Gene Information

Name : deoA (EcSMS35_4931)
Accession : YP_001746838.1
Strain : Escherichia coli SMS-3-5
Genome accession: NC_010498
Putative virulence/resistance : Unknown
Product : thymidine phosphorylase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0213
EC number : 2.4.2.4
Position : 5046159 - 5047481 bp
Length : 1323 bp
Strand : +
Note : Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate

DNA sequence :
TTGTTTCTCGCACAAGAAATTATTCGTAAAAAACGTGATGGTCATGCGCTGAGTGATGAAGAAATTCGTTTCTTTATCAA
CGGCATTCGCGACAACACTATCTCCGAAGGGCAGATTGCCGCCCTCGCGATGACCATTTTCTTCCACGATATGACAATGC
CTGAGCGTGTCTCGCTGACCATGGCGATGCGAGATTCAGGAACCGTTCTCGACTGGAAAAGCCTGCATCTGAATGGCCCG
ATTGTTGATAAACACTCGACCGGCGGTGTCGGCGATGTGACTTCGCTGATGTTGGGGCCGATGGTCGCTGCCTGTGGCGG
CTATATTCCGATGATCTCCGGTCGCGGCCTCGGTCATACTGGCGGTACGCTCGACAAACTGGAATCCATCCCTGGCTTCG
ACATTTTCCCGGATGACAACCGTTTCCGCGAAATTATTAAAGACGTCGGCGTGGCGATTATCGGTCAGACCAGCTCACTG
GCTCCGGCGGATAAACGTTTCTACGCGACCCGTGATATTACCGCAACCGTGGACTCCATCCCGCTGATCACTGCCTCGAT
CCTGGCGAAGAAACTGGCGGAAGGTCTGGATGCGCTGGTGATGGACGTGAAAGTGGGTAGCGGCGCGTTTATGCCGACCT
ACGAACTTTCTGAAGCCCTTGCCGAAGCGATTGTTGGCGTAGCTAACGGCGCTGGCGTGCGTACCACCGCGCTGCTCACC
GATATGAATCAGGTACTGGCCTCCAGTGCAGGTAACGCGGTTGAAGTTCGTGAAGCGGTGCAGTTCCTGACGGGTGAGTA
TCGTAACCCGCGTCTGTTTGATGTCACAATGGCGCTGTGCGTAGAGATGCTTATCTCCGGCAAACTGGCGAAAGATGACG
CCGAAGCGCGCGCGAAATTGCAGGCGGTGCTGGACAACGGTAAAGCGGCAGAAGTCTTTGGTCGTATGGTAGCGGCACAA
AAAGGCCCGACTGACTTCGTTGAGAACTACGCGAAGTATCTGCCGACAGCGATGCTGACGAAAGCAGTCTATGCTGATAC
CGAAGGGTTTGTCAGTGAAATGGATACCCGCGCGCTGGGGATGGCAGTGGTTGCAATGGGCGGCGGACGCCGTCAGGCAT
CTGACACCATCGATTACAGCGTCGGCTTTACTGATATGGCGCGTCTGGGCGACCAGGTAGACGGTCAGCGTCCGCTGGCA
GTTATCCACGCGAAAGACGAAAACAGCTGGCAGGAAGCGGCGAAAGCGGTGAAAGCGGCAATTAAACTTGCCGATAAAGC
ACCGGAAAGCACACCAACTGTCTATCGTCGTATCAGTGAATAA

Protein sequence :
MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGP
IVDKHSTGGVGDVTSLMLGPMVAACGGYIPMISGRGLGHTGGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSL
APADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLT
DMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQ
KGPTDFVENYAKYLPTAMLTKAVYADTEGFVSEMDTRALGMAVVAMGGGRRQASDTIDYSVGFTDMARLGDQVDGQRPLA
VIHAKDENSWQEAAKAVKAAIKLADKAPESTPTVYRRISE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
deoA YP_005163381.1 Thymidine phosphorylase Not tested Not named Protein 3e-64 45