Gene Information

Name : Mrad2831_1176 (Mrad2831_1176)
Accession : YP_001753866.1
Strain : Methylobacterium radiotolerans JCM 2831
Genome accession: NC_010505
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 1234518 - 1235849 bp
Length : 1332 bp
Strand : +
Note : TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: azo:azo3189 NDP sugar dehydrogenase

DNA sequence :
GTGGCTGACGGAGCGGCAGACGGCTCAGGGGAAGGCCCGGCGGACCGCTCGGCGGACAGCGTGGCGATCGTCGGCCTGGG
CTATGTCGGGCTCCCGCTCGCCCTGGCGTTCGGCCGGGGGCGGGCCACGATCGGCTACGAGCGCGCCGCCGACAAGGTGG
CGGCCTACCGGGCCGGGCACGACCCGGCCGGGGAGATCGACGCGGAGGCGTTCCGGGCCGCCGCGCACCTCGCGATCACC
GACGACCCGACCGCGCTGGGCGCGGCGGACGTGATCGTCGTCACGGTCCCGACCCCGGTGGACGCGGCCCAGTGCCCCGA
TTTCGATCTGCTGATCCGGGCCTCGGACCTCGTCGGCCGGCACATGCGGCCGGGCGCGACCGTGGTGTTCGAATCCACGG
TCTATCCCGGGGCCACCGAGGAGGTCTGCATCCCGGTCCTGGAGCGCGCCTCGGGCCTGCGCTGGAAGACGGATTTCTTC
GTCGGCTACTCGCCCGAGCGGATCAACCCGGGCGACCGGGAGCACAGCCTCGCCCGGGTGGTGAAGATCGTCGCCGGCGA
CACCCCCGAGACCCTGGAGCGGCTCAAGGCCCTCTACGGGTCGATCATCGAGGCGGGGCTCCACGCCGCCTCGTCCATCC
GGGTCGCCGAGGCCGCCAAGGTCATCGAGAACACCCAGCGCGACCTGAACATCGCGCTCATGAACGAGCTGTCGCTGATC
TTCGACAAGCTCGACCTCGACACCCAGGAGGTCCTCGCGGCGGCGGGGACCAAGTGGAACTTCCTGCCGTTCCGCCCCGG
GCTGGTCGGCGGCCACTGCATCGGCGTCGACCCGTACTACCTGACCCACAAGGCCGCGATGATCGGCTACCACCCGCAGG
TGATCCTGGCCGGGCGGCGGATCAACGACAGCATGGCGGCCCACGTCGCCCGCAGCACGGTGAAGCGGATCGTCCGGCGC
GGCGGGACCGGGCGGGCGCGGGTCATCGTCCTGGGCCTGACCTTCAAGGAGAACTGCGCCGACCTGCGCAACTCGAAGGT
CGCCGACCTCGTGCGGGAGCTGGAGGAATTCGGCTGCGCCGTGTCGGTCCACGATCCCCGCGCCGGCGCGGCGGAGGCCC
GGGCCGAGTACGGCATCGCCCTCGTCGACTGGGCCGACTTGCCCACCGAGGCCGACGCGGCCGTGATCGCGGTCCCGCAC
CGCGACTACGCCCGACTCGGCCCGGAGGCGATCGCCGCCCGGGTGAAGCCCGGCGGCCTGATCGTGGACGTGAAGGCACT
CTTCGAGAAGGCGCCGTTCGCGCGGCTGGGCTACGAGGTCTGGCGGCTGTGA

Protein sequence :
MADGAADGSGEGPADRSADSVAIVGLGYVGLPLALAFGRGRATIGYERAADKVAAYRAGHDPAGEIDAEAFRAAAHLAIT
DDPTALGAADVIVVTVPTPVDAAQCPDFDLLIRASDLVGRHMRPGATVVFESTVYPGATEEVCIPVLERASGLRWKTDFF
VGYSPERINPGDREHSLARVVKIVAGDTPETLERLKALYGSIIEAGLHAASSIRVAEAAKVIENTQRDLNIALMNELSLI
FDKLDLDTQEVLAAAGTKWNFLPFRPGLVGGHCIGVDPYYLTHKAAMIGYHPQVILAGRRINDSMAAHVARSTVKRIVRR
GGTGRARVIVLGLTFKENCADLRNSKVADLVRELEEFGCAVSVHDPRAGAAEARAEYGIALVDWADLPTEADAAVIAVPH
RDYARLGPEAIAARVKPGGLIVDVKALFEKAPFARLGYEVWRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 4e-93 51
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 9e-87 49
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 9e-87 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mrad2831_1176 YP_001753866.1 nucleotide sugar dehydrogenase VFG0431 Protein 4e-87 49