Gene Information

Name : Mrad2831_3185 (Mrad2831_3185)
Accession : YP_001755850.1
Strain : Methylobacterium radiotolerans JCM 2831
Genome accession: NC_010505
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 3362386 - 3364272 bp
Length : 1887 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAACGCACCCGTTCTCCCGAAGGACGTGAAAGGCAGCCCCGAGACCGTGACCACGGGTCCGGTGACCGGATCGCGCAA
GGCCTACGCGAGCCCGGCCGGGCGGCCGGACATCCGCGTACCCTACCGCGAGATCGTCCTCTCCGATCCGAAGGAGGAGC
CGGTGCGGGTCTACGACCCGTCGGGCCCCTACACGGAGACCGATGCCCGCATCGACCTCAACGCCGGCCTCCCCGGCGTG
CGCGAGCCCTGGATCGCGGCGCGCGGCTACGCGTCCGTCGCCCCGCGCGCGGTGAAGCCCGAAGATAACGGTTTCGCGGG
CGACAAGCTCGTGGCCCCCTGCCCGGCCGAGCGGACCGTCCGCAAGGCGGCCCCGGGCCAGATGGTGACCCAGTACGAGT
TCGCCCGCGCGGGGATCATCACCGAGGAGATGATCTACGTCGCCCATCGCGAGAACGTCTGCCGCGAGGCGATGCTCGCG
GGCGCCGAGGCCGCGCTCGCCGACGGCCAGAGCTTCGGGGCCTCGGTCCCGCCCTTCATCACCCCGGAATTCGTGCGCGA
CGAGATCGCCCGCGGCCGGGCGATCATCCCGGCCAACATCAACCACACCGAGCTGGAGCCGATGGCGATCGGCCGGAACT
TCCTGGTCAAGATCAACGCCAATATCGGCAACTCGGCCGTGACCTCCTCGGCGGCCGACGAGGTCGAGAAGCTCGTCTGG
TCGATCCGCTGGGGCGCCGACACGGTCATGGACCTGTCCACCGGCCGCAACATCCACAATATCCGCTCGTGGATCATCCG
CAACAGCCCGGTTCCGATCGGCACGGTGCCGATCTACCAGGCGCTGGAGAAGGTCGGCGGCGACCCGCTGAAGCTCGACT
GGGAGGTCTTCAAGGACACGCTGATCGAGCAGGCCGAGCAGGGCATCGACTACTTCACCATCCATGCCGGCGTGCGGCTC
GCCCACGTGCCGCTGACCGCCCGGCGCGTCACCGGCATCGTCTCGCGCGGCGGCTCGATCATGGCCCGCTGGTGCCTCGC
CGGGCACCGGGAATCGTTCCTCTACGAGCGGTTCGACGAGATCTGCGACATCATGCGGGCCTACGACGTCTCGTTCTCGC
TGGGCGACGGCCTGCGCCCGGGCTCGATCGCCGACGCCAACGACGCCGCCCAGTTCGGCGAGCTGGAGACGCTGGGCGAG
CTGACCAAGGTCGCCTGGGACAAGGGCTGTCAGGTGATGATCGAGGGCCCCGGCCACGTGCCGATGCACAAGATCAAGGT
CAACATGGAGAAGCAGCTGAAGGAGTGCGGCGAGGCGCCGTTCTACACCCTCGGCCCGCTGACCACCGACATCGCCCCCG
GCTACGACCACATCACCTCGGGCATCGGCGCCGCGATGATCGGCTGGTTCGGCACCGCGATGCTCTGCTACGTCACGCCG
AAGGAGCATCTCGGCCTGCCCGATCGGGACGACGTGAAGACCGGCGTGATCACCTACAAGATCGCCGCCCACGCCGCCGA
CCTCGCCAAGGGGCATCCCGCCGCGCAGCTCCGGGACGACGCGCTCAGCCGCGCCCGGTTCGACTTCCGCTGGGAGGACC
AATTTAACCTGGGCCTCGACCCGGATACGGCGCGGCGCTTCCACGACGAGACCCTGCCGAAGGATGCCCACAAGGTCGCG
CATTTCTGCTCGATGTGCGGGCCGAAATTCTGCTCGATGAAGATCACGCAGGACCTGCGCGCCGAGGTGCTGGCGATGGA
GGAGGCCGGCGAGGTCGTGGGCGCGGCGCCCGCGATGTCGAAGGCCGAGGCCGAAGCCGGCATGCGGGCGAAGTCGCAGG
AGTTCCTGGCCGAGGGCGGCAAGCTCTACGTCGACGCCGCCGAGTGA

Protein sequence :
MNAPVLPKDVKGSPETVTTGPVTGSRKAYASPAGRPDIRVPYREIVLSDPKEEPVRVYDPSGPYTETDARIDLNAGLPGV
REPWIAARGYASVAPRAVKPEDNGFAGDKLVAPCPAERTVRKAAPGQMVTQYEFARAGIITEEMIYVAHRENVCREAMLA
GAEAALADGQSFGASVPPFITPEFVRDEIARGRAIIPANINHTELEPMAIGRNFLVKINANIGNSAVTSSAADEVEKLVW
SIRWGADTVMDLSTGRNIHNIRSWIIRNSPVPIGTVPIYQALEKVGGDPLKLDWEVFKDTLIEQAEQGIDYFTIHAGVRL
AHVPLTARRVTGIVSRGGSIMARWCLAGHRESFLYERFDEICDIMRAYDVSFSLGDGLRPGSIADANDAAQFGELETLGE
LTKVAWDKGCQVMIEGPGHVPMHKIKVNMEKQLKECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTP
KEHLGLPDRDDVKTGVITYKIAAHAADLAKGHPAAQLRDDALSRARFDFRWEDQFNLGLDPDTARRFHDETLPKDAHKVA
HFCSMCGPKFCSMKITQDLRAEVLAMEEAGEVVGAAPAMSKAEAEAGMRAKSQEFLAEGGKLYVDAAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 64
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 64
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 1e-176 62