Gene Information

Name : Mrad2831_6322 (Mrad2831_6322)
Accession : YP_001766487.1
Strain :
Genome accession: NC_010509
Putative virulence/resistance : Unknown
Product : DNA topoisomerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 19214 - 21580 bp
Length : 2367 bp
Strand : +
Note : KEGG: xfa:XFa0003 topoisomerase I; TIGRFAM: DNA topoisomerase I; PFAM: TOPRIM domain protein; DNA topoisomerase type IA central domain protein; SMART: DNA topoisomerase I ATP-binding; DNA topoisomerase I DNA-binding; Toprim sub domain protein

DNA sequence :
ATGAAGCTCATGGTGGTGGAGAGTCCGAATAAGGTTGCGAGTATCCAAGGTTATCTCGGCGACGATTGGAAGGTGGTCGC
AAGCTCCGGTCATATTCGCGACTTGCCGCAACGCGAATTTGGCATCAGCAAGCCCGATTTTTCCCTTCAGTACGAATATA
TCCCGCCGCAGAAAGTGGGAAATAAGACTTTCCCCGGCGCCGCCGATCGCGTGGCACGGATTAAACGCGAGGTCGCGAAA
GCCGATGCGGTCTACCTGGCGACTGATCCGGACCGCGAGGGCGAAGCGATTTCCTGGCATCTGAAGGAGGCGCTTCAACT
CGGCGAAGACGACTATGAGCGTGTGACGTTCACCGAGATTACGCCGAAGGCGATCCAGGCAGCGCTGCGCGCCGCACGGC
GCATCGACATGGACCTGGTGCATGCCCAGGAAGGGCGGCGCGCCCTGGATCGGTTCGTGGGCTACATGGTGTCGCCGCTG
CTGTCGGACATGCTCGGCATGAACCTGTCCGCCGGCCGCGTTCAGAGCGTGGCGGTGCGCCTGGTGGTGGACCTGGAGCG
CCGTATCGCGGCGTTCAAATCCACCAAGCATTTCAGCGCGGTGGTGACGTTCGACGCCGGCGCCGGCGCGAAATGGTCGG
CGCAGTGGGACACGAAGCCGTATGTGACCGAGGACAGCCCTTATGTGCTGGACGAGGCATTGGCCGCGAAGGCCTCGCAA
TCGCGGCAATTCGTGGTCCTGGAGTCGAAGACGGAAGAGAAGTCGGAACGGCCGCCGTCGCCGCTTTCGACGCTCGGGAT
GCTGCGCGCGGCTAGCACGGCCTTGAAAATGAGTTCTGCCGCGACGACGAAGGCGGCGCAGAAGCTCTTTGAGGACGGCC
ATATCACGTACATCCGCACCGACAGCGTGAACCTGAGTCCGGATGCGGCCGACAAGGTGCGTAGCTTCGCGGCAAGCCAG
GGGATGGCGTTGTCGCCAGAAGTGCGCAGGTGGAAGGAGAAAGCCAGCGCGCAGGGCGGACACGCCGACGCGGTGCGGCC
GACGCACATTGAGGTCGAGGACGCCGGCGCGGACGACGCCCAGCGAGCGCTCTATCGGTTGATCCGGCTGCGCACCCTGG
TGTCGCAGATGGCCGACGCCCGATACACGGTCAATACGGTGCGCCTGCGCGCTACCGATCGCGACGGCTTTGAGTATGTC
GCGCGCGGCCGCAAGATGATCGACGCCGGCTGGCGTGCGCTGCTGGAGCGCGATCCGGACGAGGAAGAGAACAGCGACGA
CGACGCCGCCAAGGACGGCCAGGTTCCACGCCTGGCTGTCGGCGGTGATCTGCGTGCGATCGACGGCAAGGTGTTGGACA
AGAAGACGGAGCCGCCGCGCCGTTTCACTGAAGCAACTTTGCTTCAGAAGCTTGAGGACGAAGGAGTCGGCCGCCCTGCG
ACGTTCGCGGCGATCATGACCAACGTGCTGGGCCGCAGCTACGTCGAGCTGGACAAGAAGCGATGCCTACTGCCGACCGA
GATCGGCGAGCTGGTGGTGGACAATCTGCTGCGCGGCCAGTTCGGTTTCATGGAGCTGGGCTTCACCCGCGAGCTTGAGG
TGCAGCTAGACGCCATCGCCGAAGGCAAGGCGTCGTATCGCGACGTGGTGGAACCGGCCTACAGGCAGTTGAACGAGGAG
CTGGCGCGCATCGCGGTCAGCGGCGAGTTCACGCCCCGCTTCAAATGCCCGAAATGCGGCACGGGCATGCGTCGCTACGC
CAAACCCGGCAAGTCGCCGTTCTGGCGCTGCACGGCCGAGGCCGAGACGTGCGGCCACTACATGGACGACGACAAGGGCA
AGCCGGTCGAGCGAACGGCGCACCCGTGCCCTCGCTGTGGTGAGACCCTACGGCGCTTCAAGCGCAAGAATGGCGGCGGC
CTGGTGTGGGTCTGCCCGGCCGAGGCCTGCGAGACGTTCCTGGACGACGTGGGCGGCAAGCCCGTCGCCCTGCACACCTG
CACCAAGTGCAACGCGCCGCTGCGGCGATACCAGAAGAAGGATCGCGAGACCGGGAAGCCGACAGGCGCATTTGGCTGGT
TCTGCACGGACACCGAGAACTGCAAGACCTTCATGGACGACGACAAGGGCCGGCCCGTCGCGATCAAGACGGCACCGTGC
CCGAAGTGCGGCAAGGCCATGTACCGTCGCAAGGGCGACCATGGCTTTTGGTGGGGCTGTAGCGGCTACCGTGAGGGCTG
CAAGACCATCATGGACGACGACAAGGGCAAGCCCGTGCCGAGGGCGGCAAAGGGCGCCACCAGGTCCAGCAACTCGCCGG
CGAAGGCCAAAGCGAAGCCTGCGGCTAAGCCGAAGATGCGCCGGTAG

Protein sequence :
MKLMVVESPNKVASIQGYLGDDWKVVASSGHIRDLPQREFGISKPDFSLQYEYIPPQKVGNKTFPGAADRVARIKREVAK
ADAVYLATDPDREGEAISWHLKEALQLGEDDYERVTFTEITPKAIQAALRAARRIDMDLVHAQEGRRALDRFVGYMVSPL
LSDMLGMNLSAGRVQSVAVRLVVDLERRIAAFKSTKHFSAVVTFDAGAGAKWSAQWDTKPYVTEDSPYVLDEALAAKASQ
SRQFVVLESKTEEKSERPPSPLSTLGMLRAASTALKMSSAATTKAAQKLFEDGHITYIRTDSVNLSPDAADKVRSFAASQ
GMALSPEVRRWKEKASAQGGHADAVRPTHIEVEDAGADDAQRALYRLIRLRTLVSQMADARYTVNTVRLRATDRDGFEYV
ARGRKMIDAGWRALLERDPDEEENSDDDAAKDGQVPRLAVGGDLRAIDGKVLDKKTEPPRRFTEATLLQKLEDEGVGRPA
TFAAIMTNVLGRSYVELDKKRCLLPTEIGELVVDNLLRGQFGFMELGFTRELEVQLDAIAEGKASYRDVVEPAYRQLNEE
LARIAVSGEFTPRFKCPKCGTGMRRYAKPGKSPFWRCTAEAETCGHYMDDDKGKPVERTAHPCPRCGETLRRFKRKNGGG
LVWVCPAEACETFLDDVGGKPVALHTCTKCNAPLRRYQKKDRETGKPTGAFGWFCTDTENCKTFMDDDKGRPVAIKTAPC
PKCGKAMYRRKGDHGFWWGCSGYREGCKTIMDDDKGKPVPRAAKGATRSSNSPAKAKAKPAAKPKMRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
top ACP28824.1 DNA topoisomerase I Not tested AbaR5 Protein 2e-126 47
topA ADI24145.1 DNA topoisomerase I Not tested AbaR1 Protein 1e-126 47