Gene Information

Name : EcSMS35_4753 (EcSMS35_4753)
Accession : YP_001746674.1
Strain : Escherichia coli SMS-3-5
Genome accession: NC_010498
Putative virulence/resistance : Unknown
Product : phage integrase family site specific recombinase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 4851586 - 4852851 bp
Length : 1266 bp
Strand : +
Note : identified by match to protein family HMM PF00589

DNA sequence :
ATGGCATTAACAGATATCAAAGTCAGAGCAGCCAAGCCAACGGATAAGCAATATAAGCTGACTGATGGTGGCGGTATGCA
TCTGCTTGTCCATCCAAATGGTTCTAAGTACTGGCGTTTGCAGTACCGTTATGAGGGAAAGCAAAAAATGCTGGCACTTG
GGGTTTATCCTGAAATCACACTAGCGGATGCCAGAGTACGTCGTGACGAGGCGCGTAAGCTGCTTGCGAATGGCGTCGAT
CCGGGAGACAAAAAGAAAAATGATAAGGTTGAACAGAGTAAAGCACGAACCTTTAAAGAAGTCGCGATTGAGTGGCATGG
CACCAATAAAAAGTGGTCTGAAGATCACGCCCATCGTGTGCTAAAAAGTCTGGAAGATAATCTTTTTGCAGCGCTTGGTG
AACGTAATATCGCTGAGTTAAAAACTCGAGATTTATTAGCACCCATTAAGGCCGTAGAAATGTCTGGACGTCTTGAAGTG
GCCGCTCGTCTTCAGCAGCGCACTACAGCCATCATGCGCTATGCAGTGCAAAGTGGGTTAATTGATTATAACCCGGCACA
AGAGATGGCTGGGGCGGTTGCTTCCTGTAATCGACAACATCGTCCCGCGCTTGAATTAAAGCGCATCCCTGAGTTGCTTA
CAAAAATAGATAGCTATACTGGTAGGCCGCTAACCCGATGGGCGACAGAACTCTCTTTGCTGATCTTTATTCGGTCCAGT
GAGCTGCGTTTTGCTCGTTGGTCAGAGATCGATTTCGAAGCGTCTATATGGACTATCCCACCGGAGCGGGAGCCTATTCC
TGGAGTGAAACATTCCCATAGAGGCTCAAAAATGCGTACAACGCATCTAGTGCCTCTTTCAACGCAAGCTCTTGCAATTT
TAAAGCAGATAAAACAGTTTTGTGGGGCCCATGACTTGATATTTATTGGTGATCACGATTCGCACAAACCCATGAGTGAG
AATACGGTAAATAGTGCGTTACGGGTCATGGGGTATGATACAAAAGTAGAGGTTTGTGGTCATGGCTTTCGAACAATGGC
CTGTAGTTCATTGGTCGAATCAGGTTTGTGGTCTCGTGATGCTGTTGAACGTCAGATGAGCCACATGGAGCGAAATTCAG
TGAGGGCCGCGTATATCCATAAAGCAGAGCATCTGGAAGAACGCCGCTTGATGCTACAATGGTGGGCCGATTTTCTGGAT
GCAAACAGAGAAAAATTTATCAGTCCATTTGAATATGCAAAGATTAATAATCCATTAAAACAGTAA

Protein sequence :
MALTDIKVRAAKPTDKQYKLTDGGGMHLLVHPNGSKYWRLQYRYEGKQKMLALGVYPEITLADARVRRDEARKLLANGVD
PGDKKKNDKVEQSKARTFKEVAIEWHGTNKKWSEDHAHRVLKSLEDNLFAALGERNIAELKTRDLLAPIKAVEMSGRLEV
AARLQQRTTAIMRYAVQSGLIDYNPAQEMAGAVASCNRQHRPALELKRIPELLTKIDSYTGRPLTRWATELSLLIFIRSS
ELRFARWSEIDFEASIWTIPPEREPIPGVKHSHRGSKMRTTHLVPLSTQALAILKQIKQFCGAHDLIFIGDHDSHKPMSE
NTVNSALRVMGYDTKVEVCGHGFRTMACSSLVESGLWSRDAVERQMSHMERNSVRAAYIHKAEHLEERRLMLQWWADFLD
ANREKFISPFEYAKINNPLKQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 0.0 99
int AAK16198.1 Int Not tested PAI-I AL862 Protein 2e-149 69
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 2e-149 69
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 3e-147 69
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 4e-147 69
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 1e-147 69
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 1e-147 69
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 1e-147 69
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 8e-149 69
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 1e-147 68
int-phe AAL60261.1 Int-phe Not tested LEE Protein 5e-149 68
int AAK00456.1 Int Not tested SHI-1 Protein 3e-137 68
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 7e-149 68
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 2e-145 68
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 7e-149 68
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 8e-147 68
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 2e-148 68
int AAL51003.1 CP4-like integrase Not tested LEE Protein 9e-149 68
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 5e-149 68
int AAL51028.1 CP4-like integrase Not tested LEE Protein 5e-149 68
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 3e-148 68
int CAC81896.1 integrase Not tested LEE II Protein 2e-138 67
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 5e-130 60
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 5e-130 60
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 4e-120 59
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 5e-84 56
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 3e-117 56
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 3e-117 56
int YP_002346908.1 integrase Not tested HPI Protein 5e-115 55
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 5e-115 55
int2 NP_993013.1 integrase Not tested HPI Protein 5e-115 55
int CAA08754.1 integrase Not tested HPI Protein 1e-115 55
int CAA21384.1 - Not tested HPI Protein 5e-115 55
int CAB59974.1 integrase Not tested HPI Protein 2e-116 55
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 4e-97 55
unnamed AAD17660.1 unknown Not tested HPI Protein 1e-111 53
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 6e-105 53
aec33 AAW51716.1 Int Not tested AGI-3 Protein 4e-87 44
int AAD44730.1 Int Not tested SHI-2 Protein 2e-86 44
int CAC39282.1 integrase Not tested LPA Protein 4e-87 44
ECs4534 NP_312561.1 integrase Not tested LEE Protein 6e-86 43
int AAC31482.1 CP4-like integrase Not tested LEE Protein 5e-86 43
int ACU09430.1 integrase Not tested LEE Protein 5e-86 43
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 6e-86 43
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 9e-79 43
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 6e-85 43
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 8e-85 43
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 8e-85 43
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 5e-79 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EcSMS35_4753 YP_001746674.1 phage integrase family site specific recombinase VFG1536 Protein 0.0 99
EcSMS35_4753 YP_001746674.1 phage integrase family site specific recombinase VFG0626 Protein 4e-148 69
EcSMS35_4753 YP_001746674.1 phage integrase family site specific recombinase VFG1693 Protein 3e-147 68
EcSMS35_4753 YP_001746674.1 phage integrase family site specific recombinase VFG0783 Protein 3e-86 43
EcSMS35_4753 YP_001746674.1 phage integrase family site specific recombinase VFG0598 Protein 4e-85 43