Gene Information

Name : M446_1090 (M446_1090)
Accession : YP_001768052.1
Strain : Methylobacterium sp. 4-46
Genome accession: NC_010511
Putative virulence/resistance : Resistance
Product : dihydrofolate reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0262
EC number : 1.5.1.3
Position : 1214994 - 1215485 bp
Length : 492 bp
Strand : -
Note : PFAM: dihydrofolate reductase region; KEGG: mex:Mext_2659 dihydrofolate reductase

DNA sequence :
GTGCCCCGCGTCACCCTGATCGCCGCGGTCGCGCGCAACGGCGTCATCGGCCGCGACAACGACCTCGCCTGGCGCCTGCG
CGGCGACCTGCGGCGCTTCCGCGCCCTCACGATGGGCAAGCCGGTGGTGATGGGCCGCCGGACCTGGGACTCGATTGGCC
GGCCGCTTCCCGGCCGGCGGGTCATCGTGATGACCCGCGATCCCGGCTGGTCGGCGCCCGGCGTCGAGACGGCCGCCGGC
TGGGACGCGGTGCTCGCCCTCGTCGGGGAGGCCGAGGAGGTGATGGTGGCGGGCGGCGCGCAGATCTACGCCCTGACCCT
GCCGCTCGCCGACCGGATCGAACTCACCGAGGTGGCGGCGGCGCCCGAGGGCGACGCGCGCTTCCCCGAGATCCCGGCGG
GCCGCTTCCGGGAGGTCGCGAGCGAGGCGCACCCGGCCGGCCCGGAGGACGAGCATCCCTACCGGTTCGTCACCCTCGAC
CGCCACGTTTGA

Protein sequence :
MPRVTLIAAVARNGVIGRDNDLAWRLRGDLRRFRALTMGKPVVMGRRTWDSIGRPLPGRRVIVMTRDPGWSAPGVETAAG
WDAVLALVGEAEEVMVAGGAQIYALTLPLADRIELTEVAAAPEGDARFPEIPAGRFREVASEAHPAGPEDEHPYRFVTLD
RHV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dfrA12 ACF06156.1 dihydrofolate reductase Not tested Tn5036-like Protein 8e-25 43