Gene Information

Name : guaA (PputW619_4193)
Accession : YP_001751042.1
Strain : Pseudomonas putida W619
Genome accession: NC_010501
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 4623066 - 4624643 bp
Length : 1578 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGCCCTCGACATTCACGCTCACCGCATCCTGATCCTCGATTTCGGTTCCCAGTACACCCAACTGATCGCCCGCCGCGT
GCGTGAGATCGGTGTCTACTGCGAACTGCACCCGTTCGACATGGACGATGAAGCGATCCGCGAATTCAACCCGCGCGGCA
TCATCCTCGCCGGCGGCCCCGAGTCGGTCCACGAAGCCAACAGCCCGCGTGCACCGCAGGCCGTGTTCGACCTGAATGTA
CCTTTGCTGGGCATCTGCTACGGCATGCAGACCATGGCCGAGCAGTTGGGTGGCAAGGTCGAAGGTTCGGACCTGCGCGA
GTTCGGTTATGCCCGCGTTGACGTGGTCGGCAAGAGCCGCCTGCTCGACGGCATCGAAGACCACGTTGATGGCGACGGCG
TACTGGGCCTGGACGTGTGGATGAGCCACGGCGACAAGGTCACCCAGATGCCGGGCAACTTCAACATCCTGGCCAGCACC
CCGAGCTGCCCGATCGCCGGCATGTTCGACGACGCGCGCGGCTACTACGGCGTGCAGTTCCACCCGGAAGTGACCCACAC
CAAGCAAGGCGGTCGCATCCTGTCCCGCTTCGTGCAGGATATCTGTGGCTGTGAAGCCCTGTGGACGCCTTCGAACATCG
TCGAAGACGCCATCGCCCAGGTGCGTCAGCAAGTCGGCTCGGCCAACGTCCTGCTGGGCCTGTCTGGCGGTGTCGACTCC
TCCGTGGTAGCCGCGCTGCTGCACCGCGCCATCGGCGACCAGCTGACTTGCGTCTTTGTCGACAACGGCCTGCTGCGCCT
GCACGAAGGCGACCAGGTGATGGCCATGTTCAAGGAGAACATGGGCGTCAAAGTGATCCGCGCCGATGCCGAGAAGCAGT
TCCTCGACAACCTGGAAGGCGAAGCCGACCCGGAGAAGAAGCGCAAGATCATCGGCCGTACCTTCATCGACGTGTTCGAT
GCCGAAGCCAGCAAACTGGACAACATCCAGTTCCTCGCCCAGGGCACCATCTACCCGGACGTGATCGAGTCGGCCGGCGC
CAAGAGCGGCAAGGCCCACGTGATCAAGTCGCACCACAACGTGGGTGGTCTGCCGGAGGAAATGAACCTCAAGCTGGTCG
AACCGCTGCGTGAGCTGTTCAAGGACGAAGTGCGCAAGATCGGCCTGGAACTCGGCCTGCCGTACGACATGGTCTACCGC
CACCCGTTCCCGGGCCCGGGCCTGGGTGTGCGTATCCTCGGTGAAGTGAAGAAGGAGTACGCCGACATCCTGCGTCGCGC
CGACCACATCTTCATCGAAGAGCTGCGCAAGGCCGACTGGTACCACAAGACCAGCCAGGCGTTCGTGGTGTTCCAGCCGG
TGAAATCGGTTGGCGTCGTGGGCGACGGCCGTCGCTACGCCTGGGTCGTGGCCCTGCGTGCTGTCGAGACCGTGGACTTC
ATGACCGCGCGCTGGGCGCACCTGCCTTACGACCTGCTGGAAACCGTCAGCGGCCGTATCATCAACGAAATCGACGGTAT
CTCGCGCGTGACTTACGACGTGTCGAGCAAGCCGCCGGCCACTATCGAGTGGGAGTGA

Protein sequence :
MALDIHAHRILILDFGSQYTQLIARRVREIGVYCELHPFDMDDEAIREFNPRGIILAGGPESVHEANSPRAPQAVFDLNV
PLLGICYGMQTMAEQLGGKVEGSDLREFGYARVDVVGKSRLLDGIEDHVDGDGVLGLDVWMSHGDKVTQMPGNFNILAST
PSCPIAGMFDDARGYYGVQFHPEVTHTKQGGRILSRFVQDICGCEALWTPSNIVEDAIAQVRQQVGSANVLLGLSGGVDS
SVVAALLHRAIGDQLTCVFVDNGLLRLHEGDQVMAMFKENMGVKVIRADAEKQFLDNLEGEADPEKKRKIIGRTFIDVFD
AEASKLDNIQFLAQGTIYPDVIESAGAKSGKAHVIKSHHNVGGLPEEMNLKLVEPLRELFKDEVRKIGLELGLPYDMVYR
HPFPGPGLGVRILGEVKKEYADILRRADHIFIEELRKADWYHKTSQAFVVFQPVKSVGVVGDGRRYAWVVALRAVETVDF
MTARWAHLPYDLLETVSGRIINEIDGISRVTYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 7e-128 51
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-127 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 9e-128 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-110 47