Gene Information

Name : guaA (Swoo_1560)
Accession : YP_001759941.1
Strain : Shewanella woodyi ATCC 51908
Genome accession: NC_010506
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1940476 - 1942053 bp
Length : 1578 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAACAACATTCATGATCATAAGATACTGATCTTAGATTTTGGCTCTCAGTACACTCAACTTATTGCCCGTCGTATCCG
TGAGATCGGCGTGTATTGTGAACTTTGGGCTTGGGATGTATCCGAAGAACAGATTAAAGAGTTTGCACCAAACGGCATCA
TCTTAGCGGGCGGCCCTGAAAGTGTCACTGCAAAGGATTCACCTCGTGCCCCAGAATACGTTTTCACTGCTGGTGTTCCA
GTACTTGGGATCTGTTACGGCATGCAGACCATGTCTGAACAGCTTGGTGGTAAGGTTATTCAAGGCGTCGGTGAAGGCGA
GTTTGGTTACGCGCAAGTTGAACTTCAGACTCAATCTGAACTGTTTAAAAGCATTGAAGATGCGATCAGTGACTCAGGTA
AGCCTCTGCTAGATGTATGGATGAGTCATGGCGATAAGGTTTCTGAGATCCCAGAAGGTTTTGTGACCGTTGCTAATACA
GAAACTTGCCCATATGCCGCGATGGCTAACGAAGAGAAAAAATTCTACGGTGTTCAGTTCCACCCTGAGGTGACACATAC
TCGTCAGGGTAAGCGTATGCTTGAGCATTTTGCTTTGGATATCTGTCAGTGTGATGCTAACTGGAAGCCAGCGTCTATTA
TCGAAGATGCTATCGAGAGATTGAAGCAGCAGATCGGTGATGATGAAGTTATCTTAGGTCTTTCTGGTGGTGTTGATTCA
TCAGTGGTTGCCATGCTGCTTCACCGCGCAATTGGCGACAAGTTAACTTGCGTGTTTGTTGATAACGGTTTACTACGTCT
TAATGAAGCGCAGCAAGTGATGGATATGTTTGGCGATCACTTTGGATTGAATATTGTCCATGTTGACGCTGAAAACCGTT
TCCTTGATGCGATGGCGGGTGAAGCCGATCCTGAAGCTAAACGTAAAATTATTGGTCATGTTTTTGTTGATATCTTCGAT
GAAGAGTCTAAGAAGTGCGTGAATGCTAAATGGTTAGCGCAGGGCACTATCTACCCAGATGTGATTGAATCAGCGGGTAG
CGCAACAGGCAAAGCCCATGTGATTAAATCACACCATAACGTTGGCGGTCTGCCAGATGATATGGAGATGGGGCTTGTTG
AGCCGCTTCGTGAACTGTTTAAAGATGAAGTACGTAAGATAGGTCTTGAGTTAGGTCTTCCTTATGACATGCTTTACCGT
CATCCTTTCCCTGGACCGGGTTTAGGTGTACGTGTTCTGGGTGAAGTGAAGAAAGAGTACTGTGATCTACTTCGTTTAGC
CGATGCTATCTTTATCGAAGAGCTGCACAAAGCTGACCTTTATAACAAGGTGAGTCAGGCATTTACTGTTTTCCTACCAG
TACGCTCTGTGGGCGTGATGGGTGATGGCCGTAAATATGATTGGGTTGTTTCACTGCGCGCTGTTGAGACAATTGATTTC
ATGACTGCACACTGGGCACATCTACCGTATGACTTCTTAGGTCGCGTATCTAACCGTATCATCAATGAGATCGACGGTAT
CTCACGTGTTGTTTACGATATTTCAGGCAAGCCACCTGCGACGATCGAGTGGGAATAA

Protein sequence :
MNNIHDHKILILDFGSQYTQLIARRIREIGVYCELWAWDVSEEQIKEFAPNGIILAGGPESVTAKDSPRAPEYVFTAGVP
VLGICYGMQTMSEQLGGKVIQGVGEGEFGYAQVELQTQSELFKSIEDAISDSGKPLLDVWMSHGDKVSEIPEGFVTVANT
ETCPYAAMANEEKKFYGVQFHPEVTHTRQGKRMLEHFALDICQCDANWKPASIIEDAIERLKQQIGDDEVILGLSGGVDS
SVVAMLLHRAIGDKLTCVFVDNGLLRLNEAQQVMDMFGDHFGLNIVHVDAENRFLDAMAGEADPEAKRKIIGHVFVDIFD
EESKKCVNAKWLAQGTIYPDVIESAGSATGKAHVIKSHHNVGGLPDDMEMGLVEPLRELFKDEVRKIGLELGLPYDMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRLADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEIDGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-126 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-126 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-126 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 5e-110 48