Gene Information

Name : guaA (Mrad2831_0451)
Accession : YP_001753145.1
Strain : Methylobacterium radiotolerans JCM 2831
Genome accession: NC_010505
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 487066 - 488622 bp
Length : 1557 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAACACCGACCACGACAAGATCCTGATCGTCGATTTCGGCTCTCAGGTGACGCAGCTCATCGCCCGCCGGGTGCGCGA
GGAGGGCGTCTACTGTGAGATCGTGCCCTTCACGAAGGCCGAGGCGGCGTTCCGCGAGCAGAAGCCCAAGGGCGTGATCC
TCTCCGGCGGCCCCGAATCGGTGACCGTGGAGGCATCGCCCCGCGCGCCGCAGCTCGTGTTCGATTCCGGCGTCCCGGTC
TTCGGCATCTGCTACGGCCAGCAGACTATGGCGGCCCAGCTCGGCGGTGCCGTCGAGGGCGGTCACCACGCGGAGTTCGG
CCGCGCCGAGGTCGAGATCCTGGCCGATTGCCCGCTGTTCAAGGGCGTGTGGCACAAGGGCGAGAAGTACCCGGTCTGGA
TGAGCCACGGTGACCGCGTCACCAAGCTGCCGGACGGCTTCACCACCGTGGCGATCTCTCGGAACGCCCCCTTCGCGGCG
GTGGCCGACGAGGCCCGCAACTACTACGCGGTCCAGTTCCACCCGGAGGTGGCGCACACGCCCCACGGCGCCCTGCTGAT
CCGCAACTTCGTGCGCGATGTCGCGGGCTGCTCGGGCGACTGGACCATGGGCGCCTACCGCGAGGAGGCCATCGCCAAGA
TCCGCGAGCAGGTCGGCTCCGAGAAGGTGATCTGCGGTCTGTCTGGCGGCGTCGATTCGGCCGTAGCGGCGGTGCTGATC
CACGAGGCGATCGGCGATCAGCTGACCTGCGTGTTCGTCGACCACGGGCTCCTGCGCCTCGGCGAGGCCGAGCAGGTCGT
GGCTTTGTTCCGCGACCACTACAACATCCCGCTGGTCCACGTGGAGGCGTCGGGGATGTTCCTCGCGGCTCTGGAGGGCG
TCAGCGACCCGGAAATCAAGCGCAAGACGATCGGCCGCCTGTTCATCGACGTGTTCGAGGCCGAATCGAAGAAGATCGGC
GGGGCGAAGTTCCTCGCGCAGGGCACGCTCTACCCCGACGTGATCGAGAGCGTGTCGTTCACGGGCGGCCCGTCGGTGAC
GATCAAGAGCCACCACAATGTCGGCGGCCTGCCCGAGCGCATGAACATGAAGCTCGTCGAGCCGCTGCGCGAGCTGTTCA
AGGACGAGGTCCGGGTGCTCGGCAAGGAGCTCGGCCTGCCCGAGGGCTTCGTCGGCCGCCACCCGTTCCCGGGCCCGGGC
CTGGCGATCCGCTGCCCCGGCACCATCACGGGTGAGAAGCTGGAAGCCCTGCGCAAGGCCGACGCGATCTACCTCGACGA
GATCCGGCAGGCCGGCCTCTACGACACGATCTGGCAGGCCTTCGCGGTGATCCTGCCGGTGAAGACTGTCGGCGTGATGG
GCGACGGCCGCACCTATGACCATGTCTGCGCGCTGCGCGCCGTCACCTCGGTCGATGGCATGACCGCCGACTTCTACCCG
TTCGACATGGCCTTCCTGGGCCGGGTCGCGACTCGTATCATCAACGAGGTGAAGGGCATCAACCGGGTGACCTACGACAT
CACCTCCAAGCCGCCCGGCACGATCGAGTGGGAGTGA

Protein sequence :
MNTDHDKILIVDFGSQVTQLIARRVREEGVYCEIVPFTKAEAAFREQKPKGVILSGGPESVTVEASPRAPQLVFDSGVPV
FGICYGQQTMAAQLGGAVEGGHHAEFGRAEVEILADCPLFKGVWHKGEKYPVWMSHGDRVTKLPDGFTTVAISRNAPFAA
VADEARNYYAVQFHPEVAHTPHGALLIRNFVRDVAGCSGDWTMGAYREEAIAKIREQVGSEKVICGLSGGVDSAVAAVLI
HEAIGDQLTCVFVDHGLLRLGEAEQVVALFRDHYNIPLVHVEASGMFLAALEGVSDPEIKRKTIGRLFIDVFEAESKKIG
GAKFLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMNMKLVEPLRELFKDEVRVLGKELGLPEGFVGRHPFPGPG
LAIRCPGTITGEKLEALRKADAIYLDEIRQAGLYDTIWQAFAVILPVKTVGVMGDGRTYDHVCALRAVTSVDGMTADFYP
FDMAFLGRVATRIINEVKGINRVTYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-130 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-130 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-130 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 9e-117 51