Gene Information

Name : PputW619_1513 (PputW619_1513)
Accession : YP_001748387.1
Strain : Pseudomonas putida W619
Genome accession: NC_010501
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 1669518 - 1670282 bp
Length : 765 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAGCCTTGACTTCACCGTGGTCATTCCCGCCCGTCTGCGCTCGACGCGTCTGCCGGGTAAGCCGTTGCTGCTGATCGC
CGGCAAACCGATGGTTCAGCATGTGTGGGAGCAGGCGCGCAAGAGCGGTGCCGGCCGTGTGGTCATCGCCACCGATGACG
CCAGTATCGTCGAGGCCTGTCAGGCCTTTGGTGCTGAAGTACTGATGACCCGCGCCGACCATGAGTCGGGTACCGACCGC
CTGGCTGAAGTGGCCGCGCAGCTTGGCCTGCCTGCCGACGCCATCGTGGTCAACGTCCAGGGTGATGAGCCGCTTATTCC
GCCGGTGATCATCGATCAGGTCGCAGCCAACCTGGCGGCGCATCCGGAGGCAGGTATTGCGACCCTGGCCGAGCCGATCC
ATGACCCCGAAACCGTGTTCAACCCCAATGCGGTCAAGGTGGTCAGCGACAAGAACGGGCTGGCCTTGAGCTTCAGCCGT
GCGCCGCTGCCGTGGGCGCGTGATGCCTTCGCCAAGGACCGCAATCAACTACCGCAGGGCGTGCCCTACCGCCGCCATAT
CGGCATGTACGCCTACCGCGTTGGTTTCCTTCAGGATTTCGTCAGCTGGGGCCCGTGCTGGCTCGAGCAGACCGAGGCGC
TTGAACAGCTGCGTGCGCTGTGGCATGGCGTGCGTATCCACGTGGCGGATGCCATCGAGGCGCCAGCAGTGGGTGTCGAT
ACTGCACAAGACCTCGAGCGCGTTCGGCGCTTGCTGGAGGCCTGA

Protein sequence :
MSLDFTVVIPARLRSTRLPGKPLLLIAGKPMVQHVWEQARKSGAGRVVIATDDASIVEACQAFGAEVLMTRADHESGTDR
LAEVAAQLGLPADAIVVNVQGDEPLIPPVIIDQVAANLAAHPEAGIATLAEPIHDPETVFNPNAVKVVSDKNGLALSFSR
APLPWARDAFAKDRNQLPQGVPYRRHIGMYAYRVGFLQDFVSWGPCWLEQTEALEQLRALWHGVRIHVADAIEAPAVGVD
TAQDLERVRRLLEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 8e-39 45
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 6e-39 45
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 4e-39 44