Gene Information

Name : PputW619_3295 (PputW619_3295)
Accession : YP_001750149.1
Strain : Pseudomonas putida W619
Genome accession: NC_010501
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 3635452 - 3637419 bp
Length : 1968 bp
Strand : +
Note : KEGG: pfo:Pfl_3001 DNA topoisomerase III; TIGRFAM: DNA topoisomerase III; PFAM: TOPRIM domain protein; DNA topoisomerase type IA central domain protein; DNA topoisomerase type IA zn finger domain protein; SMART: DNA topoisomerase I ATP-binding; DNA topois

DNA sequence :
ATGCGCCTGTTCATCTGCGAGAAACCTTCCCAAGCCCGCGACATCGCCCGGGTGCTGCAGGCCAGCCGCCGCGGTGATGG
TTGCCTGACGGGTCAGAACCTCACCGTCACCTGGTGCGTCGGTCATCTGCTGGAGACCGCGCCTCCTGAAACCTATGGCG
ATTACAAACGCTGGTCGCTGGACGACCTGCCGATCATTCCCAGCCGCTGGCAACTGGTGGCCAAACCCAAGGTCGCTGGC
CAGCTGAAGGTGATCAGCCAGCTGCTGCGCACTTGCAGCGAAGTGGTGATCGCCACCGACGCCGACCGCGAAGGCGAGAT
GATCGCCCGGGAGATTCTCGAACGATGCCAGTATCAGGGGCCGATTCTGCGCCTGTGGCTGTCCGCGTTGGATGAAACAT
CGATCCGTCGAGCCTTGAGCGCATTGCGCCCGGGGGAGCAGACCTTGCCGCTGTACCACTGTGCACTCGCCCGCTCCCGT
GCCGATTGGCTGGTCGGCATCAACTTGAGCCGGCTGTTCACGCTGCTCGGCCGCCGCGCTGGCTTCGATGGCCTGCTGCC
GGTGGGACGTGTGCAAACCCCCACCTTGCGCCTGGTGGTCGAGCGCGACCGGGCGATCGCCAGCTTTGTGCCGCTACCAT
TCTGGACCGTCGATGCGCACCTGGAACAGGACGGGATCCGTTTTCACGCGCGCTGGCAGGCCCCGAACGCGGTCAGCGAT
GCGGTTGGACGCTGTATCGACGAAACCGCCGCGCAGCAGGCGCTCAGGCGCCTCACTCAAGCTGGCAGCGCACAGATCGA
CAGCGTCGAGGTCGAGCGGGTGCGGGAAGGTCCGCCACTGCCGTTCGACCTGGGCACGCTGCAGGAGATCTGCTCGGCCA
AGCTCGGACTCGGAGCACAGGAGACCCTGGCCACTGCCCAGGCCCTGTACGAGACCCACAAGGTGACGACCTACCCGAGA
AGCGACTGCGGCTACTTGCCGGAGAGCATGCTCGATGAGGTGCCGCGCGTCCTTCACGCCTTGGCCGCCGCCGCACCATC
GCTGGGGGAAATCCTCAAGGAGGTCGACCCCAGCCGCCGCTCCCGTGCCTGGAACAGCAGCAAGATCACCGCGCACCACG
GCATCATTCCCACCGCCGTCACGCTGGATTTGGCGCAGCTCTCCGAGCGCGAGCGTGCGGTTTACACGCTGATTCGCGCA
CGCTACCTCGCGCAGTTCATGCCCGAGCACGAGTACCTGAAAACCCAGGCGCAGTTGCACAGCCAGGCAGATCACCTGGT
GGCGCGCGGCAAACAGATCCTGGCCCGCGGCTGGAAGGCAGTGATCAACGAGGCCGACGGTAACGAGCCGGCCGAACAGG
CGCAGCGATTACCCACGTTGCGTGAATCCGCGACGGTGGCGCTGATCGACGCCACCCTCAACGCACAGCGCACACAACCG
CCCAAGGCCTACACCGAAGGCACCCTGGTCAGAGCGATGAAAACCATCGCCAACCAGGTGGCTGATTCGCGGCTCAAGCA
GAAGCTCAAGGACAGCTGCGGGCTCGGTACCGAGGCCACCCGCGCGGCCATCATCCAGGGCCTGATCGATCACGGTTACC
TGACCAAGAAGAAACGCAGCCTGGCTGCCTCCGCGGCGGCGCATACCTTGATCGAAGCGGTGCCACCAGAGGTGGCCGAC
CCGGTCATGACCGCACTGTGGGAGCAGGCGCTGGACCGTATCGAGTCGGGCCAACTGAGCGTCGAGACCTTTCTCGCCAA
GCAGACAGAATGGCTGACTCGACTGGTGCGCAGTAACGCGACGCTCACCCTGCGCCCGCCCCCCAGCAAGGGGCCCTTCT
GCCCGGTCTGCCGCAGCGCCATGCGCCAACGCAAAGGTCGCACCGGCAGCTTCTGGTCGTGTATCCGCTACCCCGAATGC
AAGGGCACCAAACCGGTGGCAAAAACCAAGCGGGCGAAAAACACATGA

Protein sequence :
MRLFICEKPSQARDIARVLQASRRGDGCLTGQNLTVTWCVGHLLETAPPETYGDYKRWSLDDLPIIPSRWQLVAKPKVAG
QLKVISQLLRTCSEVVIATDADREGEMIAREILERCQYQGPILRLWLSALDETSIRRALSALRPGEQTLPLYHCALARSR
ADWLVGINLSRLFTLLGRRAGFDGLLPVGRVQTPTLRLVVERDRAIASFVPLPFWTVDAHLEQDGIRFHARWQAPNAVSD
AVGRCIDETAAQQALRRLTQAGSAQIDSVEVERVREGPPLPFDLGTLQEICSAKLGLGAQETLATAQALYETHKVTTYPR
SDCGYLPESMLDEVPRVLHALAAAAPSLGEILKEVDPSRRSRAWNSSKITAHHGIIPTAVTLDLAQLSERERAVYTLIRA
RYLAQFMPEHEYLKTQAQLHSQADHLVARGKQILARGWKAVINEADGNEPAEQAQRLPTLRESATVALIDATLNAQRTQP
PKAYTEGTLVRAMKTIANQVADSRLKQKLKDSCGLGTEATRAAIIQGLIDHGYLTKKKRSLAASAAAHTLIEAVPPEVAD
PVMTALWEQALDRIESGQLSVETFLAKQTEWLTRLVRSNATLTLRPPPSKGPFCPVCRSAMRQRKGRTGSFWSCIRYPEC
KGTKPVAKTKRAKNT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 0.0 59
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 0.0 57
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 0.0 57
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 8e-146 47
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 9e-155 47
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 2e-154 46
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 2e-154 46
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 2e-154 46