Gene Information

Name : Mrad2831_4408 (Mrad2831_4408)
Accession : YP_001757057.1
Strain : Methylobacterium radiotolerans JCM 2831
Genome accession: NC_010505
Putative virulence/resistance : Resistance
Product : O-succinylhomoserine (thiol)-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 4676403 - 4677563 bp
Length : 1161 bp
Strand : -
Note : KEGG: nha:Nham_0684 O-succinylhomoserine (thiol)-lyase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein

DNA sequence : 
ATGTCAGAGGGATTAGCGGCGCGTACCGTCGCGGCGGCCAACGGCGTGGCCCAGGACGCGGCCTTCGGCGCGGTGATCGC
GCCGATCCACCTGTCGACGACCTTCAAGTTCCCGGCCTTCGAGCAGCCCGGCCCCTACGATTACTCGCGCCTGGGCAACC
CGACCCGGGACGCGCTGGCCGACACGATCGCCAAGCTCGAGGGCGGCGCCCGCGCCGTCCTGGTGGCGAGCGGCATGGCG
GCCCTCGACCTCGCCCTGTCGAGCCTGCGGCCCGGCGATCTCTTGGTCGCGCCGCACGATTGCTACGGCGGGACGCACCG
CCTGCTCAGCTTCCGCGCGGAGCGGGGCCATTACCGCGTCGCCTTCGTCGACCAGACCGATCCGGACGCGCTGGCGGCGG
CCCTGGCCCAGGGGCCGAAGGTCGTGCTGATCGAGACGCCCAGCAACCCGCTGATGCGCGTGGTCGATGTCCGGCGCATC
ACCGCAGACGCGAAGGCGGCCGGCGCGCTGGCTGTGGTGGACAACACCTTCCTGTCGCCCGCCCTGCAGCAGCCGATCGC
CCTCGGGGCGGATCTGGTCGTCCATTCCACCACCAAGTTCCTGAACGGCCATTCCGACGTGATCGGCGGGGTGGTGATCG
CCGCCGACAAGGCGGTGGGCGAGGACCTCGCCGCCTGGGCGAACACGATCGGCGTCACCGGCTCGCCCCTCGACGCCTAC
CTGACGCTCCGGGGCCTGCGCACCCTGTTCGTGCGGGTGGAGCAGCAGCAGCGCAACGCCGCCGCCCTGGCGGCTTTTCT
GGATGCCCATCCGGCGGTGGCCCGGGTGCATTATCCCGGCCTGCCCACGCATCCGGGGCACGCCCTGGCCAAGGCGCAGC
AGGCAGGCTTCGGGGCGATGCTGAGCTTCGAGCTGGCCGGCGGCCGCGCGGCGGTGAAGACCTTCGTCGAGGCCCTGCGG
GTGTTCACGCTGGCCGAGTCGCTCGGCGGCGTCGAGAGCCTGATCGCCCATCCGCCGACCATGACGCACGCGGCGATGGA
CCTGGAGGCGCGCGCCATCGCGGGCATCACCGACGGGCTGCTGCGCCTGTCGGTCGGCCTGGAGGCGGAGGCCGACCTGC
TGGCCGACCTGTCGCGGGCCTTCCAGGCCCTGGACGGCTGA

Protein sequence : 
MSEGLAARTVAAANGVAQDAAFGAVIAPIHLSTTFKFPAFEQPGPYDYSRLGNPTRDALADTIAKLEGGARAVLVASGMA
ALDLALSSLRPGDLLVAPHDCYGGTHRLLSFRAERGHYRVAFVDQTDPDALAAALAQGPKVVLIETPSNPLMRVVDVRRI
TADAKAAGALAVVDNTFLSPALQQPIALGADLVVHSTTKFLNGHSDVIGGVVIAADKAVGEDLAAWANTIGVTGSPLDAY
LTLRGLRTLFVRVEQQQRNAAALAAFLDAHPAVARVHYPGLPTHPGHALAKAQQAGFGAMLSFELAGGRAAVKTFVEALR
VFTLAESLGGVESLIAHPPTMTHAAMDLEARAIAGITDGLLRLSVGLEAEADLLADLSRAFQALDG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-49 44
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-48 43
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-47 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mrad2831_4408 YP_001757057.1 O-succinylhomoserine (thiol)-lyase BAC0207 Protein 2e-47 42