGCCATCGACCATTTCCGCTACTTCGCCGGCTGCGTGCGCG
CCCAGGAGGGCTCGCTCTCCGAGATCGACCACGACACCGTCGCCTACCACTTCCACGAGCCGCTCGGCGTGGTCGGCCAG
ATCATCCCGTGGAACTTCCCCATCCTGATGGCGGTCTGGAAGCTCGCCCCGGCCCTGGCGGCCGGCAACTGCGTGGTGCT
CAAGCCCGCCGAGCAGACCCCGGCCTCGGTCCTGGTCCTGGCCGAGATCATCGGCGACCTGCTGCCGGCCGGCGTGCTCA
ACATCGTCAACGGCTTCGGCCTGGAGGCGGGCAAGCCGCTGGCCTCCTCGCCGCGCATCGCCAAGATCGCCTTCACGGGC
GAGACCTCGACCGGGCGGCTGATCATGCAGTACGCCAGCCAGAACCTGATCCCGGTGACGCTGGAGCTGGGGGGCAAGTC
GCCCAACATCTTCTTTGAGGACGTGATGGCGCGGGACGACGCGTTCCTGGACAAGGTGCTGGAGGGCTTCGCGATGTTCG
CCCTCAACCAGGGCGAGGTCTGCACCTGCCCGAGCCGGGCGCTGGTGCAGGAATCGATCTACGAGCGCTTCATCGAGAAG
GCGGTGGCGCGGGTGGAGGCGATCCGGCAGGGCTCGCCGCTCGACCCGGCCACGATGATCGGCGCCCAGGCCTCGGGCGA
GCAGCTGGCCAAGATCCTGTCCTACATCGACATCGGCCGCCAGGAGGGGGCGCAGCTGCTGACCGGCGGCGAGCGGGCGG
TGCTGGCGGGCGAGTTCGCCGAGGGCTTCTACGTGAAGCCGACGGTGTTCCGGGGCCACAACCGGATGCGGATCTTCCAG
GAGGAGATCTTCGGGCCGGTGCTGTCGGTGACGACGTTCAAGGACGAGGCCGAGGCGCTGGCGATCGCCAACGACACGCT
CTACGGGCTGGGCGCCGGGGTGTGGACACGGGACGGGACGCGGGCCTACCGGTTCGGGCGGGAGATCCAGGCCGGCCGGG
TGTGGACGAACTGCTACCACGCCTACCCGGCCCACGCCGCCTTCGGGGGCTACAAGCAGTCGGGCATCGGGCGCGAGACC
CACAAGATGATGCTCGACCACTACCAGCAGACCAAGAACCTCCTGGTCAGCTACTCGCCCAAGGCCCTCGGCTTCTTCTG
A

Protein sequence : 
MNKPEFLRGQTASPFAARYDNFIGGQWVAPAAGRYFENTSPLTGRLICEVARSDAQDIERALDAAHAAKDAWARTAPAER
ARILTRMADRMEDNLDLLALAETWDNGKPIRETTHADIPLAIDHFRYFAGCVRAQEGSLSEIDHDTVAYHFHEPLGVVGQ
IIPWNFPILMAVWKLAPALAAGNCVVLKPAEQTPASVLVLAEIIGDLLPAGVLNIVNGFGLEAGKPLASSPRIAKIAFTG
ETSTGRLIMQYASQNLIPVTLELGGKSPNIFFEDVMARDDAFLDKVLEGFAMFALNQGEVCTCPSRALVQESIYERFIEK
AVARVEAIRQGSPLDPATMIGAQASGEQLAKILSYIDIGRQEGAQLLTGGERAVLAGEFAEGFYVKPTVFRGHNRMRIFQ
EEIFGPVLSVTTFKDEAEALAIANDTLYGLGAGVWTRDGTRAYRFGREIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRET
HKMMLDHYQQTKNLLVSYSPKALGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-147 64
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 4e-153 64
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 4e-153 64
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 4e-153 64
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-152 64
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 9e-69 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
M446_2779 YP_001769650.1 aldehyde dehydrogenase VFG0082 Protein 2e-147 64