Gene Information

Name : lysS (UPA3_0061)
Accession : YP_001752141.1
Strain : Ureaplasma parvum ATCC 27815
Genome accession: NC_010503
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 77555 - 79036 bp
Length : 1482 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGGAAAGAAAATTTAGTGATCAAGAATTAATCCGTCGTACACACTTACAAGAATTAAAAAACCAAAATAAAAATCCTTT
TTTAATAACAAAAGTTGATAGAAGTATGTTTTTAAAAGACTTTGCTGAAAAATATAAAAATTTTAGCAAAGAAGAATTAC
ATAATATGGATTTAGAGAAATTGACACTTGCTGGTCGTTTAATCGGAATACGTCAAACCTTTGGGATTATTCAAGATTTT
TCAGCAAAGTTACAAATTTATATTAATAAAAAAAATGTTGCTCCAGAGGTTTTTTCAACTTTTAAATCATTAGATATTGG
TGATATTATTGAATTAGAAGGTGTAGCAATGAAAACTAATAGTGATGAAATTACTTTAAATGTTACAAACATTCGATTAG
TTGCTAAAAGTCTAAAAGTTCTCCCTGAAAAGTATCATGGATTGGTTGATGAAGAAATTAAAGCACGTCAACGTTATTTA
GATTTAATTGTTAACGATGAGACAAAAAATACTTTTATAAAACGATCTTTAATTATACGTGAAATGCGTAATTGGTTAGA
TAATAAAGGTTTTTTTGAAGTTGAAACGCCTGTTTTGCAAGATATTTTAAGTGGTGCTGCTGCTCGTCCTTTTATTACAC
ATCATAACACTTTAAATAAAGAATATTATTTAAGAATTGCTACTGAAATTGCTTTAAAAAAGTGTATTATTGGGGGTTTT
GAAAAAGTATATGAAATAGGTAGAATTTTTCGAAATGAGGGAATGGATAGTACTCATAATCCTGAATTTACTTCAGTTGA
ATTATATATTGCATATGTTGATTTATGATATATTATGCAACTAACTGAAGATTTAATTCGTCATATTGCTACTAAATTAA
ACTTATTAAATCCTACATTTAGAGGTTTTAGTATTGATTTAAATAAACCTTTTAAAAAAGCTCATATGGTTGATTTAATT
AATGAATATGTTGGTGTTAATTTTTTTGAAGTTAAAAGCGATGAACAAGCAATTGAATTAGCAAAAAAACACCATGTTAA
ATTATTAGATCATCAAAAAAACTTTGGTCATATCGTTAATGCTTTTTTTGAAACTTTTGTTGAAGAAAAATTAGTTGAAC
CAACATTTGTATATGGTCATCCGTTACAAGTTTCTCCACTTACTAAAAAGAATCAGAGTGATCCTCGTTTTGTAGATCGT
TTTGAATTATTTATTTGTCAAAAAGAATTTGCTAATGCTTATAGTGAAATTAATGATCCAATTGATCAATATGAACGTTT
TATCGCACAGTTAGAAGAAGCTAAATTAGGAAATGACGAAGCAAGTGAATTAGATATGGAATTTATTGAGGCCTTAGAAT
ATGGTATGCCTCCAACAGGTGGTTTGGGAATCGGTGTTGATCGTTTAGTAATGCTGTTAACAAGTAATGATAGTATTCGT
AATGTTTTATTATTTCCTCACATGAAAGATAAAACAAAATAA

Protein sequence :
MERKFSDQELIRRTHLQELKNQNKNPFLITKVDRSMFLKDFAEKYKNFSKEELHNMDLEKLTLAGRLIGIRQTFGIIQDF
SAKLQIYINKKNVAPEVFSTFKSLDIGDIIELEGVAMKTNSDEITLNVTNIRLVAKSLKVLPEKYHGLVDEEIKARQRYL
DLIVNDETKNTFIKRSLIIREMRNWLDNKGFFEVETPVLQDILSGAAARPFITHHNTLNKEYYLRIATEIALKKCIIGGF
EKVYEIGRIFRNEGMDSTHNPEFTSVELYIAYVDLWYIMQLTEDLIRHIATKLNLLNPTFRGFSIDLNKPFKKAHMVDLI
NEYVGVNFFEVKSDEQAIELAKKHHVKLLDHQKNFGHIVNAFFETFVEEKLVEPTFVYGHPLQVSPLTKKNQSDPRFVDR
FELFICQKEFANAYSEINDPIDQYERFIAQLEEAKLGNDEASELDMEFIEALEYGMPPTGGLGIGVDRLVMLLTSNDSIR
NVLLFPHMKDKTK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 1e-89 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001752141.1 lysyl-tRNA synthetase VFG1668 Protein 8e-90 41