Gene Information

Name : Mrad2831_2282 (Mrad2831_2282)
Accession : YP_001754960.1
Strain : Methylobacterium radiotolerans JCM 2831
Genome accession: NC_010505
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 2412514 - 2413917 bp
Length : 1404 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCGGCAAAGCGGGGCCCGCGCGCTCGACGCCGCGCAGAAGACCCGAGCCGACTCGATGCACGACATCCGCGCCATCCG
GGAGAACCCGGACGCCTTCGACCGCGACCTCCAGCGCCGGGGCCTCGCGCCGCTCTCGGCCGAGCTGATCGCCCTCGATG
AGGCGCGGAAGTCGTCCGTCTCGGCCGCGCAGGCCAACCAGGAGCGGCGCAACGCCCTGGCCAAGGAGATCGGCGGCGCC
AAGAAGGCCAAGGACGAGGACCGCGCCGCCGCCCTGATGGCGGAGGTCGCGGCCCTGAAGGCGGCCGAGCCCGAGCTGAA
GGCCGCGCAGGACGCGGCCGACAGGACCCTGGCAGACCGCCTCGCCGCGATCCCGAACCGGCCGAAGCCCGACGTGCCGG
AGGGCGCGGACGAGCACGGCAACGTCCTCTACCGCAGCCACGCCGCGACCCGCGAGCGGCTGACCGAGGGCCGCGAGCAT
TTCGAGCTCGGCGAGGCCTCGGGCCTGATGGATTTCGAGGCGGCGGCCAAGCTGTCCGGCTCGCGCTTCGTGGTGCTCAA
AGGCCAGCTCGCCCGGCTGGAGCGGGCGCTCGGCCAGTTCATGCTCGACCTGCACACGCAGGAGCACGGCTACCTGGAGG
TGGCGCCGCCGGTGCTGGTGCGCGACGCCGCCATGTTCGGTACCGCGCAGCTGCCGAAGTTCGAGGACGACCAGTTCTCG
GTCTTCAAGGGCCTCGACTACGTCAGGTCGCTGCAGGGGCAGGCCGGCGCCGACACCGCCCCGGTCAGCGACGAGCATTT
CTGGCTCGTTCCCACAGCCGAGGTGCCGCTCACGAACCTCGTCCGCGAGGCGATCCTCCGCGAGGAGGAGCTGCCCCTGC
GGTTCACCGCGCTGACGCCCTGCTTCCGGGCCGAAGCGGGGGCGGCGGGGCGCGACACCCGCGGCATGCTGCGCCAGCAC
CAGTTCAGCAAGGTCGAGCTGGTCTCGATCACGACGCCGGAGGAATCCGCCAACGAGCACGAGCGGATGCTGACCAGCGC
CGAGGCCGTGCTGAAGAAGCTCGATCTGCCCTACCGGGTGATGACGCTCTGCACCGGCGACATGGGCTTCGCCAGCCAGA
AGACCTACGACATCGAGGTCTGGGTGCCGGGCCAGCGCACCCACCGCGAGATCTCGTCCTGCTCGGTCTGCGGCGACTTC
CAGGCGCGGCGGATGAACGCCCGCTACCGCGGCAAGGACGGCAAGCCGGCCTATGTCCACACCCTCAACGGCTCGGGCGT
GGCGGTCGGTCGCGCGCTCATCGCCGTGATGGAGAACTACCAGAACCCGGACGGGAGCATCACGGTCCCGTCGGTGCTCC
ACCCCTACATGGGCGGGCTCAACCGGATCGAAGGGGCCCGCTGA

Protein sequence :
MRQSGARALDAAQKTRADSMHDIRAIRENPDAFDRDLQRRGLAPLSAELIALDEARKSSVSAAQANQERRNALAKEIGGA
KKAKDEDRAAALMAEVAALKAAEPELKAAQDAADRTLADRLAAIPNRPKPDVPEGADEHGNVLYRSHAATRERLTEGREH
FELGEASGLMDFEAAAKLSGSRFVVLKGQLARLERALGQFMLDLHTQEHGYLEVAPPVLVRDAAMFGTAQLPKFEDDQFS
VFKGLDYVRSLQGQAGADTAPVSDEHFWLVPTAEVPLTNLVREAILREEELPLRFTALTPCFRAEAGAAGRDTRGMLRQH
QFSKVELVSITTPEESANEHERMLTSAEAVLKKLDLPYRVMTLCTGDMGFASQKTYDIEVWVPGQRTHREISSCSVCGDF
QARRMNARYRGKDGKPAYVHTLNGSGVAVGRALIAVMENYQNPDGSITVPSVLHPYMGGLNRIEGAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-80 53